A5102863739- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Frailty in Older Adults
- Aging, Elder Care, and Social Issues
- Intergenerational Family Dynamics and Caregiving
- Parkinson's Disease Mechanisms and Treatments
- Health, Environment, Cognitive Aging
- Nutritional Studies and Diet
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Nutrition and Health in Aging
- Global Health Care Issues
- Alzheimer's disease research and treatments
- Mental Health Treatment and Access
- Aging, Health, and Disability
- Blood Pressure and Hypertension Studies
- Fatty Acid Research and Health
- Healthcare Systems and Public Health
- Health, Medicine and Society
- Menopause: Health Impacts and Treatments
- Autism Spectrum Disorder Research
- Folate and B Vitamins Research
- Phytoestrogen effects and research
- Neurological disorders and treatments
- Estrogen and related hormone effects
Hospital de León
2025
Central University of Venezuela
2015-2024
Hospital Clínico Universitario de Caracas
2008-2023
Christian Medical College & Hospital
2009
Universidad Nacional Pedro Henríquez Ureña
2009
King's College London
2009
Instituto Nacional de Neurología y Neurocirugía
2009
Institute of Mental Health
2009
Nnamdi Azikiwe University Teaching Hospital
2008
Qatar Airways (Qatar)
2006
Latin America, China and India are experiencing unprecedentedly rapid demographic ageing with an increasing number of people dementia. The 10/66 Dementia Research Group's title refers to the 66% dementia that live in developing countries less than one tenth population-based research carried out those settings. This paper describes protocols for intervention studies aim redress this imbalance. Cross-sectional comprehensive phase surveys have been conducted all residents aged 65 over...
A set of cross-sectional surveys carried out in Cuba, Dominican Republic, Peru, Mexico, Venezuela, Puerto Rico, China, and India reveal the prevalence between-country variation mild cognitive impairment at a population level.
<h3>Objectives</h3> Despite the growing importance of stroke in developing countries, little is known burden survivors. The authors investigated prevalence self-reported stroke, stroke-related disability, dependence and care-giver strain Latin America (LA), China India. <h3>Methods</h3> Cross-sectional surveys were conducted on individuals aged 65+ (n=15 022) living specified catchment areas. Self-reported diagnosis, care needs giver assessed using a standardised protocol. For those...
The number of older people is set to increase dramatically worldwide. Demographic changes are likely result in the rise age-related chronic diseases which largely contribute years lived with a disability and future dependence. However dependence much less studied although intrinsically linked disability. We investigated prevalence correlates among from middle income countries. A one-phase cross-sectional survey was carried out at 11 sites seven countries (urban Cuba, Venezuela, Dominican...
In countries with high incomes, frailty indicators predict adverse outcomes in older people, despite a lack of consensus on definition or measurement. We tested the predictive validity physical and multidimensional phenotypes settings Latin America, India, China. Population-based cohort studies were conducted catchment area sites Cuba, Dominican Republic, Venezuela, Mexico, Peru, Seven indicators, namely gait speed, self-reported exhaustion, weight loss, low energy expenditure,...
Abstract We evaluated the psychometric properties of 12‐item interviewer‐administered screener version World Health Organization Disability Assessment Schedule – II (WHODAS II) among older people living in seven low‐ and middle‐income countries. Principal component analysis (PCA), confirmatory factor (CFA) Mokken analyses were carried out to test for unidimensionality, hierarchical structure, measurement invariance across 10/66 Dementia Research Group sites. PCA generated a one‐factor...
Current estimates of the prevalence depression in later life mostly arise from studies carried out Europe, North America and Asia. In this study we aimed to measure using a standardised method number low middle income countries (LMIC). A one-phase cross-sectional survey involving over 17,000 participants aged 65 years living urban rural catchment areas 13 sites 9 (Cuba, Dominican Republic, Puerto Rico, Mexico, Venezuela, Peru, China, India Nigeria). Depression was assessed compared ICD-10...
Objectives In a multi‐site population‐based study in several middle‐income countries, we aimed to investigate relative contributions of care arrangements and characteristics carers recipients strain among people with dementia. Based on previous research, hypotheses focused carer sex, inputs, behavioural psychological symptoms (BPSD) socioeconomic status, together potential buffering effects informal support employing paid carers. Methods catchment area surveys 11 sites Latin America, India...
