A5006800696- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles
- Synthesis and Reactivity of Heterocycles
- Synthesis of heterocyclic compounds
- Synthesis and Reactions of Organic Compounds
- Quinazolinone synthesis and applications
- Microwave-Assisted Synthesis and Applications
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis of Organic Compounds
- Cancer therapeutics and mechanisms
- Chemical Reaction Mechanisms
- Chemical Synthesis and Reactions
- Click Chemistry and Applications
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Synthesis of Tetrazole Derivatives
- Chemical Synthesis and Analysis
- Asymmetric Synthesis and Catalysis
- Bioactive Compounds and Antitumor Agents
- Metal complexes synthesis and properties
- Catalytic C–H Functionalization Methods
- Nonlinear Optical Materials Research
Minia University
2015-2025
Kuwait University
2015-2020
King Abdulaziz University
2009-2017
University of Jeddah
2012
The synthesis of polyhydroquinoline derivatives via a four-component unsymmetric Hantzsch reaction induced by solar thermal energy is reported. process proved to be simple, environmentally friendly, economic and high yielding.
In this paper we report the synthesis of some novel 1,2,4-triazolo[1,5-a]pyridine and azolotriazolopyridine ring systems. The products were screened for various types activity like antibacterial, antifungal, antioxidative activity. Compound 13 was found to pose an addition, compound extend life span Caenorhabiditis elegans under standard laboratory conditions reduces both heat chemical induced oxidative stress in C. a dose-dependent manner. Furthermore, treatment worms with significantly...
The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding dihydropyrazolo[5,1-b]quinazolin-8(5H)-ones 4.
A one-pot and clean synthesis of 2-arylbenzothiazoles via the ambient temperature reaction 2-aminothiophenols aromatic aldehydes without catalyst in glycerol as a green solvent has been reported.
A one-pot synthesis of 2-arylbenzothiazoles from the reaction 2-aminothiophenol and aromatic aldehydes catalysed by cerium (IV) ammonium nitrate (CAN) is reported.
Abstract magnified image A simple and efficient three component process for the synthesis of 2‐amino‐2‐chromenes utilizing reaction aryl aldehydes 1a , 1b 1c 1d 1e 1f 1g 1h with active methylenes 2a,b 1‐naphthol 3 in refluxing ethanol/piperidine under microwave‐heating is described. J. Heterocyclic Chem., (2009).
Abstract Green, highly efficient, three-component syntheses of thiazolo-[3,2-a]pyridine derivatives via reaction malononitrile, aromatic aldehydes, and 2-mercaptoacetic acid with a catalytic amount piperidine without solvent molar ratios 2:2:1.2 2:2.2:1, respectively, has been reported.
Abstract A three component synthesis of 2-amino-5,6,7,8-tetrahydro-4-H-chromen-3-carbonitriles using aldehydes, malononitrile, and dimedone in water at ambient temperature was reported.
New 1,2,4-triazole colorants were obtained, in high yields, by coupling 3-ethylthio-5-cyanomethyl-4-phenyl-1,2,4-triazole (1) with diazotized aniline derivatives 2, 4 and 6. The azo dyes prepared this work may exist three tautomeric forms. We found that the tautomerism is influenced mainly nature of substituent at para position component. This tautomerisation was observed NMR spectra dyes. characterized IR, ¹H-NMR, ¹³C-NMR MS spectroscopic techniques.
A convenient, fast and environmentally benign procedure for the synthesis of a new series highly functionalized N-alkylated pyridines as privileged medicinal scaffolds was developed via unique three-component reaction easily available aromatic well heteroaromatic aldehydes, N-alkyl-2-cyanoacetamides malononitrile in EtOH presence K₂CO₃ base promoter under microwave irradiation. The presented tandem process is presumed to proceed Knoevenagel condensation, Michael addition, intramolecular...
Abstract The reaction of o -phenylenediamine with aromatic aldehydes in MeOH at room temperature catalyzed by cerium (IV) ammonium nitrate (CAN) afforded either 2-aryl-1-arylmethyl-1 H -benz-imidazoles and/or 2-aryl-substituted benzimidazoles.
Abstract The reaction of 4-hydroxy-6-methyl-2-pyridone 1 with benzylidenemalononitriles in an ethanolic solution containing a catalytic amount piperidine and α-cyanoacrylic esters pyridine affords the corresponding 4H-pyrano[3,2-c]pyridines. However, it’s 3-(cyanomethylene)-2-indolinones gives either 2-amino-3-quinolinecarbonitriles or ethyl 2-amino-5′,6′-dihydro-7′-methyl-2,5′-dioxospiro-[indoline-3,4′-[4H]-pyrano[3,2-c]pyridine-3′-carboxylate. In contrast,...