- Glioma Diagnosis and Treatment
- Neuroblastoma Research and Treatments
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
- Neurofibromatosis and Schwannoma Cases
- Cancer, Hypoxia, and Metabolism
- Spinal Dysraphism and Malformations
- Ophthalmology and Eye Disorders
- Vestibular and auditory disorders
- Facial Trauma and Fracture Management
- Sarcoma Diagnosis and Treatment
- DNA Repair Mechanisms
- Cancer-related molecular mechanisms research
- Amoebic Infections and Treatments
- Advanced Neuroimaging Techniques and Applications
- Developmental Biology and Gene Regulation
- Cell Adhesion Molecules Research
- Epilepsy research and treatment
- Hereditary Neurological Disorders
- melanin and skin pigmentation
- Management of metastatic bone disease
- Brain Metastases and Treatment
- Histone Deacetylase Inhibitors Research
- Cleft Lip and Palate Research
Meyer Children's Hospital
2007-2019
Neurology, Inc
2009-2010
Boston Children's Hospital
2009
Meyer Children's Hospital
2008
Hôpital des Enfants
2005-2006
The resorbable plating system allows the infant's skull to grow once is resorbed, thus not inhibiting necessary developmental growth seen with titanium system. Despite marked improvements in long-term outcomes, there are still technical points that can be followed maximize outcome while reducing and possibly eliminating minor complications such as plate palpability visibility through skin well breakdown over plate. A retrospective electronic chart review was performed on pediatric patient...
Embryonal tumors are a group of malignant neoplasms that most commonly affect the pediatric population. tumor with abundant neuropil and true rosettes is recently recognized rare tumor. It composed neurocytes undifferentiated neuroepithelial cells arranged in clusters, cords several types prominent neuropil-rich background. We describe new case this The patient, 24-month-old female infant, was referred to Meyer Children's Hospital history right brachio-crural deficit associated occasional...
Ependymomas are the third most common brain tumor in children. The post surgical management is controversial. There no convincing data on an effective role for chemotherapy. O(6)-Methylguanine-DNA-Methyltransferase (MGMT) a DNA repair protein considered to be chemosensitivity predictor. Hypermethylation of MGMT gene promoter important cause inactivation. We evaluated methylation and immunohistochemical expression 12 recurrent anaplastic ependymomas affecting Our purpose was investigate...
Rhabdoid meningioma is an uncommon variant categorized as WHO grade III. The majority of cases occur in adulthood. Herein, we describe a right fronto-temporal rhabdoid affecting 3-year-old boy. lesion measured approximately 4 cm diameter and incorporated the ipsilateral middle cerebral artery. Sub-total surgical excision mass was performed. Histologically, tumor mainly composed globoid plump cells with inclusion-like eosinophilic cytoplasm, peripheral nuclei, prominent nucleoli occasional...
Abstract Von Hippel–Lindau (VHL) disease is a cancer‐prone syndrome characterized by abnormalities in vascular proliferation and the development of both visceral CNS tumors. Complications from hemangioblastoma are among principal causes death this syndrome. Antiangiogenic therapy has been used with different modalities patients suffering such complications. Here, we describe an adolescent VHL complicated progressive, multifocal spinal hemangioblastomas. Treatment single‐agent thalidomide...
Pilomyxoid astrocytoma is a recently described tumor. Its most typical morphological characteristics are an angiocentric astrocytic proliferation embedded in myxoid background. The behavior seems to be unfavorable due the reported high rate of local recurrence. earlier studies indicated that pilomyxoid typically affects young children and arises hypothalamic/chiasmatic region. We report case 14-year-old patient with 6-year history absence seizure. Magnetic resonance imaging showed right...
Glioneuronal tumors with neuropil-like islands are rare. The 1st reported cases were localized in the cerebral hemispheres of adults, showed homogeneous histopathologic features (infiltrating astrocytic growth and rimmed by neuronal cells), had an unfavorable behavior. We report 3 pediatric (1 boy 2 girls, ages 4, 6, 8 years, respectively). a tumor, girls spinal tumor. younger girl also multiple posterior fossa lesions. older underwent gross total resection. subtotal resection tumor; lesions...
The authors report a case study of giant cyst the cavum septi pellucidi, Vergae and veli interpositi spreading to posterior fossa, initially treated elsewhere by ventriculoperitoneal shunt, with no resolution symptomatology. A few months later patient was successfully fenestration into ventricular system through neuroendoscopic technique, at Pediatric Neurosurgical Center Meyer Children's Hospital in Florence. Symptomatic midline cysts are quite rare different techniques have been proposed...