A5103025423- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- RNA Research and Splicing
- Musculoskeletal pain and rehabilitation
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Neurogenetic and Muscular Disorders Research
- Nausea and vomiting management
- Anesthesia and Pain Management
- Retinopathy of Prematurity Studies
- Plant Pathogens and Fungal Diseases
- Intraocular Surgery and Lenses
- Restraint-Related Deaths
- Amyotrophic Lateral Sclerosis Research
- Mycorrhizal Fungi and Plant Interactions
- Autoimmune Neurological Disorders and Treatments
- Yeasts and Rust Fungi Studies
- Tattoo and Body Piercing Complications
The University of Texas Health Science Center at Houston
2020-2021
Penn Presbyterian Medical Center
2017
University of Pennsylvania
2017
Massachusetts General Hospital
2016
Harvard University
2016
University of British Columbia
2005
To determine efficacy outcome measures for clinical trials of Leber congenital amaurosis (LCA) associated with a common intronic mutation in the CEP290 gene.CEP290-LCA patients (ages 5-48) (c.2991+1655A>G) were studied as retrospective observational case series using methods and full-field sensitivity testing (FST), optical coherence tomography (OCT), autofluorescence imaging (NIR-RAFI), transient pupillary light reflex (TPLR), oculomotor control instability (OCI), mobility course,...
Mutations in the EYS (eyes shut homolog) gene are a common cause of autosomal recessive (ar) retinitis pigmentosa (RP). Without mammalian model human disease, there is limited understanding details disease expression and rates progression retinal degeneration. We studied clinically with chromatic static perimetry, spectral-domain optical coherence tomography (OCT), en face autofluoresence imaging, cohort 15 patients (ages 12–51 at first visit), some whom had longitudinal data function...
BACKGROUND: Previous studies have suggested that administration of epidural 3% 2-chloroprocaine (CP) before morphine results in decreased analgesic efficacy morphine. We sought to determine whether these observations were a result antagonism or window period between the conclusion surgical anesthesia for cesarean delivery and peak onset time morphine, method preserve exists. METHODS: Term parturients scheduled nonemergent, unscheduled with preexisting labor catheters recruited this...
The hexanucleotide repeat mutation in the intron-1 of chromosome 9 open reading frame (C9orf72) is a frequent cause amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Altered RNA folding plays role ALS pathogenesis two ways: non-ATG translation can lead to aggregates known C9orf72 specific dipeptide polymer, whereas also form neurotoxic inclusions that dose-responsively kill motor neurons. We report presence homology 5'untranslated region (UTR) messenger encoding with...
Lens extraction with endocycloplasty (LE/ECPL) results in greater angle deepening than LE alone plateau iris eyes. This study directly compares an LE/ECPL treatment group a control group.Quantitatively determine the effect of versus for eyes configuration/plateau syndrome (PIC/PIS) on parameters.Patients PIC/PIS who underwent or were reviewed. Eyes ultrasound biomicroscopy-documented PIC that anterior segment optical coherence tomography examination before and after included. Angle...