A5011473176- Reproductive System and Pregnancy
- Bioactive Compounds and Antitumor Agents
- Selenium in Biological Systems
- Psoriasis: Treatment and Pathogenesis
- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Occupational Health and Safety Research
- Drug-Induced Hepatotoxicity and Protection
- Asthma and respiratory diseases
- Ovarian function and disorders
- Natural product bioactivities and synthesis
- T-cell and B-cell Immunology
- Dermatology and Skin Diseases
- Biological Activity of Diterpenoids and Biflavonoids
- Nigella sativa pharmacological applications
- Patient Safety and Medication Errors
- Immunodeficiency and Autoimmune Disorders
- Reproductive Biology and Fertility
- Cholesterol and Lipid Metabolism
- Pregnancy and preeclampsia studies
- Phytochemistry and biological activity of medicinal plants
- Quality and Safety in Healthcare
University of Health Science
2024
Istanbul University
2020-2023
Sağlık Bilimleri Üniversitesi
2020-2023
University of Health Sciences Antigua
2022
Üsküdar University
2022
Necmettin Erbakan University
2015-2019
This research aims to investigate the adverse effects of ZnO NP on ovarian tissue and follicular menstrual cycle protective l-arginine aforementioned tissues.30 rats were divided into five groups. The first group was control group. second fourth groups received 100 mg/kg 200 NP, respectively. third fifth same doses as groups, However, an additional dose 1.3 gr/kg LA amino acid. are given intraperitoneal for 21 days. Blood samples from each rat a part ovarium collected test gene expression...
Endometrial cancer is the most common type of in female reproductive system. Geraniol acyclic monoterpene alcohol derived from essential oils aromatic plants. This study aimed to investigate apoptosis pathway geraniol on Ishikawa cells. The cytotoxic effects cells were determined by an MTT test. seeded cover slips, IC50 dose was applied, and incubated with antibodies against Bax, Bcl-2, TUNEL Assay. mRNA expression analysis apoptosis-related genes RT-qPCR Geraniol. decreased Bcl-2 staining...
Objective: Hyperglycaemia is an important risk factor for the development and progression of macrovascular microvascular complications that occur in diabetes.The expression apoptotic markers aortic medial layer diabetic rats effects N. sativa L. seed oil on these were investigated this study.Methods: Four-month-old adult female Wistar (n=21) divided into 3 groups: Group 1, control; 2, diabetes 3, diabetes+N.sativa oil.Group received 0.2 mg/kg/day (black cumin) intraperitoneally 6 days per...
Objectives: Apigenin and parthenolide as natural products have potent antioxidant anti-inflammatory outcomes that could make them a perfect option for endometriosis therapy. This study aimed to determine the effects of apigenin on created endometrial implants in rat model endometriosis. Methods: Thirty-nine mature, female Sprague-Dawley rats were assigned randomly six experimental groups four weeks after induction. Group 1 (n = 5): Control (CTRL) opened closed abdomen; 2 6): Peritoneal...
Psoriasis is an immune cell-dependent chronic autoimmune skin disorder. Interleukin 37 (IL-37) a cytokine belonging to the IL-1 family that shows anti-inflammatory and protective effects in various mouse models of psoriasis. Even though animal are used investigate pathogenic mechanisms psoriasis, human clinical studies still needed make up for deficiencies, as generally do not exhibit complex phenotypic features Our study aims demonstrate relationship between IL-37-producing tissue-resident...
<title>Abstract</title> Psoriasis, an inflammatory autoimmune disease, arises from intricate interactions between the immune system and epithelium. Recent reports have suggested new roles for gamma delta (γδ) T-cells in addition to surveillance, however, it remains be determined whether mechanisms identified psoriasis murine models a similar role humans. The present study aimed examine relationship IL-17 mRNA level γδ T-cell proliferation clarify their function psoriatic human samples....
Background: To investigate the effects of tannic acid (TA) use on ovarian folliculogenesis, p53 expression, and serum luteinizing hormone (LH), follicle-stimulating (FSH), testosterone (T) levels in rats with polycystic ovary syndrome (PCOS) model. Materials Methods:A total 18 Wistar female were used divided into 3 experimental groups.Group 1 (G1, control), group 2 (G2, PCOS), (G3, PCOS+TA).Rats induced letrozole for 21 days to form a PCOS model.After days, TA (40 mg/kg) was given by gavage...