A5031981504- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Nerve Injury and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Spinal Dysraphism and Malformations
- Stroke Rehabilitation and Recovery
- Cerebrospinal fluid and hydrocephalus
- Craniofacial Disorders and Treatments
- Spinal Cord Injury Research
- Neonatal and fetal brain pathology
- Intraoperative Neuromonitoring and Anesthetic Effects
- Ophthalmology and Eye Disorders
- Neonatal Health and Biochemistry
- Parvovirus B19 Infection Studies
- Teratomas and Epidermoid Cysts
- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Acute Ischemic Stroke Management
- Scoliosis diagnosis and treatment
- Tumors and Oncological Cases
- Cardiac Imaging and Diagnostics
- Traumatic Brain Injury and Neurovascular Disturbances
- Myofascial pain diagnosis and treatment
- Congenital gastrointestinal and neural anomalies
- Neurogenetic and Muscular Disorders Research
Shanghai Children's Hospital
2016-2024
Shanghai Jiao Tong University
2016-2024
Abstract Purpose Our aim was to test whether the newly modified rhizotomy protocol which could be effectively used guide single-level approach selective dorsal (SL-SDR) treat spastic hemiplegic cases by mainly releasing those muscles (target muscles) marked pre-operatively in their lower limbs still applicable quadriplegic or diplegic cerebral palsy (CP) pediatric population. Methods In current study, we retrospectively conducted a cohort review of younger than 14 years age diagnosed with CP...
Abstract Background Functional role of filum terminale (FT) was not well studied though it contains structure basis for nerve impulse conduction. We aimed to explore the possible functions FT from perspective triggered electromyography (EMG) during surgery. Methods retrospectively reviewed intraoperative neurophysiological monitoring data pediatric patients who underwent intradural surgeries at lumbar level in Shanghai Children’s. Hospital January 2018 March 2023. Altogether 168 cases with...
Objective This study aimed to investigate the electro-neurophysiological characteristics of ventral and dorsal nerves at L2 segment in a quantitative manner. Methods Medical records consecutive patients who underwent single-level approach selective rhizotomy (SDR) from June 2019 January 2022 were retrospectively reviewed. Intraoperative data analyzed. Results A total 74 males 27 females included current with mean age 6.2 years old. Quadriceps adductors two main muscle groups innervated by...
Abstract Selective dorsal rhizotomy (SDR) can reduce the spasticity in patients with spastic cerebral palsy (SCP) and thus improve motor function these patients, but different levels of improvement were observed among after SDR. The aim present study was to subgroup predict possible outcome SDR based on pre-operational parameters. A hundred thirty-five pediatric diagnosed SCP who underwent from January 2015 2021 retrospectively reviewed. Spasticity lower limbs, number target muscles,...
Cortical visual impairment (CVI) is the common cause of pediatric in cerebral palsy (CP) while exotropia most strabismus associated with CP. We aim to observe strabismic surgery outcomes patients CP and CVI.Our medical records were collected from treated our hospital May 1, 2017 Jan 2022. With normal intelligence assessment diagnosis children CVI, microsurgeries performed under intravenous combined inhalation anesthesia. The was examined by prism test best vision correction contrast...
Background: Spastic cerebral palsy (CP) is a prevalent cause of motor dysfunction in children, with patients often experiencing secondary musculoskeletal deformities, including tibial torsion. This study aimed to investigate the short-term effect selective dorsal rhizotomy (SDR) on torsion children spastic CP. Methods: We conducted retrospective review CP who underwent SDR at Department Neurosurgery, Shanghai Children’s Hospital, between July 2019 and November 2022. Pre- post-operative...
Selective dorsal rhizotomy (SDR) can decrease spasticity in children suffering from spastic cerebral palsy (SCP) and thus improve their moving ability when supplemented with the post-operational rehabilitation program. In this case, study aims to investigate gait changes mild SCP after SDR short-term follow-up. The information of ambulatory cases who underwent our center was retrospectively reviewed, comparisons spasticity, motor function data analysis before were analyzed. total, 32...
Abstract Objective To explore the clinical features, diagnosis, treatment and prognosis of Langerhans cell histiocytosis (LCH) skull in children. Methods This study retrospectively summarized manifestations, methods follow-up status children with LCH who were admitted to Department Neurosurgery Shanghai Children’s Hospital from January 2014 June 2021. Results A total 23 patients confirmed by histology as received hospitalization treatment, including 14 males 9 females, aged (5.76 ± 3.86)...
