- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Sesquiterpenes and Asteraceae Studies
- Natural product bioactivities and synthesis
- Traditional and Medicinal Uses of Annonaceae
- Psidium guajava Extracts and Applications
- Plant chemical constituents analysis
- Insect Pest Control Strategies
- Plant biochemistry and biosynthesis
- Botanical Research and Applications
- Plant Toxicity and Pharmacological Properties
- Phytochemical compounds biological activities
- Phytochemicals and Antioxidant Activities
- Bioactive Natural Diterpenoids Research
- Allelopathy and phytotoxic interactions
- Phytochemicals and Medicinal Plants
- Plant Pathogens and Fungal Diseases
- Phytochemistry and Bioactivity Studies
- Plant-Derived Bioactive Compounds
- Phytochemistry Medicinal Plant Applications
- Phytochemistry and Bioactive Compounds
- Piperaceae Chemical and Biological Studies
- Biological Activity of Diterpenoids and Biflavonoids
- Natural Compound Pharmacology Studies
- Ethnobotanical and Medicinal Plants Studies
University of the Coast
2025
University of the Andes
2015-2024
Universidad de Los Andes
2008-2023
Universidad de Ciencias Médicas de Villa Clara
2019
Universidad de Ciencias Medicas
2019
Instituto de Investigaciones en Ciencias de la Salud
2011-2016
Bolivarian University of Venezuela
2015
Academia Nacional de Medicina Venezuela
2015
Universidad de Los Andes
2001-2014
Universidad Católica Andrés Bello
2012
Abstract Origanum majorana L. (Lamiaceae) is a plant that used in gastronomy and natural medicine. The material this study was collected at San Isidro de Apartaderos, Mérida State. A yield of 0.6% essential oil obtained by hydro-distillation using Clevenger trap. main constituents found were: cis-sabinene hydrate (30.2%), terpinen-4-ol (28.8%), γ-terpinene (7.2%), α-terpineol (6.9%), trans-sabinene (4.4%), linalyl acetate (3.8%), α-terpinene (3.6%). also fractionated over silica gel dry...
En este artículo se lleva a cabo la investigación de los factores sociodemográficos asociados con incidencia lesiones musculoesqueléticas (LME) el personal enfermería del área urgencias una IPS ciudad Barranquilla. Esta define como objetivo determinar correlación entre variables sociodemográficas y manifestación musculoesqueléticas; para ello utilizó un diseño relacional aplicando cuestionario nórdico estandarizado 26 enfermeros. muestra, seleccionaron hombres mujeres asistencial al que le...
The global phenolic content of argan oil and press cake samples (alimentary cosmetic) was evaluated using the Folin−Ciocalteu colorimetric method composition (alimentary) were analyzed by GC-MS after extraction with 80:20 (v/v) methanol:water silylation. Identification chromatographic peaks made mass selective detection. Nineteen simple phenols detected, 16 in cake, 6 alimentary oil, 7 cosmetic among which 15 compounds [3-hydroxypyridine (3-pyridinol), 6-methyl-3-hydroxypyridine, catechol,...
Abstract Eryngium foetidum is a perennial herb native to tropical America whose leaves are used as food seasoning. The aerial parts of this plant were hydrodistilled and the essential oil was collected in Clevenger-type trap. analyzed by GC GC/MS. main constituents 2,4,5-trimethyl-benzaldehyde (27.7%), (E)-2-dodecenal (27.5%), carotol (8.8%), 3-dodecenal (5.2%) γ-terpinene (3.8%).
The use of medicinal plants for AIDS-related conditions is common in South Africa. In order to establish an antiviral rationale the these we screened fractions methanol extracts activity against HIV-1 reverse transcriptase (RT) and integrase (IN). n-butanol fraction obtained from crude roots Bridelia micrantha (Hochst) Baill. (Euphorbiaceae) was observed be as most active inhibiting RNA-dependent-DNA polymerization (RDDP) RT with IC50 7.3 �g/ml. However, it had no on 3’-end processing HIV...
<h3>Objective</h3> Resection of primary colorectal cancer is associated with enhanced risk development liver metastases. It was previously demonstrated that surgery initiated an early inflammatory response resulting in elevated tumour cell adhesion the liver. Because reactive oxygen species (ROS) are shown to be produced and released during surgery, effects ROS on vascular lining were investigated. <h3>Methods</h3> Human endothelial monolayers (human umbilical vein cells (HUVECs) human...
The essential oil of Cordia verbenacea D.C. (Boraginaceae) that grows in Mérida-Venezuela was obtained by hydrodistillation from the aerial parts plant, yielding 0.21%. analyzed GC-FID and GC-MS. Thirty one components which made up 94.3% were identified. most abundant constituents found were: tricyclene (23.9%), bicyclogermacrene (11.7%), germacrene D (9.9%) beta-caryophyllene (8.2%). Antibacterial activity determination carried out according to disc diffusion assay. Activity against...
The essential oil from aerial parts of Conyza bonariensis (L) Cronquist collected in Mérida was obtained by hydrodistillation and analysed GC/MS. major components were trans-beta-farnesene (37.8%), trans-ocimene (20.7%) beta-sesquiphellandrene (9.8%). Cytotoxicity assay also performed with the against HeLa (cervix carcinoma), A-459 (lung carcinoma) MCF-7 (breast adenocarcinoma) human cell lines normal Vero cells (African green monkey kidney) IC50 values ranging 1.4 to 45.8 microg/mL....