Background The World Health Organization (WHO) has reframed health and healthcare for older people around achieving the goal of healthy ageing. recent WHO Integrated Care Older People (ICOPE) guidelines focus on maintaining intrinsic capacity, i.e., addressing declines in neuromusculoskeletal, vitality, sensory, cognitive, psychological, continence domains, aiming to prevent or delay onset dependence. target group with 1 more capacity (DICs) is broad, implementation may be challenging...
Leveraging the nonmonolithic structure of Latin America, which represents a large variability in social determinants health (SDoH) and high levels genetic admixture, we aim to evaluate relative contributions SDoH ancestry predicting dementia prevalence American populations.
The criterion for dementia implicit in DSM-IV is widely used research but not fully operationalised. 10/66 Dementia Research Group sought to do this using assessments from their one phase diagnostic interview, and validate the resulting algorithm a population-based study Cuba. was operationalised as computerised algorithm, applying clinical principles, based upon cognitive tests, interview informant reports; Community Screening Instrument Dementia, CERAD 10 word list learning animal naming...
Abstract Objective Brief screening tools for dementia use by non‐specialists in primary care have yet to be validated non‐western settings where cultural factors and limited education may complicate the task. We aimed derive a brief version of cognitive informant scales from Community Screening Instrument Dementia (CSI‐D) carry out initial assessments their likely validity. Methods applied Mokken analysis CSI‐D scale data 15 022 participants representative population‐based surveys Latin...
Abstract Background 1) To report site-specific normative values by age, sex and educational level for four components of the 10/66 Dementia Research Group cognitive test battery; 2) to estimate main interactive effects sex, site; 3) investigate effect site region rural or urban location. Methods Population-based cross-sectional one phase catchment area surveys were conducted in Cuba, Dominican Republic, Venezuela, Peru, Mexico, China India. The protocol included administration Community...
Background The proportion of the global population aged 60 and over is increasing, more so in Latin America than any other region. Depression common among elderly people an important cause disability worldwide. Aims To estimate prevalence correlates late-life depression, associated access to treatment five locations America. Method A one-phase cross-sectional survey 5886 65 from urban rural Peru Mexico site Venezuela. was identified according DSM–IV ICD–10 criteria, Geriatric Mental...
Abstract Background To describe patterns of recent health service utilisation, and consequent out-of-pocket expenses among older people in countries with low middle incomes, to assess the equity which services are accessed delivered. Methods 17,944 aged 65 years over were assessed one-phase population-based cross-sectional surveys geographically-defined catchment areas nine - urban rural sites China, India, Mexico Peru, Cuba, Dominican Republic, Puerto Rico Venezuela, a site Nigeria. The...
Objectives To estimate the prevalence, social patterning, treatment and control of hypertension among older people in 10/66 Dementia Research Group developing country sites. Methods Cross-sectional surveys SBP, hypertension, awareness, 17 014 aged 65 years over eight urban four rural sites Latin America, India China. Results Hypertension prevalence was higher (range 52.6–79.8%) than 42.6–56.9%), lower men women [pooled ratio 0.89, 95% confidence interval (CI) 0.85–0.93]. Educational...
This study was designed to explore prevalence and correlates of self-reported loneliness investigate whether predicts mortality among older adults (aged 65 or above) in Latin America, China India.
Evidence of an association between fish and meat consumption risk dementia is inconsistent nonexistent in populations developing countries.The objective was to investigate associations with low- middle-income countries.One-phase cross-sectional surveys were conducted all residents aged > or =65 y 11 catchment areas China, India, Cuba, the Dominican Republic, Venezuela, Mexico, Peru. A total 14,960 assessed by using 10/66 standardized protocol, which includes face-to-face interviews for...
Even in low and middle income countries most deaths occur older adults. In Europe, the effects of better education home ownership upon mortality seem to persist into old age, but these may not generalise LMICs. Reliable data on causes determinants are lacking.The vital status 12,373 people aged 65 y over was determined 3-5 after baseline survey sites Latin America, India, China. We report crude standardised rates, standardized ratios comparing experience with that United States, estimated...