Andrew L Alejo

ORCID: 0000-0003-4532-1900
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About
Contact & Profiles
Research Areas
  • Trauma and Emergency Care Studies
  • Traffic and Road Safety
  • Osteoarthritis Treatment and Mechanisms
  • Musculoskeletal pain and rehabilitation
  • Lymphatic System and Diseases
  • Infectious Diseases and Tuberculosis
  • Patient Satisfaction in Healthcare
  • Hip and Femur Fractures
  • Ethics in Clinical Research
  • Resilience and Mental Health
  • Orthopaedic implants and arthroplasty
  • Salmonella and Campylobacter epidemiology
  • Inflammatory mediators and NSAID effects
  • Parvovirus B19 Infection Studies
  • Infections and bacterial resistance
  • Neonatal Respiratory Health Research
  • Social Media in Health Education
  • Dupuytren's Contracture and Treatments
  • Neurological and metabolic disorders
  • Cancer Diagnosis and Treatment
  • Biomarkers in Disease Mechanisms
  • Migration, Health and Trauma
  • Spine and Intervertebral Disc Pathology
  • Kawasaki Disease and Coronary Complications
  • Lipoproteins and Cardiovascular Health

Case Western Reserve University
2023-2024

Northeast Ohio Medical University
2021-2024

Stony Brook University Hospital
2024

University Hospitals of Cleveland
2023

MetroHealth Medical Center
2023

Creative Commons
2023

MetroHealth
2023

Orthopaedic Trauma Association
2023

Ohio University
2023

Summa Health System
2023

Health literacy is often poor among trauma patients. We introduced an educational mobile application to newly injured hypothesized that patients who utilized the app would be more informed about their injury and treatment recommendations, users demonstrate greater adherence recommendations.Prospective, cohort study.Level 1 centerPatients/participants: Adult with acute orthopaedic injury.App information injuries, treatment, recovery. bit.ly/traumaapp.Survey regarding knowledge...

10.1097/bot.0000000000002677 article EN Journal of Orthopaedic Trauma 2023-07-25

A psoas abscess is a rare infection; it an accumulation of purulent material within the muscle. Common pathogens include Staphylococcus aureus, streptococci, Escherichia coli, and other enteric Gram-negative bacilli anaerobes. These abscesses are thought to occur by either hematogenous spread, contiguous spread from adjacent organs, trauma, or local inoculation. Pasteurella multocida pathogen that usually infects patient via bite scratch dogs cats causes cellulitis at site injury. may also...

10.7759/cureus.39376 article EN Cureus 2023-05-23

Orthopaedic trauma patients may experience poor recall regarding their injury and treatment, impairing postoperative outcomes. We sought to evaluate the impact of a standardized educational protocol on patient recall, adherence treatment plan, satisfaction.

10.2106/jbjs.23.01366 article EN Journal of Bone and Joint Surgery 2024-08-27

Resiliency consists of three core components, which include presence adversity, protective factors to overcome and positive outcomes or growth. Therefore, resiliency aligns with the trauma recovery process. This paper describes development Trauma Scale (tRS) quantify patients upon presentation during recovery. items were proposed reviewed by an expert panel. Group construct validity testing was performed using both individual focus group feedback item analysis. Reliability measured...

10.1002/jor.25550 article EN Journal of Orthopaedic Research® 2023-03-15

No guidelines exist for recommending return to driving. This study will examine time brake (TTB) after lower extremity injuries versus in uninjured people. The potential effect of various types on TTB be measured.Patients with the pelvis, hip, femur, knee, tibia, ankle, and foot underwent testing using a driving simulator assess TTB. Comparison was control group people.Two-hundred thirty-two patients participated. majority were tibia ankle regions (47%). Mean subjects 0.74 seconds, compared...

10.5435/jaaosglobal-d-23-00018 article EN cc-by-nc-nd JAAOS Global Research and Reviews 2023-04-01

Osteoarthritis (OA) is a debilitating degenerative joint disease that results in chronic pain and inflammation due to progressive mechanical proteolytic cartilage degradation. Articular chondrocytes, the main cell type present cartilage, are responsible for deposition maintenance of extracellular matrix (ECM). However, following damage inflammation, chondrocytes undergo hypertrophy, apoptosis, contribute ECM NF-κB signaling known be dysregulated OA. TRAPPC9, vesicle trafficking protein,...

