Nikita K. N. Jorritsma

ORCID: 0000-0003-4583-0051
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About
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Research Areas
  • COVID-19 Clinical Research Studies
  • Sepsis Diagnosis and Treatment
  • Dermatological and COVID-19 studies
  • Venous Thromboembolism Diagnosis and Management
  • Long-Term Effects of COVID-19
  • Cerebrovascular and Carotid Artery Diseases
  • Intracranial Aneurysms: Treatment and Complications
  • Streptococcal Infections and Treatments
  • Renal and Vascular Pathologies
  • Lung Cancer Diagnosis and Treatment
  • Pituitary Gland Disorders and Treatments
  • Neonatal and Maternal Infections
  • Esophageal Cancer Research and Treatment
  • Aortic aneurysm repair treatments
  • Gastric Cancer Management and Outcomes
  • Moyamoya disease diagnosis and treatment
  • Vascular Procedures and Complications

University Medical Center Utrecht
2020-2023

Utrecht University
2020-2022

University Hospital Heidelberg
2020

Heidelberg University
2020

Abstract Coronavirus disease 2019 (COVID-19) is a rapidly emerging pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Critical COVID-19 thought to be associated with hyper-inflammatory process that can develop into distress syndrome, critical normally mediated dysfunctional neutrophils. This study tested hypothesis whether neutrophil compartment displays characteristics of hyperinflammation in patients. Therefore, prospective was performed on all patients...

10.1002/jlb.5cova0820-520rrr article EN cc-by Journal of Leukocyte Biology 2020-12-22

Abstract Introduction Bacterial infections are frequently seen in the emergency department (ED), but can be difficult to distinguish from viral and some non-infectious diseases. Common biomarkers such as c-reactive protein (CRP) white blood cell (WBC) counts fail aid differential diagnosis. Neutrophil CD64 (nCD64), an IgG receptor, is suggested more specific for bacterial infections. This study investigated if nCD64 other infectious diseases ED. Methods All COVID-19 suspected patients who...

10.1186/s12873-023-00800-2 article EN cc-by BMC Emergency Medicine 2023-03-14

Abstract Objectives A high incidence of pulmonary embolism (PE) is reported in patients with critical coronavirus disease 2019 (COVID‐19). Neutrophils may contribute to this through a process referred as immunothrombosis. The aim study was investigate the occurrence neutrophil subpopulations blood preceding development COVID‐19 associated PE. Methods We studied admitted ICU our tertiary hospital between 19‐03‐2020 and 17‐05‐2020. Point‐of‐care fully automated flow cytometry performed prior...

10.1111/sji.13023 article EN cc-by-nc Scandinavian Journal of Immunology 2021-01-23

Background: Coronavirus disease of 2019 (COVID-19) is associated with a prothrombotic state and high incidence thrombotic event(s) (TE). Objectives: To study platelet reactivity in hospitalized COVID-19 patients determine possible association the clinical outcomes thrombosis all-cause mortality. Methods: Seventy nine were enrolled this retrospective cohort provided blood samples which response to stimulation ADP TRAP-6 was determined using flow cytometry. Clinical included events, Results:...

10.3389/fmed.2021.650129 article EN cc-by Frontiers in Medicine 2021-04-22

<h3>BACKGROUND AND PURPOSE:</h3> The natural history and optimal treatment of extracranial carotid artery aneurysms are unknown. Gadolinium enhancement the aneurysm wall may reflect inflammation instability. In this study, we investigated feasibility imaging explored a potential relationship with growth presence (silent) brain infarcts white matter lesions. <h3>MATERIALS METHODS:</h3> Fourteen conservatively treated patients 15 asymptomatic underwent gadolinium-enhanced 3T MR at 2 time...

10.3174/ajnr.a6442 article EN cc-by American Journal of Neuroradiology 2020-02-27
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