A5040162149- Osteoarthritis Treatment and Mechanisms
- Nerve injury and regeneration
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
- Mesenchymal stem cell research
- Bone and Joint Diseases
- Knee injuries and reconstruction techniques
- Bone Tissue Engineering Materials
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Tendon Structure and Treatment
- 3D Printing in Biomedical Research
- Bone health and treatments
- Bone fractures and treatments
- Silk-based biomaterials and applications
- Neurogenesis and neuroplasticity mechanisms
- Gut microbiota and health
- Orthopedic Infections and Treatments
- Neuroscience and Neural Engineering
- Total Knee Arthroplasty Outcomes
- Dental Implant Techniques and Outcomes
- Bone Metabolism and Diseases
- Nerve Injury and Rehabilitation
- Ferroptosis and cancer prognosis
Chinese PLA General Hospital
2016-2025
Dalian Medical University
2025
Chongqing Medical University
2025
Second Affiliated Hospital of Chongqing Medical University
2025
Liaoning Cancer Hospital & Institute
2018-2025
China Medical University
2018-2025
Yanbian University
2025
Shandong University
2017-2024
Nantong University
2017-2024
Wuxi No.2 People's Hospital
2020-2024
A biodegradable and self-electrified conduit device is achieved to offer postoperative electrical cues for nerve regeneration.
/Objective: The treatment of bone defect has always been a difficult problem in orthopedic clinic. search for alternative biodegradable implants is hot topic. development magnesium scaffolds the defects long goal public.In this study, we proposed porous scaffold prepared by 3D gel printing and surface modification with an additional calcium phosphate coating use its strength, degradability slow degradation rate graft substitute material. granular was technology modified DCPD (Dibasic Calcium...
Given the advantages of high energy density and easy deployment, biodegradable primary battery systems remain as a promising power source to achieve bioresorbable electronic medicine, eliminating secondary surgeries for device retrieval. However, currently available biobatteries are constrained by operational lifetime, biocompatibility, biodegradability, limiting potential therapeutic outcomes temporary implants. Herein, we propose fully zinc–molybdenum (Zn–Mo) with prolonged functional...
We have previously reported a natural, human cartilage ECM (extracellular matrix)-derived three-dimensional (3D) porous acellular scaffold for in vivo tissue engineering nude mice. However, the repair effects of this are still unknown. The aim study was to further explore feasibility application cell-loaded scaffolds, using autologous adipose-derived stem cells (ADSCs), defect rabbits. A 4 mm diameter created on patellar groove femur both knees, and repaired with chondrogenically induced...
Even small cartilage defects could finally degenerate to osteoarthritis if left untreated, owing the poor self-healing ability of articular cartilage.Stem cell transplantation has been well implemented as a common approach in tissue engineering but technical complexity and safety concerns.The stem homing-based technique emerged an alternative promising therapy for repair overcome traditional limitations.In this study, we constructed composite hydrogel scaffold by combining oriented acellular...
Regeneration of an injured meniscus continues to be a scientific challenge due its poor self-healing potential. Tissue engineering provides avenue for regenerating severely damaged meniscus. In this study, we first investigated the superiority five concentrations (0%, 0.5%, 1%, 2%, and 4%) extracellular matrix (MECM)-based hydrogel in promoting cell proliferation matrix-forming phenotype meniscal fibrochondrocytes (MFCs). We found that 2% group strongly enhanced chondrogenic marker mRNA...
The regenerative capacity of the peripheral nervous system is closely related to role that Schwann cells (SCs) play in construction basement membrane containing multiple extracellular matrix proteins and secretion neurotrophic factors, including laminin (LN) brain-derived factor (BDNF). Here, we developed a self-assembling peptide (SAP) nanofiber hydrogel based on backbone Ac-(RADA)
We developed the functionalized self-assembling peptide nanofiber hydrogel RAD/KLT/RGI that was dual-functionalized with VEGF- and BDNF-mimetic epitopes for peripheral nerve regeneration.