10.20944/preprints202304.0432.v1 preprint EN 2023-04-17

Non-ketotic hyperglycemia is an uncommon cause of hemichorea-hemiballismus syndrome that has been associated with high levels glucose are not well controlled. Lesions typically occur in the globus pallidus and putamen, which can be identified via computed tomography (CT) or magnetic resonance imaging (MRI). These lesions generally correspond ballistic choreiform movements on contralateral side observed findings. Additionally, amelioration first-line treatment usually reduces resolves these...

10.7759/cureus.38434 article EN Cureus 2023-05-02

The rat animal model is a cost effective and reliable used in spinal pre-clinical research. Complications from various surgical procedures humans often arise that were based on these models. Therefore safe efficacious models are needed to establish continuity into clinical trials. A Standard Operating Procedure (SOP) validated method allows researchers safely carefully replicate previously successful techniques. Thus, the aim of this study describe detail involved common bilateral...

10.26502/josm.511500060 article EN Journal of Orthopaedics and Sports Medicine 2022-01-01

Pulmonary pleomorphic carcinoma (PPC) is a subtype of non-small cell lung cancer that extremely rare and carries poor prognosis due to its inadequate response treatment. Patients present with PPC often exhibit similar symptoms other malignancies the lung, making it hard for clinicians distinguish between each type. However, cytology gene mutation testing are two approaches can aid physicians in an accurate definitive diagnosis. We case 88-year-old male patient diagnosis pulmonary after...

10.7759/cureus.37860 article EN Cureus 2023-04-20

Drug-induced lupus (DIL) usually presents after starting a medication known to induce DIL. However unusual presentations are rare, as such, our patient presented with initial signs and symptoms of pericarditis. Once treated he progressively declined angioedema worsening cardiopulmonary status. On first admission, the chest pain that was worsened by laying down improved sitting up. CT Angiography (CTA) showed mild pericardial effusion, EKG diffuse ST elevation, both suggestive pericarditis,...

10.7759/cureus.38376 article EN Cureus 2023-05-01

The current standard of evaluating septic arthritis in the emergency department involves arthrocentesis analysis and culture. Culture results can then help guide pathogen specific treatment. Without prompt treatment arthritis, joint undergoes irreversible destruction leading to chronic pain need for surgical replacement. Therefore, we propose an additional method process using ultrasound imaging order evaluate certain findings that could be used diagnose without having undergo procedures....

10.26502/josm.511500099 article EN Journal of Orthopaedics and Sports Medicine 2023-01-01

Acute monocytic leukemia (AML), a subtype of acute myeloid leukemia, is rare found in children. It occurs more frequently adults over the age 60. Myocarditis represents inflammation muscular layer heart, myocardium causing weakening muscles that can lead to hemodynamic instability from reduced ejection fraction. pediatric population most commonly secondary viral or infectious etiology. Hemophagocytic lymphohistiocytosis (HLH) condition immune dysregulation characterized by severe organ...

10.7759/cureus.39147 article EN Cureus 2023-05-17

Transjugular intrahepatic portosystemic shunt (TIPS) procedures are commonly performed in patients with cirrhosis to decrease the pressure portal system. An unusual complication of this procedure is endotipsitis, an infection shunt/stent resultant sustained bacteremia caused by vegetation within TIPS. The most associated pathogens include staphylococci, enterococci, streptococci, and enteric Gram-negative bacilli. We present a patient who developed endotipsitis due Klebsiella pneumoniae...

10.7759/cureus.39259 article EN Cureus 2023-05-20

Exposing children to numerous radiographs in order diagnose various musculoskeletal injuries is not ideal due the deleterious side effects of ionizing radiation on growth plates. In particular, Little Leaguer’s Shoulder a common pediatric and adolescent injury that relies mainly recognize treat. Thus, if other imaging modalities without radiation, such as ultrasound, can be shown reliable accurate measuring humeral physeal width, it may serve better means identifying these injuries. The...

10.26502/josm.511500109 article EN Journal of Orthopaedics and Sports Medicine 2023-01-01

Complex lymphatic anomalies (CLAs) are a set of rare diseases with unique osteopathic profiles. Recent efforts have identified how lymphatic-specific somatic activating mutations can induce abnormal formations that capable invading bone and inducing resorption. The resorption in CLA patients has been linked to overactive osteoclasts areas invasions. Despite these findings, the mechanism associated progressive loss CLAs remains be elucidated. In order determine role osteoblasts CLAs, we...

10.3390/cells12202482 article EN cc-by Cells 2023-10-18
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