A5005641287- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- Plant Pathogens and Fungal Diseases
- Infectious Diseases and Mycology
- Nail Diseases and Treatments
- Fungal Biology and Applications
- Laser Applications in Dentistry and Medicine
- Mycotoxins in Agriculture and Food
- Dermatologic Treatments and Research
- Mycorrhizal Fungi and Plant Interactions
- Ocular and Laser Science Research
- Social Sciences and Policies
- Peptidase Inhibition and Analysis
- Soft tissue tumor case studies
- Electromagnetic Fields and Biological Effects
- Ocular Infections and Treatments
- Vasculitis and related conditions
- Neuroendocrine Tumor Research Advances
- Ovarian cancer diagnosis and treatment
- Medical Malpractice and Liability Issues
- Cancer and Skin Lesions
- Wireless Body Area Networks
- Parasitic infections in humans and animals
- Amoebic Infections and Treatments
- Parasites and Host Interactions
Universitat Rovira i Virgili
2011-2021
Institut d'Investigació Sanitària Pere Virgili
2009-2018
Hospital Universitari Joan XXIII de Tarragona
2005-2018
Repsol (Spain)
2010
Anthrologica
1999-2008
Pathological Society
2006
Universidad de Zaragoza
2002
Hospital Universitari Sant Joan de Reus
1998
Fundación Botín
1998
Universitat de Barcelona
1986-1992
Abstract Low‐power laser radiation is currently used in the treatment of pain and osteoarticular inflammation. However, mechanisms biostimulating effects on tissue are still not completely understood. With treatment, we have achieved activation osseous regeneration human bone fractures. After 7 years positive clinical control beings, decided to start an experimental study fractures tibia mice, histologically controlling its reparation after exposure 632 nm. He/Ne doses 2.4 Joules one point...
Fungal pathogens cause disease in plant and animal hosts. The extent to which infection mechanisms are conserved between both classes of hosts is unknown. We present a dual plant-animal system based on single strain Fusarium oxysporum, the causal agent vascular wilt plants an emerging opportunistic human pathogen. Injection microconidia well-characterized tomato pathogenic isolate (isolate 4287) into lateral tail vein immunodepressed mice resulted disseminated multiple organs death animals....
Summary A murine model with immunocompetent animals was used in a comparative study of experimental pathogenicity 13 isolates belonging to the four most frequent pathogenic species Fusarium man (F. solani, F. oxysporum, verticillioides and proliferatum). Inocula 5 × 106 conidia/mouse each isolate were injected into lateral vein tail mice produce systemic infection. solani virulent species; five strains this assayed caused death all tested <19 days. The other not model. organs mainly affected...
Virulence mechanisms of the pathogenic fungus Aspergillus fumigatus are multifactorial and depend on immune state host, but little is known about fungal mechanism that develops during process lung invasion. In this study, microarray technology was combined with a histopathology evaluation infected lungs so invasion strategy followed by could be described. To achieve this, an intranasal mice infection performed to extract daily samples from over four days post-infection. The pathological...
Ten cases of cryptococcosis due to unusual microscopic forms Cryptococcus sp. observed over a twenty-eight year period (1981-2009) are presented. The most important clinicopathological and laboratory data tabulated. uncommon cryptococcal cells given are: structures resembling germ tube (one case), chains budding yeasts pseudohyphae (two cases) nonencapsulated yeast-like organisms (eight cases). diagnosis was based on the histopathological findings. causative organism isolated identified in...
The in vitro susceptibility of 17 strains Mucor circinelloides to amphotericin B and posaconazole was ascertained by using broth microdilution disk diffusion methods determining the minimal fungicidal concentration (MFC). We evaluated efficacy at 40 mg/kg body weight/day 0.8 mg/kg/day a neutropenic murine model disseminated infection M. 6 different tested previously vitro. In general, most MICs were within range or intermediate susceptibility, while small inhibition zone diameters (IZDs)...
We developed a murine model of systemic sporotrichosis by using three strains each the two commonest species causing sporotrichosis, i.e., Sporothrix schenckii sensu stricto and brasiliensis, in order to evaluate efficacy posaconazole (PSC). The drug was administered at dose 2.5 or 5 mg/kg body weight twice day gavage, one group treated with amphotericin B (AMB) as control treatment. Posaconazole, especially mg/kg, showed good against all tested, regardless their MICs, measured prolonged...
