- Immunodeficiency and Autoimmune Disorders
- Sinusitis and nasal conditions
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Genomic variations and chromosomal abnormalities
- Cytomegalovirus and herpesvirus research
- Pediatric health and respiratory diseases
- Myasthenia Gravis and Thymoma
- Pneumocystis jirovecii pneumonia detection and treatment
- Viral gastroenteritis research and epidemiology
- COVID-19 Clinical Research Studies
- Salivary Gland Tumors Diagnosis and Treatment
Rasool Akram Hospital
2022-2024
Iran University of Medical Sciences
2021-2024
Abstract Background Chronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and divided into two subgroups defined as CRS with nasal polyps (CRSwNP) without (CRSsNP). CRSwNP displays T helper (Th)2 biased phenotype, based on sensitivity or tolerance to aspirin non-steroidal anti-inflammatory drugs (NSAID), further subdivided Aspirin-exacerbated respiratory (AERD) non-AERD groups. Considering the challenge of diagnosis treatment in patients CRSwNP, particularly AERD subtype,...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex disorder and effective treatment remains major challenge. Some antibiotics anti-inflammatory properties are reported to have potential be used as an adjunct therapy in the management of chronic airway inflammation. Objective The aim this study was evaluate efficacy doxycycline CRSwNP. Methods In randomized, double-blind, placebo-control study, we assessed patients moderate severe A total 100 were randomly assigned...
Human astroviruses have been increasingly identified as important agents of diarrheal disease in children. Outbreaks diarrhea due to astrovirus frequently reported and also associated with nosocomial infections hospitals. A 7-year study involving 2,490 gastroenteritis samples was conducted determine the prevalence age distribution human infection well seasonality pattern 5 different cities Iran using reverse Transcriptase-polymerase chain reaction (RT-PCR). Astrovirus detected 40 2490...
Coronavirus disease 2019 (COVID-19) affects millions of people worldwide. Clinical manifestations range from asymptomatic to severe viral pneumonia. CVID patients with COVID-19 infection are not adequately studied. In some studies, had higher mortality rates, although other studies showed that might have an uncomplicated infection. We describe 14 cases in Iranian this study, including clinical manifestations, laboratory findings, and treatment strategies. There were 29% mild disease, 43%...
Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is a rare primary immunodeficiency disorder characterized by recurrent infections low immunoglobulin levels due to variable combined immunodeficiency, region dysmorphism. We describe 12-year-old boy with respiratory tract infections, anomalies, scoliosis, psychomotor retardation. He had pneumonia serum IgG IgM during infancy preschool age. Later at the age of 10, he developed ear infections. An IgA deficiency was...
Abstract Good's syndrome is a rare adult‐onset thymoma‐associated immunodeficiency with unknown pathogenesis. Therefore, it should be carefully managed as soon possible when complications are presented. Because of variety immunodeficiency, this now classified separate entity broad classification (immunodeficiency thymoma).
Abstract Background: Chronic Rhinosinusitis (CRS) is a paranasal sinus inflammatory disease and divided into two subgroups defined as CRS with nasal polyps (CRSwNP) without (CRSsNP). CRSwNP displays T helper (Th)2 biased phenotype, based on sensitivity or tolerance to aspirin non-steroidal anti-inflammatory drugs (NSAID), are further subdivided Aspirin-exacerbated respiratory (AERD) non-AERD groups. Considering the challenge of diagnosis treatment in patients CRSwNP, particularly AERD...
Background: IgA deficiency (IgAD) is the most common primary immunodeficiency, which caused by a defect in antibody production. Most of patients are asymptomatic. However, can present various manifestations. This study was designed to assess clinical and laboratory manifestations symptomatic with deficiency. Method: A group 123 referred from all over country national immunodeficiency registration center were entered followed this study. The data including demographic characteristics,...