A5023449373- Inflammatory Bowel Disease
- Microscopic Colitis
- Appendicitis Diagnosis and Management
- Liver Disease Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Intraperitoneal and Appendiceal Malignancies
- Gastric Cancer Management and Outcomes
- Helicobacter pylori-related gastroenterology studies
- Immunodeficiency and Autoimmune Disorders
- Hepatitis B Virus Studies
- Healthcare Policy and Management
- Eosinophilic Esophagitis
- Diverticular Disease and Complications
- Diagnosis and treatment of tuberculosis
- Hepatitis C virus research
- Mycobacterium research and diagnosis
- Liver Disease and Transplantation
St Vincent's Hospital
2017-2024
The University of Melbourne
2017-2024
Monash Health
2022
Transmural healing is emerging as a key treatment target in Crohn's disease. This study aimed to determine the role of magnetic resonance imaging (MRI) and intestinal ultrasound (IUS) assessment radiologic response disease strictures treatment. The STRIDENT (Stricture Definition Treatment) was randomized controlled trial (2:1) intensive high-dose adalimumab combined with thiopurine vs standard dose monotherapy patients stricturing Clinical defined reduction Obstructive Symptom Score at 12...
To evaluate the long-term treatment outcomes of tenofovir therapy in patients a real world Australian tertiary care setting.We performed retrospective analysis among treatment-naïve and treatment-experienced receiving minimum 3 mo through St Vincent's Hospital Melbourne, Australia. We included [tenofovir disoproxil fumarate (TDF)] monotherapy, as well treated with TDF combination second antiviral agent. Patients were excluded if they demonstrated human immune-deficiency virus/hepatitis C...
The economic burden of decompensated chronic liver disease (CLD) on Australian healthcare services is poorly characterised.To evaluate the in-patient utilisation costs associated with CLD at Monash Health, an tertiary service.The current retrospective cost analysis examined patients admitted between 1 January 2012 and 31 December 2018. Hospitalisations were identified using CLD-specific International Classification Diseases, Tenth Revision, codes. Cost measures estimated Victorian Weighted...
Abstract Background The randomised STRIDENT (Stricture Definition and Treatment) trial showed that Crohn’s disease symptomatic strictures are responsive to anti-TNF therapy with most patients clinically improved after 12 months treatment adalimumab +/- thiopurine. Treat target intensification resulted in greater stricture morphology improvement. We present here 2 year (from study entry) follow up assess response durability risk of surgery. Methods Patients associated inflammation (elevated...
Abstract Background Mucosal and transmural healing are associated with better outcomes in Crohn’s disease. Magnetic resonance imaging (MRI) intestinal ultrasound (IUS) provide non-invasive cross-sectional assessment of disease activity healing. This systematic review addresses the utility MRI IUS response to drug therapy when compared endoscopy patients luminal Methods Database searches were undertaken (Medline, Embase, Emcare, APA PsycInfo, CINAHL, Cochrane Library) following PRISMA...
Abstract Background Transmural healing is a treatment goal in the management of Crohn’s disease, and intestinal ultrasound (IUS) potentially sensitive, non-invasive reproducible means to assess response treatment. Methods The STRIDENT (Stricture Definition Treatment) study was randomised controlled trial standard dose monotherapy adalimumab versus intensive high-dose combined with thiopurine. disease patients symptomatic strictures were 2:1 high induction (160mg weekly for 4 weeks) 40mg...