A5049441963- Ion-surface interactions and analysis
- Mass Spectrometry Techniques and Applications
- Analytical chemistry methods development
- Photochemistry and Electron Transfer Studies
- Molecular Junctions and Nanostructures
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Perovskite Materials and Applications
- Spectroscopy and Quantum Chemical Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Thermodynamics and Statistical Mechanics
- Electrochemical Analysis and Applications
- Protein Structure and Dynamics
- Computational Drug Discovery Methods
- Polymer Surface Interaction Studies
- RNA and protein synthesis mechanisms
- Advanced Chemical Physics Studies
- Various Chemistry Research Topics
- Integrated Circuits and Semiconductor Failure Analysis
- Phase Equilibria and Thermodynamics
- Metabolomics and Mass Spectrometry Studies
- Machine Learning in Bioinformatics
- Quantum Dots Synthesis And Properties
- Electrocatalysts for Energy Conversion
- Material Dynamics and Properties
University of Washington
2015-2025
Perkins School for Blind
2025
Seattle University
2015-2020
Oakwood Laboratories (United States)
2020
Colorado State University
2020
Colorado School of Public Health
2020
Loyola University Chicago
2007-2019
Fred Hutch Cancer Center
2018
Harvard University
2014-2015
Molecular Sciences Institute
2015
Abstract Organic–inorganic perovskites such as CH 3 NH PbI are promising materials for a variety of optoelectronic applications, with certified power conversion efficiencies in solar cells already exceeding 21%. Nevertheless, state-of-the-art films still contain performance-limiting non-radiative recombination sites and exhibit range complex dynamic phenomena under illumination that remain poorly understood. Here we use unique combination confocal photoluminescence (PL) microscopy chemical...
The surfaces of six biologically interesting calcium phosphate (CaP) phases (hydroxyapatite, dibasic dihydrate, phosphate, monobasic β-tribasic octacalcium phosphate) have been examined by X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (TOF-SIMS). intensity an O(1s) shake-up satellite correlates with the oxygen content. Together Ca/P O/Ca XPS peak ratios, this feature helps provide identification CaP phase(s) present in surface unknown samples...
Abstract This work compares the removal of bovine aortic endothelial cell (BAEC) monolayers via 1) low‐temperature liftoff from a “smart polymer,” plasma polymerized poly( N ‐isopropyl acrylamide) (ppNIPAM), 2) enzymatic digestion, and 3) mechanical dissociation ppNIPAM surfaces. We examine surfaces after by using X‐ray photoelectron spectroscopy (XPS), time‐of‐flight secondary ion mass spectrometry (ToF‐SIMS), immunostaining, adhesion assay. Immunoassay results indicate that...
Abstract Electrochemical energy-storage devices have the potential to be clean and efficient, but their current cost performance limit use in numerous transportation stationary applications. Many organic molecules are abundant, economical electrochemically active; if selected correctly rationally designed, these offer a promising route expand applications of devices. In this study, polycyclic aromatic hydrocarbons introduced within functionalized few-walled carbon nanotube matrix develop...
Humid atmosphere annealing enhances interdiffusion in sequentially evaporated perovskites, leading to improved crystallinity and reduced non-radiative recombination. This boosts PLQY raises PCE 21.0%, while enhancing stability under 85 °C full-spectrum illumination.
The temperature-responsive behavior of poly(N-isopropyl acrylamide) (pNIPAM) directly affects the attachment and detachment cells cultured on these surfaces. At culture temperatures, behave similarly to those tissue polystyrene (TCPS), while at room temperature, pNIPAM spontaneously detach as a confluent sheet. In comparison, grown TCPS remain attached indefinitely after temperature drop, requiring enzymatic or mechanical removal. this work, we present an examination response bovine aortic...
Proper display of three-dimensional time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging data complex, nonflat samples requires a correction the in z-direction. Inaccuracies displaying ToF-SIMS arise from projecting surface onto 2D image plane, as well possible variations sputter rate sample being probed. The current study builds on previous studies by creating software written Matlab, ZCorrectorGUI (available at http://mvsa.nb.uw.edu/), to apply z-correction entire 3D sets....
