A5008316244- Vector-borne infectious diseases
- Insect and Pesticide Research
- Vector-Borne Animal Diseases
- Toxin Mechanisms and Immunotoxins
- Insect Resistance and Genetics
- Viral Infections and Vectors
- Insect symbiosis and bacterial influences
- Mosquito-borne diseases and control
- Research on Leishmaniasis Studies
- Aquaculture Nutrition and Growth
- Neurobiology and Insect Physiology Research
- Entomopathogenic Microorganisms in Pest Control
- Parasites and Host Interactions
- Plant Parasitism and Resistance
- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Studies on Chitinases and Chitosanases
- Calpain Protease Function and Regulation
- Trypanosoma species research and implications
- Insect Pest Control Strategies
- Animal Genetics and Reproduction
- Study of Mite Species
- Insect and Arachnid Ecology and Behavior
- Heat shock proteins research
- Microbial Inactivation Methods
Universidade Federal do Rio Grande do Sul
2016-2025
National University of Singapore
2024
National Institute of Allergy and Infectious Diseases
2024
Abdul Wali Khan University Mardan
2024
Universidade Federal do Rio de Janeiro
2024
Instituto Nacional de Ciência e Tecnologia em Entomologia Molecular
2024
Universidade Federal do Rio Grande
2023
Hokkaido University
2017
Abstract The cattle tick Rhipicephalus microplus is a hematophagous ectoparasite that causes important economic losses in livestock. Different species of ticks harbor symbiont bacterium the genus Coxiella . It was showed endosymbiont from R (CERM) vertically transmitted mutualist symbiont, comprising 98% 16S rRNA sequences both eggs and larvae. Sequencing bacterial genome revealed genes for biosynthetic pathways several vitamins key metabolic cofactors may provide nutritional complement to...
The tick Rhipicephalus (Boophilus) microplus is a blood-sucking ectoparasite of cattle that severely impairs livestock production. Studies on immunological control address mostly single-antigen vaccines. However, from the commercial standpoint, so far no vaccine has afforded appropriate protection against all R. populations. In this context, multi-antigen cocktails have emerged as way to enhance efficacy. work, multi-antigenic was analyzed under field conditions in naturally infested cattle....
Recombinant Glutathione S-transferase of Haemaphysalis longicornis (rGST-Hl) was expressed in Escherichia coli, purified by affinity chromatography and used the immunization cattle. Western blot analysis showed positive antibody response cattle immunized with rGST-Hl. The tests also that bovine sera recognize native Rhipicephalus microplus proteins different tissue extracts. Furthermore, vaccine potential rGST-Hl investigated against infestation Hereford R. microplus. Vaccination conferred...
Ticks have serious impacts on animal and human health, causing significant economic losses in cattle breeding. Besides damage due to the hematophagous behavior, they transmit several pathogens. Low cost environmental safety made vaccines a promising alternative control method against tick infestation. Metalloproteases (MPs) been shown be essential for diverse biological functions organisms, inhibiting blood clotting, degrading extracellular matrix proteins, host tissue repair via...
Abstract Background Tick control is mostly hampered by the rise of acaricide-resistant tick populations. Significant efforts have focused on developing alternative methods, including cross-species protective and/or cocktail-based anti-tick vaccines, to achieve protection against various species. Methods In this study, full-length open reading frames encoding subolesin (SUB) from Rhipicephalus microplus and ferritin 2 (FER2) Hyalomma anatolicum as well partial 60S acidic ribosomal protein...
The tick Rhipicephalus (Boophilus) microplus (formerly Boophilus microplus) is the major ectoparasite affecting livestock in America, Asia, Africa, and Oceania.Conventional control based on use of acaricides but immunization bovines with gut proteins induces only a partial protective immune response.Based this information, distinct research groups have explored possibility protecting animals by inducing an response against other proteins.However, antigens so far described do not induce...
The advancement of multi-omics technologies is crucial to deepen knowledge on tick biology. These approaches, used study diverse phenomena, are applied experiments that aim understand changes in gene transcription, protein function, cellular processes, and prediction systems at global biological levels. This review addressed the application omics data investigate elucidate physiological such as feeding, digestion, reproduction, neuronal, endocrine systems, understanding population dynamics,...
The ticks Rhipicephalus appendiculatus and sanguineus are the main vectors of Theileria parva Babesia spp. in cattle dogs, respectively. Due to their impact veterinary care industry, improved methods against R. parasitism under development, including vaccines. We have previously demonstrated induction a cross-protective humoral response microplus following vaccination with recombinant glutathione S-transferase from Haemaphysalis longicornis tick (rGST-Hl), suggesting that this protein could...
Cocktail vaccines are proposed as an attractive way to increase protection efficacy against specific tick species. Furthermore, such made with different antigens have the potential of cross-protecting a broad range However, there still limitations selection immunogen candidates. Acknowledging that glutathione S-transferases (GSTs) been exploited ticks and other parasites, this study aimed analyze GST-cocktail vaccine broad-spectrum vaccine. To constitute vaccine, five species economic...
In the past decade, metagenomics studies exploring tick microbiota have revealed widespread interactions between bacteria and arthropods, including symbiotic interactions. Functional showed that obligate endosymbionts contribute to biology, affecting reproductive fitness molting. Understanding molecular basis of interaction ticks their mutualist may help develop control methods based on microbiome manipulation. Previously, we Rhipicephalus microplus larvae with reduced levels Coxiella...
ABSTRACT: Rhipicephalus ( Boophilus) species are monoxenous ticks with seasonal distribution in tropical and subtropical regions. For many years, micropluswas considered as a single species; however, further analysis split these into two distinct species. Because R. microplusand australisshare similar attributes, it is hard to discriminate explain the changes classification of parasites over past decades. The reappearance australisis an outcome new research, which has afforded better...
Cystatins are a group of cysteine protease inhibitors responsible for physiological proteolysis regulation and present in wide range organisms. Studies about this class parasites have contributed to clarify their roles important processes, like blood digestion modulation host immune response during feeding. Thus, cystatins subject research on the development new parasite control methods. Additionally, characterization proteins shared by different species represents valuable strategy find...
The ticks Rhipicephalus (Boophilus) microplus and Haemaphysalis longicornis are blood-sucking ectoparasites of bovines, causing serious damages to the livestock production. main control method for these is based on acaricides. However, use vaccines has been studied as a promising strategy. Calreticulin (CRT) multifunctional, predominantly intracellular protein present in almost all cells animals. secretion CRT during feeding might be linked modulation parasite–host interaction. In study,...
Tick embryogenesis is a metabolically intensive process developed under tightly controlled conditions and whose components are poorly understood.In order to characterize the role of AKT (protein kinase B) in glycogen metabolism cell viability, determination, identification cloning an from Rhipicephalus microplus were carried out, parallel with experiments using RNA interference (RNAi) chemical inhibition.A decrease content was observed when chemically inhibited by 10-DEBC treatment, while...