A5051400540- Skin and Cellular Biology Research
- Ocular Surface and Contact Lens
- Bone health and osteoporosis research
- Dermatological and Skeletal Disorders
- Retinal and Macular Surgery
- Glaucoma and retinal disorders
- Soft tissue tumor case studies
- Ocular Infections and Treatments
- Retinal Diseases and Treatments
- Hair Growth and Disorders
- Nail Diseases and Treatments
- Visual perception and processing mechanisms
- Infectious Diseases and Tuberculosis
- Metabolism, Diabetes, and Cancer
- Ocular Oncology and Treatments
- Vestibular and auditory disorders
- melanin and skin pigmentation
- Intraocular Surgery and Lenses
- Streptococcal Infections and Treatments
- Child Abuse and Related Trauma
- Retinal Development and Disorders
- Autoimmune and Inflammatory Disorders
- Autoimmune Bullous Skin Diseases
- Otolaryngology and Infectious Diseases
- Oral Health Pathology and Treatment
Tufts Medical Center
2014-2022
Tufts Children's Hospital
2020
Tufts University
2020
Hispanics in Philanthropy
2016
Boston Children's Hospital
2008
Beth Israel Deaconess Medical Center
1998
Abstract Human growth hormone (hGH) and insulin-like factor I (IGF-I) both stimulate bone formation have been proposed as therapeutic agents for osteoporosis. We examined the effect of hGH IGF-I alone in combination on size, mineral content (BMC), density (BMD) 10- to 12-week-old growing female Sprague-Dawley rats. Sixty rats were assigned treatment with either placebo, hGH, IGF-I, or 4 weeks. After weeks, right femurs tibias excised, ex vivo BMC area tibia femur measured by dual-energy...
Patients taking suppressive doses of T4 are thought to have accelerated bone loss and increased risk osteoporosis. We therefore randomize 55 patients treatment with pamidronate (APD) 30 mg i.v. every 3 months for 2 yr (APD/T4), or placebo (placebo/T4). had measurements mineral density (BMD) the spine, hip, radius, total body 6 yr. There was no significant at any site in placebo/T4 group. Ninety five percent confidence intervals excluded a rate > 0.89%/yr spine 0.31%/yr hip. When men were...
The purpose of this article is to report a case Lemierre syndrome associated mycotic aneurysm the intracavernous carotid artery leading cavernous sinus in an otherwise healthy, young man setting COVID-19 infection.An 18-year-old, healthy male athlete developed fever, chills, and headache was found be positive for with gram negative bacteremia. While on systemic antibiotic treatment, he acute, left-sided, 6th nerve palsy have bacterial sinusitis, left-sided aneurysm, thrombosis imaging...
The Parks-Bielschowsky three-step test (TST) can incorrectly indicate that a superior oblique muscle is paretic in patients with restrictive strabismus. Although this pitfall diagnosis has been widely reported, no large studies have examined the incidence of positive TST Graves disease.We performed retrospective chart review 31 consecutive orbitopathy at Children's Hospital Boston from 2003 to 2007. We analyzed ocular ductions, misalignment, and torsion, thyroid function studies.Six (20%)...
Lichen nitidus is a rare, idiopathic inflammatory condition that typically presents as small, flat-topped papules on the chest, abdomen, and upper extremities. The lesions are benign often asymptomatic self-resolve. pediatric population most affected. authors report case of lichen presenting isolated bilateral eyelid increasing in number for several years. Eventual excision antibiotic/steroid ointment prompted regression.
Ophthalmic study of collagen CVII hypomorphic mice is uniquely challenging due to the strain's published survival rate weaning 24%. Because chronic ocular fibrosis requires time develop, optimizing critical importance. In this study, standard husbandry practices were enhanced by addition sterilized diet and drug delivery gels, acidified water, irradiated food pellets, cellulose fiber bedding, minimal handling, removal siblings within 2-3 wk from birth, a preferred housing location. Survival...
Purpose: Dystrophic epidermolysis bullosa (DEB) is a devastating condition that causes painful corneal abrasions and vision loss. Epidermolysis Bullosa Eye Disease Index (EB-EDI) for the first time captures quantifies EB-specific assessment of ocular symptoms activities daily living scales. This survey will become critical in developing new interventions on patients' quality life. Methods: Three-part set EB-EDI baseline, interval, Ocular Surface (OSDI) was distributed to 92 patients with DEB...