Zhongwen Zhi

ORCID: 0000-0003-4510-8966
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About
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Research Areas
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Fluoride Effects and Removal
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Nanoplatforms for cancer theranostics
  • Circular RNAs in diseases
  • RNA Research and Splicing

Second People’s Hospital of Huai’an
2019-2022

Xuzhou Medical College
2019-2022

Lianyungang Oriental Hospital
2022

Nanjing Medical University
2022

Kangda College of Nanjing Medical University
2022

Introduction. To investigate the function of miR-190a-3p on proliferation and migration glioma. Methods. Twenty glioma samples 6 normal brain tissue were collected. Normal human glial cell line HEB lines used for experiments. We then TargetScan to predict target genes miR-190a-3p. Dual-luciferase reporter assay was also validate. Results. Combined with dual-luciferase experiment, we finally verified that YOD1 aim, it low-expressed in Besides, a series mechanism experiments proved negatively...

10.1155/2021/3957738 article EN cc-by Computational and Mathematical Methods in Medicine 2021-09-04

Abstract 2-(2-benzofu-ranyl)-2-imidazoline (2-BFI) is a drug that has attracted much attention in recent years. It therapeutic effect on brain diseases such as Alzheimer’s disease and cerebral infarction. However, whether 2-BFI affects the proliferation of cells exposed to fluoride not known. We investigated apoptosis SH-SY5Y fluoride, was used protect against effects fluoride. found could enhance upon fluorosis by maintaining stability endoplasmic reticulum–mitochondria contact sites...

10.21203/rs.3.rs-1624745/v1 preprint EN cc-by Research Square (Research Square) 2022-05-09
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