ABSTRACT We describe two cases in Brazil of human subcutaneous infections due to Phaeoacremonium spp. The first case was caused by aleophilum . patient presented with a unique fistulized nodule on the left ankle. fungus detected direct microscopic examination and isolated repeatedly from material collected lesion. This is reported infection this fungus. second rubrigenum multiple nodules around ankle foot. pus histological sections nodules. It clinical specimens. species.
Papillary neoplasms of the breast include a wide spectrum mammary lesions. The differential diagnosis benign and malignant lesions can be problematic not only cytologically, but also histopathologically. Aspiration smears demonstrate that cytological differentiation is feasible. A retrospective study 30 cases papillary tumour breast, 15 carcinomas papillomas, was performed to find differences between pathologies. Cytological samples were characterized by an abundance cellular material,...
Using a murine model of disseminated infection caused by Trichosporon asahii, we have evaluated the efficacies amphotericin B (AMB; 1 mg/kg body weight/day), fluconazole (FLC; 20 mg/kg/twice day), and micafungin (MFG; 5 day). We tested these drugs alone in combination (MFG with AMB MFG FLC). showed synergistic effect demonstrated higher degree efficacy prolonging survival reducing kidney fungal burden than either agent alone. The FLC was able to reduce significantly comparison that achieved...
ABSTRACT In the treatment of disseminated Fusarium infections, amphotericin B either alone or in combination with flucytosine and rifampin is drug therapy most frequently used. The efficacy these antifungal drugs was evaluated a murine disseminated-infection model, five strains solani . All treatments were clearly ineffective.
An experimental model of endophthalmitis by Fusarium solani in immunocompetent mice that could be useful for evaluating the efficacy different treatments and pathogenicity fungus ocular structures was established. Five clinical isolates F. were injected into lateral tail vein groups 20 mice, order to produce systemic infection with infection. Inocula 5 x 10(6) conidia per mouse used. The eyes animals died enucleated histopathological study determine degree We found fungal infections 34%...
Scedosporium prolificans is an emerging opportunist fungus that causes different types of infections in immunocompetent and immunosuppressed people. These show irregular geographical distribution and, generally, disseminated systemic are noticed only specific countries. This study used a murine model infection by this to assess if strains from origins have virulence. Two each four sources (disseminated infection, localised asymptomatic cystic fibrosis patients the environment) were tested....
We have determined the in vitro activities of amphotericin B (AMB), voriconazole, posaconazole (PSC), itraconazole (ITC), ravuconazole, terbinafine, and caspofungin against five strains Cunninghamella bertholletiae four echinulata. The best activity was shown by terbinafine both species (MIC range = 0.3 to 0.6 μg/ml) PSC 0.5 μg/ml). also evaluated efficacies PSC, ITC, AMB neutropenic diabetic murine models disseminated infection bertholletiae. at 40, 60, or 80 mg/kg body weight/day as...
Summary The efficacy of voriconazole (VRC) was evaluated against two strains each the most common species causing sporotrichosis, Sporothrix schenckii sensu stricto and brasiliensis, using a murine model disseminated infection. Voriconazole administered at doses 20 or 40 mg kg −1 per day by gavage. drug showed some efficacy, especially day, in prolonging survival reducing fungal load spleen liver mice infected with S. , whereas animals S . brasiliensis did not work.
We report a case of subcutaneous infection caused by the dermatophyte Microsporum gypseum in an immunocompetent host. The patient acquired knee through traumatic inoculation splinter. To our knowledge this is first fungus.
Autoinfective strongyloidiasis is often fatal in immunosuppressed patients or immunocomprised hosts. An interesting case of Strongyloides stercolaris hyperinfection was seen an immunocompetent patient. This report describes a strogyloidiasis 79 year old man, who had suffered gastrointestinal discomfort for years, and presented because respiratory illness. A chest radiograph showed irregular mass close to the mediastinum interstitial infiltrates, but blood eosinophilia not observed....
The tongue of the Swiss muse is rich in mast cells (MC). Tongues animals experimental group were irradiated using u He-Ne laser (2.4 J/cm2, 632 nm), and a second set unirradiated served as control. Two output powers used, with irradiation time adjusted to produce same energy dencity. possible nonselective degranulation LLLT-irradiated was examined quantitatively morphometically optic electron microscopy. By means radioimmunoassay, histamisie content pulverized evaluated, comparing levels...