A5076609292- Liver Disease Diagnosis and Treatment
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Helicobacter pylori-related gastroenterology studies
- Metabolism and Genetic Disorders
- Congenital gastrointestinal and neural anomalies
- Long-Term Effects of COVID-19
- Drug-Induced Hepatotoxicity and Protection
- Gut microbiota and health
- Eosinophilic Esophagitis
- Blood Pressure and Hypertension Studies
- Viral gastroenteritis research and epidemiology
- Diet and metabolism studies
- Pathogenesis and Treatment of Hiccups
- Diet, Metabolism, and Disease
- Gastrointestinal disorders and treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Gout, Hyperuricemia, Uric Acid
- Cardiovascular Syncope and Autonomic Disorders
- Eicosanoids and Hypertension Pharmacology
- Hormonal Regulation and Hypertension
- Healthcare Systems and Public Health
S. M. Kirov Military Medical Academy
2022-2025
Military Medical Academy
2023-2024
Central State Medical Academy
2021
Sechenov University
2017-2020
Currently, with the abundance of scientific information, specialists face questions in interpreting repolarization disturbances for formulating an electrocardiographic diagnosis. The formulations accepted domestic electrocardiography methodology, such as “focal changes myocardium” coronary blood flow disorders, and “diffuse nonspecific disturbances, are not always related to pathology. Furthermore, there is confusion ECG signs ischemia and/or myocardial damage article reviews modern criteria...
Rationale: The relevance of the problem is related to lack data on Helicobacter pylori (HP) prevalence in Russia, which associated with risk peptic ulcer and gastric cancer, also, other hand, non-adherence doctors existing expert guidelines diagnosis this infection HP eradication therapy. Aim: To assess among medical workers their willingness undergo Materials methods: A total 315 (61 men 254 women) aged 18 76 years were examined, them 221 Moscow 94 Kazan. contamination rate, all...
Background. The novel coronavirus infection COVID-19 can be manifested by damage to the organs of gastrointestinal tract (GIT). Damage SARS-CoV-2 virus leads a violation microbial-tissue complex mucous membrane digestive tract. A common gastroenterological manifestation is diarrhea. Aim. Study clinical features disorders and possibility optimizing treatment diarrheal syndrome in patients with mild form viral infection. Materials methods. observation group consisted 230 COVID-19: K-group...
Low patient compliance due to the development of adverse events in form antibiotic-associated diarrhea (AAD) is considered as main reason for failure eradication optimized anti-Helicobacter therapy regimens. A key mechanism AAD reduce number and species diversity bacteria that butyric acid. Aim. The purpose this study was comparative effect on clinical effectiveness (ET) Helicobacter pylori infection metabolic changes colon microbiota additional inclusion treatment regimen combined prebiotic...
In the clinical classification of cholelithiasis, biliary sludge (BS) is distinguished as pre-stone stage. Ursodeoxycholic acid (UDCA) a drug with an evidence base for effective and safe effects on BS. The therapeutic equivalence various UDCA drugs remains important issue practice. Aim. To conduct comparative analysis effectiveness use UDCA: Ursofalk other treatment BS in fixed dose 10 mg/kg body weight. Material methods. observation group consisted 225 patients types randomized groups,...
Introduction . In recent years, diarrheal syndrome is the most common clinically significant negative effect of antibiotic therapy (ABT), which constitutes a first-priority medical and social problem. The prescription any for duration treatment may cause potential risk developing antibiotic-associated diarrhea (AAD). that regard, there need systematization main pathogenetic aspects deveopment AAD rationale use probiotics to prevent its development treatment. Aim To conduct comparative...
Cardiovascular diseases remain a heavy socioeconomic burden in the modern world, claiming up to four million lives annually, including one of Russian population. Most often, cardiovascular mortality is associated with chronic coronary heart disease and its complications. Despite progress treatment acute syndrome phase, problem recurrent events adequate rehabilitation remains unresolved. Modern European recommendations for present main directions secondary prevention myocardial infarction,...
COVID-19 infection may present with gastrointestinal lesions in up to 25% of patients. One the target organs SARS-CoV-2 virus is intestine. The pathogenesis intestinal damage a new coronavirus remains unclear and requires further in-depth study. Possible mechanisms include direct cytotoxic effect virus, persistent reduction butyrate-producing bacteria, side effects drugs, Clostridioides difficile infection, microvascular thrombosis, immune-mediated inflammatory reactions most common symptom...
Background. Symptomatic uncomplicated diverticular colon disease (SNDCD) is a common condition that significantly affects the quality of life patients. One main therapeutic targets in SNDCD microbiota.
 Aim. To evaluate efficacy and safety microbiocenosis-based therapy (prebiotic Mucofalk + metabiotic Zakofalk) relieving symptoms maintaining asymptomatic remission.
 Materials methods. The study included 60 patients with clinically apparent SNDCD. For 3 months, they were treated...
Symptoms of constipation such as derangements the motor, secretory and/or evacuation functions colon are recorded occasionally or for a long period in at least 20% population economically developed countries. QoL is significantly impaired patients with chronic constipation. The frequency, time bowel movement and stool consistency is, large part, determined by motor function colon. primary approach to treatment algorithm (CC) modification lifestyle diet rich dietary fiber. If measures provide...
The current study describes pharmacological features and benefits of using the angiotensin II receptor blocker telmisartan in actual clinical practice. This bifunctional agent has a number unique pharmacokinetic features: longest duration action, high lipophilicity maximum efficiency PPARy activation. results numerous studies confirmed efficacy ability to control blood pressure during day early-morning hours compared other antihypertensive drugs. main pleutrophic effects have been proven at...
The current study describes pharmacological features and benefits of using the angiotensin II receptor blocker telmisartan in actual clinical practice. This bifunctional agent has a number unique pharmacokinetic features: longest duration action, high lipophilicity maximum efficiency PPARy activation. results numerous studies confirmed efficacy ability to control blood pressure during day early-morning hours compared other antihypertensive drugs. main pleutrophic effects have been proven at...
Aim. To evaluate the clinical efficacy of laxatives with different pharmacological effects in combination therapy patients chronic constipation (CC) concurrent obesity, hypertensive disease, and type 2 diabetes mellitus (DM). Subjects methods. A total 110 people (45 men, 65 women) aged 45 to 72 years CC presence concomitant diseases: grade 1 or disease + obesity DM. The investigators determined severity abdominal pain syndrome flatulence, by indicating mean frequency defecations per week...
The article presents the data and review of North American Consensus (2017) recommendations on use hydrogenmethane breathing test in diagnosing gastrointestinal disorders accompanied by excessive bacterial growth small intestine. On May 16, 2015, 17 leading scientists specializing tests took part a consensus meeting Washington (DC, USA). By voting method, 28 statements were identified given following issues regarding hydrogen-methane procedure itself gastroenterological practice: 1)...
Aim. To assess safety and effectiveness of combination therapy by simvastatin with ursodezoxycholic acid in treatment dyslipidemia coronary heart disease patients. Material methods. Totally 30 CHD patients (stable angina, 2nd functional class — 2FC) having metabolic syndrome (MS) had (20 mg/day) (Ursosan daily dose 15 mg per kg) during days. For all included the non-alcoholic steatohepatits (NASH) was confirmed. Of them 25 (85%) clinical predictors fibrosis liver cirrhosis. All abnormal...