Yu Zhang

ORCID: 0000-0003-4576-9385
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About
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Research Areas
  • Viral gastroenteritis research and epidemiology
  • Retinal Diseases and Treatments
  • Respiratory viral infections research
  • Viral Infections and Immunology Research
  • Ocular Oncology and Treatments
  • Acne and Rosacea Treatments and Effects
  • Organic Light-Emitting Diodes Research
  • Ocular Diseases and Behçet’s Syndrome
  • Ocular Surface and Contact Lens
  • Intravenous Infusion Technology and Safety
  • Animal Virus Infections Studies
  • RNA regulation and disease
  • Retinoids in leukemia and cellular processes
  • Infectious Encephalopathies and Encephalitis
  • Ocular Infections and Treatments
  • Head and Neck Surgical Oncology
  • Bladder and Urothelial Cancer Treatments
  • Lanthanide and Transition Metal Complexes
  • Glaucoma and retinal disorders
  • Dendrimers and Hyperbranched Polymers
  • Carbohydrate Chemistry and Synthesis
  • Trypanosoma species research and implications
  • Surface Modification and Superhydrophobicity
  • Lysosomal Storage Disorders Research
  • Dermatologic Treatments and Research

Qingdao Municipal Hospital
2013-2022

Qingdao University
2013-2022

Health First
2018

The increased proliferation and migration of airway smooth muscle cells (ASMCs) are critical processes in the formation remodeling asthma. Long non-coding RNAs (lncRNAs) have emerged as key mediators diverse physiological pathological processes, involved pathogenesis various diseases, including LncRNA Malat1 has been widely reported to regulate multiple cell types be human diseases. However, it remains unknown whether regulates ASMC migration. Here, we explored function vitro stimulated by...

10.3389/fphys.2019.01337 article EN cc-by Frontiers in Physiology 2019-10-22

Because of the higher conservation RSV Fusion (F) protein than glycoprotein (G) across strains and serotypes, majority vaccine candidates targets to viral fusion rather elicit a broader range protective neutralizing antibodies from infection. In this study, we screened two chemically modified mRNA vaccines expressing prefusion stabilized (preF) targeting A2 B subtypes. After immunization, antigen-specific binding antibody, T cell-mediated immune response were evaluated. challenge with live...

10.3389/fimmu.2025.1542592 article EN cc-by Frontiers in Immunology 2025-03-24

Purpose: Vogt-Koyanagi-Harada (VKH) is an autoimmune disease with bilateral granulomatous uveitis and various systemic manifestations. Bilateral acute angle closure glaucoma (AACG) can be a rare initial manifestation of VKH that may misdiagnosed as primary (PACG). Case report: A 62-year-old woman painless loss vision referred to Qingdao Municipal Hospital. She had been diagnosed PACG before admission prescribed anti-glaucoma treatment which did not improve her symptom. severe uveitis, optic...

10.1177/1120672120951442 article EN European Journal of Ophthalmology 2020-08-18

Abstract Mutations in ATP6 gene are frequent causes of mitochondrial encephalomyopathies. encodes one subunit complexⅤ. The present study described a missense mutation 8‐year‐old Chinese boy with encephalomyopathy. We identified (m.8914C>T) by DNA sequencing. This altered the amino acid proline serine, and alterative protein is predicted to be harmful. load blood sample patient 59.49%. Activity all complexes normal, however, total function oxidative phosphorylation were declined...

10.1016/j.ijdevneu.2018.09.007 article EN International Journal of Developmental Neuroscience 2018-09-28

BACKGROUND:We assessed the potential association between monocyte chemotactic protein 1 (MCP-1) variants (rs1024611 and rs3760396) age-related macular degeneration (AMD) susceptibility among Chinese Han people. MATERIAL AND METHODS:Our research included 129 AMD patients 131 healthy controls. Genotyping for MCP-1 was performed in 2 groups, genotype allele distributions were checked groups by χ² analysis. Odds ratio (OR) 95% confidence interval (CI) reflected risk. The linkage disequilibrium...

10.12659/msm.921584 article EN Medical Science Monitor 2020-04-02

In this article, the microporous membrane of stretched polytetrafluoroethylene (S-PTFE) film was modified through grafting hydrophilic methacrylic acid (MAA). SEM image showed that grafted poly(methacrylic acid) (PMAA) covered uniquely on regular nanofiber-frame in S-PTFE. The surface contact angle minishes rapidly with increase ratio and falls down to minimum point at 57° when is about 4.7%. water flux PTFE-g-PMAA very sensitive pH values. At lower pH, larger obtained. This contribution...

10.1080/03602559.2018.1455866 article EN Polymer-Plastics Technology and Materials 2018-06-19

Objective To evaluate the effect of intralesional injection triamcinolone acetonide for treatment children chalazion with granulation. Methods This is a retrospective study. sixty-eight cases granulation were treated acetonide.Among cases, 23 hemispherical and 45 granulational obseroed.Surface anesthesia was made 0.4% oxybuprocaine. Triamcinolone 0.05-0.10 ml injected into cyst chalazion. Every patient visited again next week. Results Twenty-three absorbed in 7 days without...

10.3760/cma.j.issn.2095-1477.2016.10.017 article EN Yanwaishang zhiye yanbing zazhi 2016-10-25

Objective To study the effects of indocyanine green (ICG) on rabbit lens epithelial cells(RLECs)proliferation by in vitro culture,and to investigate safety and reliability technology staining capsular with ICG during cataract surgery.Methods RLECs were cultured vitro.The at different concentrations proliferation 24h,48h,72h was measured MTT colorimetric method cell count technique.The morphological changes observed light microscope.Results The result showed that concentration 0.5% 1% can...

10.3760/cma.j.issn.1006-4443.2014.010.028 article EN Chinese Journal of Practical Ophthalmology 2014-10-10

Objective To explore the effect of intravenous infusion team (Ⅳ team) combined with systematic training in safety management peripherally inserted central catheter (PICC).Methods Totals 150 PICC patients before from October 2010 to September 2011 were control group,and after 2012 experimental group.Incidence rate complication and unplanned extubation as well patients' satisfaction compared between two groups training.Results There total 10 cases group,including 2 infection,3 phlebitis,1 case...

10.3760/cma.j.issn.1674-2907.2013.15.032 article EN Zhonghua xiandai huli zazhi 2013-05-26

Abstract Background: Optic disc melanocytoma is a rare tumor of the optic nerve that typically occurs on surface disk. Our purpose was to identify case melanocytoma. Case presentation: A 51-year-old female patient presented with chief complaints black shadows in left eye, having normal visual acuity. Fundus examination eye revealed homogeneous bulging mass located disc. The demonstrated hypofluorescence throughout an angiogram at all stages and had differentiated from malignant melanoma....

10.21203/rs.3.rs-1265811/v1 preprint EN cc-by Research Square (Research Square) 2022-01-20
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