Boxing in Peroxide Hydrogen peroxide (H 2 O ) is a powerful oxidant, and its reactivity exploited numerous biological, as well synthetic, contexts. Lopez et al. (p. 450 have now managed to capture dianion (O 2- cryptand—essentially molecular box assembled from benzamide derivatives—keeping the stable organic solution for days through net of well-placed internal hydrogen-bond donors. The encapsulated exhibited clean oxidative back either by chemical or electrochemical means.
The ability to control proton translocation is essential for optimizing electrocatalytic reductions in acidic solutions. We have synthesized a series of new hangman iron porphyrins with hanging groups differing proton-donating abilities and evaluated their hydrogen-evolving using foot-of-the-wave analysis. In the presence excess triphenylphosphine, initiate reduction electrocatalysis upon FeI. By changing group, we can affect rate catalysis by nearly 3 orders magnitude. an acid/base moiety...
Self-assembled monolayers (SAMs) of dodecanethiol on gold formed by solution assembly and microcontact printing were compared using electron spectroscopy for chemical analysis (ESCA) time-of-flight secondary ion mass spectrometry (SIMS). Both univariate (ESCA TOF-SIMS) multivariate (TOF-SIMS) techniques employed. Univariate showed that samples stamped with a thiol concentration >10−50 mM produced SAMs comparable to long times. Principal component (PCA) the SIMS spectra provided deeper...
In the past decade, temperature-responsive behavior of poly(N-isopropyl acrylamide) (pNIPAM) has come to be recognized as a convenient method for nondestructive harvest confluent cell layers. Recently, we have utilized this means ascertain nature extracellular matrix (ECM) secreted from cells. work, compare ECM obtained after liftoff individual proteins adsorbed directly onto RF-plasma-deposited pNIPAM (ppNIPAM). Using X-ray photoelectron spectroscopy, find that composition ppNIPAM post-cell...
Thorough studies of protein interactions with stimulus responsive polymers are necessary to provide a better understanding their applications in biosensors and biomaterials. In this study, behavior on thermoresponsive polymer surface, plasma polymerized N-isopropyl acrylamide (ppNIPAM), is investigated using multiple characterization techniques above below its lower critical solution temperature (LCST). Protein adsorption binding affinity probed radiolabeled proteins. activity estimated by...
In time-of-flight secondary ion mass spectrometry (ToF-SIMS), the choice of primary used for analysis can influence resulting spectrum. This is because different types produce fragmentation pathways. this study, single-component protein monolayers were performed using monatomic, tri-atomic, and polyatomic sources. Eight ions (Cs(+), Au(+), Au(3) (+), Bi(+), Bi(3) (++), C(60) (+)) to examine low (m/z < 200) patterns from five proteins (bovine serum albumin, bovine fibrinogen, immunoglobulin G...
The splitting of water into its constituent elements is an important solar fuels conversion reaction for the storage renewable energy. For each half reactions oxygen evolution (OER) and hydrogen (HER), multiple protons electrons must be coupled to avoid high-energy intermediates. To understand mechanistic details PCET chemistry that underpins HER OER, we have designed hangman porphyrin corrole catalysts. In these constructs, a pendant acid/base functionality within secondary coordination...
We report the results of a VAMAS (Versailles Project on Advanced Materials and Standards) interlaboratory study measurement composition in organic depth profiling. Layered samples with known binary compositions Irganox 1010 either 1098 or Fmoc-pentafluoro-l-phenylalanine each layer were manufactured single batch distributed to more than 20 participating laboratories. The analyzed using argon cluster ion sputtering X-ray photoelectron spectroscopy (XPS) time-of-flight secondary mass...
The Pd(I)−Pd(I) dimer [(FPNP)Pd−]2 reacts with O2 upon exposure to light produce either the superoxide (FPNP)PdO2 or peroxide [(FPNP)PdO−]2, which exist in equilibrium free O2. Both complexes contain square-planar Pd(II) centers. unpaired electron density is localized on ligand.