A5001886056- Ophthalmology and Eye Disorders
- Cerebral Venous Sinus Thrombosis
- Glaucoma and retinal disorders
- Ocular Diseases and Behçet’s Syndrome
- Intracranial Aneurysms: Treatment and Complications
- Retinal and Optic Conditions
- Pituitary Gland Disorders and Treatments
- Trigeminal Neuralgia and Treatments
- Migraine and Headache Studies
- Vasculitis and related conditions
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Retinal Development and Disorders
- Neurosurgical Procedures and Complications
- Sarcoidosis and Beryllium Toxicity Research
- Drug-Induced Ocular Toxicity
- Intraoperative Neuromonitoring and Anesthetic Effects
- Medical and Biological Sciences
- Vestibular and auditory disorders
- Neurofibromatosis and Schwannoma Cases
- Mitochondrial Function and Pathology
- Fetal and Pediatric Neurological Disorders
- Head and Neck Surgical Oncology
- Peripheral Neuropathies and Disorders
Cleveland Eye Clinic
2003-2020
Cleveland Clinic
2007-2020
The California Eye Institute
2019
Cleveland Research (United States)
2000-2017
Kent State University at Ashtabula
2011
Eye Center
2001
Oncology Hematology Care
1999
Cincinnati Eye Institute
1999
University of Cincinnati
1999
Cleveland Foundation
1993-1997
Abstract Objective To evaluate treatment with methotrexate (MTX) in patients newly diagnosed giant cell arteritis (GCA) to determine if MTX reduces GCA relapses and cumulative corticosteroid (CS) requirements diminishes disease‐ treatment‐related morbidity. Methods This was a multicenter, randomized, double‐blind study. Over 4 years, 16 centers from the International Network for Study of Systemic Vasculitides enrolled unequivocal GCA. The initial 1 mg/kg/day (≤60 mg every day) prednisone,...
Article abstract-Ten patients with migraine developed persistent positive visual phenomena lasting months to years. The complaints were similar in their simplicity and involvement of the entire field usually consisted diffuse small particles such as TV static, snow, lines ants, dots, rain. Neurologic ophthalmologic examinations normal, EEGs normal eight tested. MRI was all except one who had nonspecific biparietal white matter lesions another a venous angioma. Treatment this unusual...
We conducted a masked, crossover, therapeutic trial of gabapentin (1,200mg/day) versus memantine (40 mg/day) for acquired nystagmus in 10 patients (aged 28-61 years; 7 female; 3 multiple sclerosis [MS]; 6 post-stroke; 1 post-traumatic). Nystagmus was pendular (4 oculopalatal tremor; 2 MS) and jerk upbeat, hemi-seesaw, torsional, or upbeat-diagonal each the others. For group, both drugs reduced median eye speed (p < 0.001), by 32.8% 27.8%, improved visual acuity 0.05). Each patient with...
Surgical outcome has been less than desirable in the management of patients with clinoidal meningiomas past, and little attention directed at improving their visual function. The purpose this article is to advocate an available cranial base technique for removing these difficult tumors delineate technique's advantages that aid achieving improved extent tumor resection enhancing patients' overall outcome, particularly outcome.A retrospective analysis was performed on 15 consecutive (including...
<h3>Objective.</h3> —To assess the safety and efficacy of optic nerve decompression surgery compared with careful follow-up alone in patients nonarteritic anterior ischemic neuropathy (NAION). <h3>Design.</h3> —The Ischemic Optic Neuropathy Decompression Trial (IONDT) is a randomized, single-masked, multicenter trial. <h3>Setting.</h3> —Twenty-five US clinical centers. <h3>Participants.</h3> IONDT ceased recruitment on October 20, 1994, recommendation its Data Safety Monitoring Committee....
To characterize the neuro-ophthalmologic manifestations of impaired cranial venous outflow.A retrospective study 20 patients who developed increased intracranial pressure as result cerebral drainage.Three referral centers.Ten had noncompressive thrombosis sagittal or lateral sinuses (noncompressive group), four compression sinus jugular veins (compressive and six transient following surgical procedures (iatrogenic group).Medical and/or treatment underlying conditions predisposing to...
Recently developed anti-tumour therapies targeting immune checkpoints include tremelimumab and durvalumab. These agents have incompletely characterised side effect profiles. The authors report a 68-year-old man treated for non-small cell lung cancer (NSCLC) with combination of After treatment he diplopia, ptosis, fatigue, weakness, an inflammatory myopathy affecting the extraocular muscles requiring hospitalisation. Electromyography (EMG) testing muscle biopsy suggested without sign...
A role for microorganisms in giant cell arteritis (GCA) has long been suspected. We describe the microbiomes of temporal arteries from patients with GCA and controls.Temporal artery biopsies suspected to have were collected under aseptic conditions snap-frozen. Fluorescence situ hybridization (FISH) long-read 16S rRNA-gene sequencing was used examine arteries. Taxonomic classification bacterial sequences performed genus level relative abundances calculated. Microbiome differential analyzed...