- Bipolar Disorder and Treatment
- Neurological disorders and treatments
- Electroconvulsive Therapy Studies
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Diet and metabolism studies
- Fetal and Pediatric Neurological Disorders
- COVID-19 and Mental Health
- Advanced Neuroimaging Techniques and Applications
- Treatment of Major Depression
- Healthcare professionals’ stress and burnout
- Biochemical Acid Research Studies
- Electrolyte and hormonal disorders
- Regulation of Appetite and Obesity
- Microscopic Colitis
- Psychoanalysis and Psychopathology Research
- Blood Pressure and Hypertension Studies
- Cardiovascular Syncope and Autonomic Disorders
- Health, Medicine and Society
- Birth, Development, and Health
- Vestibular and auditory disorders
- Eating Disorders and Behaviors
- COVID-19 and healthcare impacts
- Mental Health Treatment and Access
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2016-2022
Hôpital Corentin-Celton
2018-2022
Assistance Publique – Hôpitaux de Paris
2014-2022
Université Paris Cité
2014-2022
CEA Paris-Saclay
2016-2022
Cognitive Neuroimaging Lab
2020-2022
Sorbonne Paris Cité
2014-2020
Délégation Paris 5
2018-2020
Université Paris-Saclay
2013-2020
Inserm
2014-2020
Pioglitazone could induce remission in major depression: a meta-analysis Romain Colle,1,* Delphine de Larminat,1,* Samuel Rotenberg,1 Franz Hozer,1 Patrick Hardy,1 Céline Verstuyft,2 Bruno Fève,3,* Emmanuelle Corruble1,* 1Psychiatry Department, Hôpital Bicêtre, INSERM, UMR S1178, University Paris-Sud, Assistance Publique-Hôpitaux Paris, Le Kremlin France; 2Molecular Genetic, Pharmacogenetics and Hormonology INSERM UMR_S1184, Centre IMVA, 3Endocrinology...
Brain sulcation is an indirect marker of neurodevelopmental processes. Studies the cortical in bipolar disorder have yielded mixed results, probably due to high variability clinical phenotype. We investigated whole-brain a large sample selected patients with load.A total 263 I and 320 controls were included multicentric magnetic resonance imaging (MRI) study. All subjects underwent high-resolution T1-weighted brain MRI. Images processed automatized pipeline extract global sulcal index (g-SI)...
BackgroundLithium (Li) is a first-line treatment for bipolar disorder (BD). To study its cerebral distribution and association with plasma concentrations, we used 7Li magnetic resonance imaging at 7T in euthymic patients BD treated Li carbonate least 2 years.MethodsThree-dimensional scans (N = 21) were acquired an ultra-short echo-time sequence using non-Cartesian k-space sampling scheme. Lithium concentrations ([Li]) estimated phantom replacement approach accounting differential T1 T2...
The cerebellum is involved in cognitive processing and emotion control. Cerebellar alterations could explain symptoms of schizophrenia spectrum disorder (SZ) bipolar (BD). In addition, literature suggests that lithium might influence cerebellar anatomy. Our aim was to study anatomy SZ BD, investigate the effect lithium.Participants from 7 centers worldwide underwent a 3T MRI. We included 182 patients with SZ, 144 322 controls. automatically segmented using CERES pipeline. All outputs were...
Lithium (Li) is the gold standard treatment for bipolar disorder (BD). However, its mechanisms of action remain unknown but include neurotrophic effects. We here investigated influence Li on cortical and local grey matter (GM) volumes in a large international sample patients with BD healthy controls (HC).We analyzed high-resolution T1-weighted structural magnetic resonance imaging scans 271 type I (120 undergoing Li) 316 HC. Cortical GM were compared using voxel-wise approaches voxel-based...
Objectives Despite evidence of low representativeness clinical trial results for depression in adults, the generalizability late-life is unknown. This study sought to quantify pharmacologic and psychotherapy unipolar depression.Method Data were derived from 2004–2005 National Epidemiologic Survey on Alcohol Related Conditions (NESARC), a nationally representative sample 34,653 adults United States population. To assess depression, we applied standard set eligibility criteria trials all...
Depression is a severe and heterogeneous disorder resulting from interacting genetic, environmental, epigenetic factors. Nutrient deficiency bariatric bypass surgery has been involved in the pathophysiological mechanisms of depression treatment response. We report case patient who developed, after surgery, depressive episode, refractory to both pharmacological electroconvulsivotherapy (ECT). Folate was evidenced. A dramatic response ECT observed folate supplementation. focused on involvement...
To the Editor: Major depressive disorder is a heterogenous disease considered as cluster of symptoms associated with disordered processing within specific neurobiological circuits. We report case patient suffering from melancholic depression Capgras’ and Cotard’s delusions in which clinical picture was particular pattern cerebral activity. Case report. Mr A 72-year-old man, who brought to emergency service complaints insomnia, nonsense talk, aggressive behavior. For 2 weeks, had lived...
Panic disorder in the elderly is an understudied disorder, despite being associated with substantial functional impairment, a diminished quality of life and increased suicide risk this population. This likely to be underdiagnosed sometimes inadequately treated due absence national international guidelines for vulnerable Few therapeutic trials have specifically focused on efficacy tolerability pharmacological psychotherapy treatments panic current approaches detect manage are mainly based...