The essential oil obtained from the leaves of Lantana camara var. moritziana (Otto & Dietr.) López-Palacios collected at Rubio, Táchira State, Venezuela, was by hydrodistillation in a Clevenger trap (0.1% yield). analyzed gas chromatography-mass spectrometry (GC/MS) on HP GC-MS System, model 5973, identifying 33 compounds (97.1%) which major components were germacrene D (31.0%), followed beta-caryophyllene (14.8%), a-phellandrene (6.7%), limonene (5.7%) and 1,8-cineole (5.2%). Evaluation...
The essential oil of Satureja brownei (SW.) Briq., was studied by GC and GC–MS. A yield 0.12% (v/w) obtained. main constituents found were pulegone (64.3%), menthone (20.2%), isomenthone (3.4%) isopulegone (2.4%). Copyright © 2000 John Wiley & Sons, Ltd.
Chemical constituents of the essential oil from leaves Minthostachys mollis (Kunth) Griseb Vaught var. collected in January 2008 at Tuñame, Trujillo State, Venezuela, were separated and identified by GC-MS analysis. The was obtained hydrodistillation thirteen components (98.5% sample) comparison with Wiley library data base. two major pulegone (55.2%) trans-menthone (31.5%). showed a significant inhibitory effect against Gram-positive Gram-negative bacteria, especially Bacillus subtilis...
Abstract Two new triterpenoid glycosides, together with two ergostane umbellatosides A–D ( 1 – 4 , resp.), have been isolated from the leaves of Hydrocotyle umbellata L. Their structures were established by 2D‐NMR spectroscopic techniques H, H‐COSY, TOCSY, NOESY, HSQC, and HMBC) mass spectrometry as 3 β ,22 ‐dihydroxy‐3‐ O ‐[ α ‐ L ‐rhamnopyranosyl‐(1→2)‐ D ‐glucuronopyranosyl]olean‐12‐en‐28‐oic acid 28‐ ‐glucopyranosyl ester ), 3‐ ‐glucuronopyranosyl]oleanolic 2 (3 ,11...
Hydrodistillation of Vismia macrophylla Kunth (Hypericaceae) leaves (L) and fruits (F) yielded 1.3%, v/w, 5.6%, essential oil, respectively. GC GC-MS analyses showed the presence twenty-four (96.4%, L) thirty-one (96.6%, F) components, Major compounds identified in leaf oil were γ-bisabolene (44.4%) β-bisabolol (14.9%), while those fruit germacrene-D (12.1%), 6-cadinene (10.7%) (22.3 %). Oil obtained from V. antibacterial activity against Gram-positive (S. aureus ATCC 25923 E. faecalis...
The essential oil of the leaves Espeletia nana Cuatrec., obtained by hydrodistillation, was analyzed GC-MS, which allowed identification 24 components, made up 99.9% oil. most abundant compounds were a-pinene (38.1%), beta-pinene (17.2%), myrcene (15.0%), spathulenol (4.2%), bicyclogermacrene (4.0%), a-zingiberene and gamma-himachalene (3.7%). Antibacterial activity tested against Gram-positive Gram-negative bacteria using agar disk diffusion method. Activity observed only bacteria. MIC...
The essential oils from fresh aerial parts of Monticalia greenmaniana (Hieron) C. Jeffrey (Asteraceae) collected in March, were analyzed by GC/MS. Oil yields (w/v) 0.1% (flowers), 0.07%, (stems) and (leaves) obtained hydrodistillation. Thirteen, sixteen eighteen components, respectively, identified comparison their mass spectra with those the Wiley GC-MS Library data base. major components flower stem 1-nonane (38.8% flowers; 33.5% stems), alpha-pinene (29.0% 14.8% stems) germacrene D (15.6%...
The leaves and inflorescences of five species Tagetes, family Asteraceae, were collected from different locations in Mérida state, Venezuela, their essential oils analyzed by GC GC/MS. Several differences observed the composition these oils, mainly regarding major components, which for T. caracasana trans-ocimenone (64.3%) cis-tagetone (13.7%), erecta, piperitone (35.9%) terpinolene (22.2%). High amounts trans-anethole (87.5%) estragole (10.7%) filifolia, while subulata oil contained...
Apis mellifera bees obtain propolis by adding wax and salivary secretions to resinous, gummy or balsamic materials collected from various plant sources. Its chemical composition depends on many factors (type of bee, flora accessed, environment, management, season, vegetation geographical area collection). In the hive, use consolidate structural components, varnish inside cells prevent vibrations. Propolis is known for its antibacterial, fungicidal, antiviral, anesthetic, antiulcer,...
The essential oil obtained by hydrodistillation of Carapa guianensis Aubl. (Meliaceae) leaves was analyzed GC-FID and GC-MS. Twenty-three components were identified, which made up 93.7% the oil. most abundant constituents bicyclogermacrene (28.5%), alpha-humulene (17.2%), germacrene B (11.9%), trans-beta-caryophyllene (9.9%). Antimicrobial activity oil, as well crude extracts refluxing dried with n-hexane, dichloromethane, methanol, determined using disc diffusion assay. Activity against...