BACKGROUND AND OBJECTIVES: Selective dorsal rhizotomy (SDR) reduces spasticity in children with spastic cerebral palsy (CP). Intraoperative neurophysiology, triggered electromyography (trigger-EMG) is crucial guiding sensory rootlet selection, but its reproducibility during SDR surgery has not been fully investigated. The objective of this study was to evaluate the trigger-EMG performed CP. METHODS: A retrospective review for cases where roots were stimulated twice 1 2 minutes apart using a...
To investigate the urodynamic study (UDS) result in pediatric patients suffering from spastic cerebral palsy (CP). Medical records of diagnosed CP having pre-operative UDS results underwent selective dorsal rhizotomy (SDR) Jan. 2020 to May. 2021 were retrospectively reviewed. Fifty-seven cases included (mean age, 6.73 ± 2.84 years), among which, 46 ambulatory and 11 non-ambulatory. Average gross motor function measure-66 (GMFM-66) score was 62.16 11.39. Reduced bladder capacity seen 49.12%...
For decades, intraoperative neurophysiological monitoring (IONM) has been used to guide selective dorsal rhizotomy (SDR) for the treatment of spastic cerebral palsy (CP). Electromyography (EMG) interpretation methods, which are core IONM, have never fully discussed and addressed, their importance necessity in SDR questioned years. However, outcomes CP patients who undergone IONM-guided favorable, surgery-related complications extremely minimal. In this paper, we review history evolving EMG...
Objective To explore the effects of oral administration glucose solution for pain relief during screening retinopathy prematurity(ROP) in preterm infants. Methods The study was conducted neonatal intensive care units(NICU) Children′s Hospital Shanghai from 1 August 2014 to 31 July 2015. A total 95 infants who need ROP enrolled current study, were randomly divided into experimental group(n=45) and control group(n=50) accordance with random number table. The group continuing given 25%...
Objective To evaluate the effectiveness of single-level laminectomy selective dorsal rhizotomy(SL-SDR) plus intensive rehabilitation for children with spastic cerebral palsy. Methods For evaluating changes motor function, clinical data were reviewed 21 cases palsy. SL-SDR was followed by at least 6 months from November 2015 to August 2016. Objective muscular tone, joint range movement(ROM), strength and gross function classification system(GMFCS) level preoperatively, 3...
Abstract Purpose: Some newborns' cephalhematoma will ossify if it lasts for a long time, which affect the shape of head and lead to other complications. There is still controversy about operation. Our purpose evaluate whether operation can effectively improve skull clinicians' understanding ossification cephalhematoma. Methods: A retrospective cohort review in ossified cases who had undergone ablation Department Neurosurgery Shanghai Children’s Hospital, School medicine, Jiao Tong University...
Objective To evaluate the efficacy of novel protocol guided single-level laminectomy selective dorsal rhizotomy (SL-SDR) plus intensive rehabilitation for children with spastic cerebral palsy and explore relevant prognostic factors. Methods A retrospective analysis was conducted clinical data 67 undergoing SL-SDR from September 2015 to October 2016. Analysis muscular tone, joint range movement, strength, gross motor function classification system(GMFCS) grading measure-66(GMFM-66)...
Abstract Background Selective Dorsal Rhizotomy (SDR) guided by our modified protocol can decrease spasticity in certain muscles. This study aimed to investigate gait parameters changes cerebral palsy (CP) with focal after SDR short-term follow-up. Methods CP classified as Gross Motor Function Classification System (GMFCS) level Ⅰ and Ⅱ who underwent were included. Changes of spasticity, deviation index (GDI) retrospectively reviewed. Results contained 26 individuals 44 affected 8 intact...
Abstract Objective To investigate the urodynamic study (UDS) result in pediatric patients with spastic cerebral palsy (CP). Material and methods Medical records of CP pre-operative UDS results underwent selective dorsal rhizotomy (SDR) from Jan. 2020 to May. 2021 were retrospectively reviewed. Results Fifty-seven cases included study. Among these cases, 46 ambulatory 11 non-ambulatory. Average gross motor function measure - 66 (GMFM 66) score was 62.16 ± 11.39. Reduced bladder capacity seen...