A5025048408- Diet and metabolism studies
- RNA Research and Splicing
- RNA modifications and cancer
- Molecular Biology Techniques and Applications
- Diet, Metabolism, and Disease
- RNA and protein synthesis mechanisms
- Eating Disorders and Behaviors
- Obesity, Physical Activity, Diet
- Bariatric Surgery and Outcomes
- Muscle metabolism and nutrition
- Nutritional Studies and Diet
- Adipose Tissue and Metabolism
- Diabetes Management and Education
- Ovarian function and disorders
- Health and Lifestyle Studies
- Growth Hormone and Insulin-like Growth Factors
- Liver Disease Diagnosis and Treatment
University of Michigan
2019-2025
Berkeley College
2024
University of California, Berkeley
2010-2018
Walter and Eliza Hall Institute of Medical Research
2010
Lawrence Berkeley National Laboratory
2010
University of California, San Francisco
2010
Background: Type 2 diabetes is a prevalent, chronic disease for which diet an integral aspect of treatment. In our previous trial, we found that recommendations to follow very low-carbohydrate ketogenic and change lifestyle factors (physical activity, sleep, positive affect, mindfulness) helped overweight people with type or prediabetes improve glycemic control lose weight. This was in-person intervention, could be barrier without the time, flexibility, transportation, social support, and/or...
Abstract Background Insulin resistance and the G allele of rs738409 interact to create a greater risk metabolic dysfunction–associated steatotic liver disease. Objective This study aims confirm that one promising way reduce insulin is by following very low–carbohydrate (VLC) dietary pattern. Methods Adults with rs738409-GG or -CG steatosis elevated function tests, were taught an ad libitum VLC diet, positive affect mindful eating skills, goal setting, self-monitoring given feedback coaching...
Protein isoforms produced by alternative splicing (AS) of many genes have been implicated in several aspects cancer genesis and progression. These observations motivated a genome-wide assessment AS breast cancer. We accomplished this measuring exon level expression 31 nonmalignant immortalized cell lines representing luminal, basal, claudin-low subtypes using Affymetrix Human Junction Arrays. analyzed these data computational pipeline specifically designed to detect with low false-positive...
<h3>PURPOSE</h3> Adults with a triple multimorbidity (hypertension, prediabetes or type 2 diabetes, and overweight obesity), are at increased risk of serious health complications, but experts disagree on which dietary patterns support strategies should be recommended. <h3>METHODS</h3> We randomized 94 adults from southeast Michigan this using × diet-by-support factorial design, comparing very low-carbohydrate (VLC) diet vs Dietary Approaches to Stop Hypertension (DASH) diet, as well results...
Background Adults with type 2 diabetes may experience health benefits, including glycemic control and weight loss, from following a very low–carbohydrate, ketogenic (VLC) diet. However, it is unclear which ancillary strategies enhance these effects. Objective This pilot study aims to estimate the effect sizes of 3 intervention enhancement (text messages, gifts, breath vs urine ketone self-monitoring) that improve outcomes 12-month web-based ad libitum VLC diet lifestyle for adults diabetes....
Background A very low–carbohydrate (VLC) nutritional strategy may improve glycemic control and weight loss in adults with type 2 diabetes (T2D). However, the supplementary behavioral strategies that might be able to outcomes using this are uncertain. Objective This study aims compare impact of adding 3 different a web-based VLC diet intervention. To our knowledge, is first trial randomize participants frequencies dietary self-monitoring. Methods The included 112 overweight T2D (hemoglobin...
To study the impact of a very-low-carbohydrate (VLC) diet for 16 weeks in overweight or obese women with polycystic ovary syndrome (PCOS).Single-arm prospective pilot study.We recruited participants using medical records from an academic center.Twenty-nine (body mass index, 25-50 kg/m2) PCOS.We taught to follow VLC and provided information about variety behavioral skills including mindfulness positive affect online 16-week intervention.Changes body weight, glycated hemoglobin, PCOS-related...
Abstract Background Approximately one-third of US young adults (18–25 years) have obesity, and there are calls to help lose weight prevent weight-related chronic conditions. This pilot trial tested the feasibility acceptability a very low-carbohydrate (VLC) eating pattern, with supportive positive affect mindful skills, for management among females obesity. Methods In single-arm trial, women ( N = 17), aged 19–23, obesity participated in 4-month diet lifestyle intervention. Participants were...
<p>Supplementary Figures S1-S2 and Supplementary Tables S2-S4.</p>
<p>Supplementary Figures S1-S2 and Supplementary Tables S2-S4.</p>
<div>Abstract<p>Protein isoforms produced by alternative splicing (AS) of many genes have been implicated in several aspects cancer genesis and progression. These observations motivated a genome-wide assessment AS breast cancer. We accomplished this measuring exon level expression 31 nonmalignant immortalized cell lines representing luminal, basal, claudin-low subtypes using Affymetrix Human Junction Arrays. analyzed these data computational pipeline specifically designed to...
<div>Abstract<p>Protein isoforms produced by alternative splicing (AS) of many genes have been implicated in several aspects cancer genesis and progression. These observations motivated a genome-wide assessment AS breast cancer. We accomplished this measuring exon level expression 31 nonmalignant immortalized cell lines representing luminal, basal, claudin-low subtypes using Affymetrix Human Junction Arrays. analyzed these data computational pipeline specifically designed to...
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<sec> <title>BACKGROUND</title> Adults with type 2 diabetes may experience health benefits, including glycemic control and weight loss, from following a very low–carbohydrate, ketogenic (VLC) diet. However, it is unclear which ancillary strategies enhance these effects. </sec> <title>OBJECTIVE</title> This pilot study aims to estimate the effect sizes of 3 intervention enhancement (text messages, gifts, breath vs urine ketone self-monitoring) that improve outcomes 12-month web-based...