Shiwen Zhou

ORCID: 0000-0003-4503-5517
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About
Contact & Profiles
Research Areas
  • Berberine and alkaloids research
  • Marine Toxins and Detection Methods
  • Marine and coastal ecosystems
  • Retinal Diseases and Treatments
  • Phytoestrogen effects and research
  • Diet, Metabolism, and Disease
  • Pancreatic function and diabetes
  • Machine Learning in Bioinformatics
  • Cannabis and Cannabinoid Research
  • Wound Healing and Treatments
  • Forensic Toxicology and Drug Analysis
  • Phytochemicals and Medicinal Plants
  • Ion channel regulation and function
  • Retinal Imaging and Analysis
  • Geological formations and processes
  • Phytochemistry and Bioactivity Studies
  • Plant-Derived Bioactive Compounds
  • Plant-based Medicinal Research
  • Diet and metabolism studies
  • Traditional Chinese Medicine Studies
  • Bioactive Compounds and Antitumor Agents
  • Biological Stains and Phytochemicals
  • Protist diversity and phylogeny
  • Clusterin in disease pathology
  • Neuropeptides and Animal Physiology

City University of Hong Kong
2020-2024

Jinan University
2017-2021

Tongji University
2015

Army Medical University
2007-2013

World Wide Web Consortium
2009

Xinqiao Hospital
2007-2008

Toads produce potent toxins, named bufadienolides, to defend against their predators. Pharmacological research has revealed that bufadienolides are potential anticancer drugs. In this research, we reported nine from the eggs of toad Bufo bufo gargarizans, including two new compounds (1 and 3). The chemical structures 1 3, as well one previously semisynthesized compound (2), were elucidated on basis extensive spectroscopic data interpretation, methods, X-ray diffraction analysis. Compound is...

10.1021/acs.jnatprod.0c00840 article EN Journal of Natural Products 2021-04-21

An actinomycete strain (H12-15) isolated from a sea sediment in mangrove district was identified as Streptomycesantibioticus on the basis of 16S rDNA gene sequence analysis well investigation its morphological, physiological, and biochemical characteristics. Two novel benzamido nonacyclic dilactones, namely neoantimycins A (1) B (2), together with known antimycins A1ab (3a,b), A2a (4), A₉ (5), were culture broth this strain. Compounds 1 2 are first natural modified ATNs an unusual benzamide...

10.3390/molecules22040557 article EN cc-by Molecules 2017-03-30

Ciguatera is one of the most widespread food poisonings caused by ingestion fish contaminated ciguatoxins (CTXs). Snapper and grouper with high palatable economic value are primary source species for exportation in Republic Kiribati, but they highly suspected CTX-contaminated due to their top predatory characteristics. In this study, 60 specimens from 17 snappers groupers collected Kiritimati Island Marakei Kiribati were analyzed using mouse neuroblastoma (N2a) assay liquid...

10.3390/toxins14030208 article EN cc-by Toxins 2022-03-15

Numerous recent studies suggest that abnormal intracellular calcium concentration ([Ca2+]i) is a common defect in diabetic animal models and patients. Abnormal handling an important mechanism the defective pancreatic β-cell function type 2 diabetes. T-type Ca2+ channel antagonists lower blood glucose diabetes, but remains unknown.We examined effect of antagonist mibefradil on male db/db mice phenotypically normal heterozygous by intraperitoneal injection.Mibefradil (15 mg/kg, i.p., b.i.d.)...

10.6061/clinics/2014(01)09 article EN cc-by-nc Clinics 2013-12-27
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