Dalad Siriwan

ORCID: 0000-0003-4590-8832
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About
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Research Areas
  • Microbial Metabolites in Food Biotechnology
  • Phytochemicals and Antioxidant Activities
  • Cholinesterase and Neurodegenerative Diseases
  • Alzheimer's disease research and treatments
  • Ethnobotanical and Medicinal Plants Studies
  • Chromatography in Natural Products
  • Pineapple and bromelain studies
  • Microencapsulation and Drying Processes
  • Advances in Cucurbitaceae Research
  • Algal biology and biofuel production
  • Medicinal Plants and Neuroprotection
  • Morinda citrifolia extract uses
  • Vitamin C and Antioxidants Research
  • Pharmacological Effects of Medicinal Plants
  • Ziziphus Jujuba Studies and Applications
  • Natural Antidiabetic Agents Studies
  • Biological Research and Disease Studies
  • Phytochemistry and Biological Activities
  • Agricultural pest management studies
  • Agricultural Practices and Plant Genetics
  • Aquaculture Nutrition and Growth
  • Cynara cardunculus studies
  • Phytochemical Studies and Bioactivities
  • Computational Drug Discovery Methods
  • Phytochemistry and biological activity of medicinal plants

Kasetsart University
2018-2024

Mahidol University
2020

Ehime University
2011-2014

Sacred lotus (Nelumbo nucifera) has long been used as a food source and ingredient for traditional herbal remedies. Plant parts contain neuroprotective agents that interact with specific targets to inhibit Alzheimer’s disease (AD). Organic solvents including methanol, ethyl acetate, hexane, n-butanol, are widely employed extraction of sacred but impact safety. Seed embryo, flower stalk, stamen, old leaf, petal, leaf stalk were extracted using hot water (aqueous extraction). The extractions...

10.3390/molecules25163713 article EN cc-by Molecules 2020-08-14

Alzheimer’s disease (AD) is the most common form of dementia, characterized by chronic neuron loss and cognitive problems. Aggregated amyloid beta (Aβ) peptides, a product cleaved precursor protein (APP) beta-secretase 1 (BACE-1), have been indicated for progressive pathogenesis AD. Currently, screening anti-AD compounds in foodstuffs increasing, with promising results. Hence, purpose this study was to investigate extraction conditions, phytochemical contents, properties, targeting Aβ...

10.3390/molecules25081837 article EN cc-by Molecules 2020-04-16

Boesenbergia rotunda (L.) comprises bioactive compounds with biological and pharmacological properties, especially flavonoid osteoblastogenesis-stimulating potential. However, the application of B. in food pharmaceutical industry is restricted by its low solubility stability. Encapsulation becomes an alternative to overcome these restrictions. The purpose study was encapsulate extract freeze-drying investigate effects different wall materials (maltodextrin (MD), gum arabic (GA), their...

10.1016/j.jsps.2024.101998 article EN cc-by-nc-nd Saudi Pharmaceutical Journal 2024-02-20

Sacred lotus (Nelumbo nucifera) is a commercial product in Asian countries. Almost all parts of the plant are consumed as food or used traditional medicine due to their high contents secondary metabolites such phenolics and alkaloids. However, agricultural management sacred occurs during rainy season, enters resting stage dry season. Thus, seasonal variation (beginning, middle end season) was investigated for total phenolic (TPCs), antioxidant capacities inhibitions key enzymes relevant...

10.3390/plants12071441 article EN cc-by Plants 2023-03-24

Thailand is located in the tropics and a wide variety of fruits are grown commercially. However, studies regarding phytonutrients, anti-mutagenic chemopreventive effects these limited. Thus, phytochemical profiles inhibition key enzymes involved obesity diabetes, together with properties eight tropical fruit extracts cultivated Thailand, including Psidium guajava 'Kimju', 'Keenok', Ananas comosus 'Pattavia', 'Phulae', Durio zibethinus 'Chanee', 'Monthong', Carica papaya 'Khaekdum' Mangifera...

10.3390/foods10112600 article EN cc-by Foods 2021-10-27

Cyanobacteria, especially Arthrospira, are valuable resources of nutrients and natural pigments with many beneficial health-related properties. This study optimized the extraction conditions Arthrospira to achieve high phenolic contents antioxidant activities. Under conditions, bioactive compounds (phenolics pigment components), activities, inhibitions key enzymes relevant some non-communicable diseases were compared between platensis maxima. Optimized determined as 2 h shaking time, 50 °C...

10.1038/s41598-024-74492-4 article EN cc-by-nc-nd Scientific Reports 2024-10-11

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. To fight the disease, natural products, including mulberry, with antioxidant activities and inhibitory against key enzymes (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), beta-secretase 1 (BACE-1)) are of interest. However, even in same cultivars, mulberry trees grown different populated locations might possess disparate amounts phytochemical profiles, leading to dissimilar health properties, which cause...

10.3390/molecules25112600 article EN cc-by Molecules 2020-06-03

Alzheimer's disease (AD) is a progressive neurological illness with few effective treatments. Thus, ameliorating the effects of AD using natural products has attracted global attention promising efficacy and safety. In this study, ten tropical fruits including Ananas comosus 'Phulae', 'Pattavia', Carica papaya 'Khaekdum', 'Khaeknuan', Durio zibethinus 'Monthong', 'Chanee', Psidium guajava 'Kimju', 'Keenok', Mangifera indica 'Kaew' 'Namdokmai' were screened for their inhibitory activities...

10.3390/ph15050591 article EN cc-by Pharmaceuticals 2022-05-11

Yacon is a medicinal plant used as traditional medicine by the natives in South America. In Japan, it becomes popular health food. Sesquiterpene Lactones (SLs) from yacon leaves were investigated and active SLs such enhydrin, uvedalin sonchifolin, bearing alpha-methylene-gamma-lactone epoxides functional groups, identified 1H-6000 MHz-NMR. Chemopreventive cytotoxic activities determined using different primary screening methods. this study, all tested strongly inhibited TPA-induced deformed...

10.3923/pjbs.2011.605.609 article EN Pakistan Journal of Biological Sciences 2011-05-01

Traditional remedies using natural ingredients have been handed down over generations, providing collective information for the development of modern therapeutics. These products a long history safe consumption with curative effects but lack scientific-based evidence hinders mass production new containing active particular medicinal properties. This research investigated phenolic profiles and biochemical properties 29 herbal identified in two traditional Thai remedies, Prasachandaeng (PSCD)...

10.1038/s41598-023-49074-5 article EN cc-by Scientific Reports 2023-12-07
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