BACKGROUND: Osteoarthritis of the knee (KOA) is main cause disability in elderly people. Patients with KOA may often not achieve adequate pain control even after receiving all treatment modalities. OBJECTIVES: The objective this study was to examine efficacy ultrasound-guided radiofrequency ablation (RFA) as a for moderate and severe KOA. STUDY DESIGN: A prospective randomized controlled study. SETTING: performed National Pain Management Research Center China-Japan Friendship Hospital....

What is known and Objective: Bone-cancer pain a common refractory cancer pain. Opioids, on their own, do not control this type of well enough, co-analgesics are necessary. Methods: Patients with bone metastasis-related at Numeric Rating Scale ≥4 were enrolled to randomized placebo-controlled trial. They had also received morphine or transdermal fentanyl patches for least 1 week. During the 3-day efficacy phase, patients placebo 1–3 tablets oxycodone/paracetamol (5/325 mg), four times daily 3...

Objective . To explore the efficacy of electroacupuncture treatment in cancer induced bone pain (CIBP) rat model with morphine tolerance and changes calcitonin‐gene related peptide (CGRP) expression dorsal root ganglion (DRG). Methods Forty SD rats were divided into five groups: sham, CIBP (B), + (BM), (BE), (BME). B, BM, BE, BME groups prepared model. The latter three then accepted morphine, electroacupuncture, combined separately, nine days consecutively (M1 to M9). Mechanical withdraw...

9534 Background: Bone metastatic lung cancer or breast pts often have neuropathic pain which has poor reaction to opioids. A clinical trial is investigate efficacy of electroacupuncture (EA) in with pain. Methods: Inclusion criteria were: bone at least one the symptoms as burning pain, shooting dysesthesias, allodynia; numerical rating scale (NRS) intensity >=4.0; stable dose opioids for 72 hours. Exclusion chemotherapy radiotherapy from 15 days before during study. Hormone adjuvant...

e19691 Background: Pain relief is often unsatisfied in metastatic bone pain despite the availability of strong opioids, and some pts can not bear severe opioids side effects. Our trial to determine whether adding oxycodone 5 mg/acetaminophen 325 mg combination tablet on time could improve already receiving opioids. Methods: Inclusion criteria were: Bone cancer with definite iconography diagnosis; NRS (0 no pain, 10 worst pain) intensity ≥4; stable dose for at least 72 hours; KPF score≥50....

Objective To explore the efficacy of electroacupuncture treatment in cancer induced bone pain (CIBP)-morphine tolerance rat model and expression calcitonin-gene related peptide(CGRP) immunohistochemisty dorsal root ganglion (DRG). Methods Forty SD rats were divided into four groups: sham group, CIBP+ morphine group(BM), group (BE), tolerance+ (BME). BM, BE BME groups prepared CIBP by carcinoma cell tibia implanted.After six days, three accepted morphine, electroacupuncture, combined...

Objective To investigate the efficacies and differences of spinal cord stimulation (SCS) pulsed radiofrequency (PRF) in treatment herpes zoster neuralgia elderly. Methods Sixty-three patients with over 50 years old, admitted to our hospital from January 2018 2019, were divided into SCS group (n=31) PRF (n=32) by prospective, randomized controlled study. The stimulating electrodes placed epidural ganglion segment for two weeks after percutaneous puncture group. In group, needles...

Background: Postherpetic neuralgia (PHN) occurs in 9% to 34% of herpes zoster (HZ) patients, and the incidence PHN is positively correlated with age. A number patients suffer from poor therapeutic effects or intolerable side need accept minimally invasive analgesia. Objectives: This study aimed investigate spinal cord stimulation (SCS) pulsed radiofrequency (PRF) on treatment elderly HZ-related pain persisting beyond acute phase. Study Design: prospective, randomized-controlled trial....