- Escherichia coli research studies
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Probiotics and Fermented Foods
- Enterobacteriaceae and Cronobacter Research
- Urinary Tract Infections Management
- Gut microbiota and health
- Antibiotic Resistance in Bacteria
- Infant Nutrition and Health
- Listeria monocytogenes in Food Safety
- Animal health and immunology
- Pediatric health and respiratory diseases
- Regional Development and Innovation
- Plant Virus Research Studies
- Salmonella and Campylobacter epidemiology
- Parvovirus B19 Infection Studies
- Nosocomial Infections in ICU
- Monoclonal and Polyclonal Antibodies Research
- Bacterial Genetics and Biotechnology
- Essential Oils and Antimicrobial Activity
- Pharmaceutical studies and practices
- Pediatric Pain Management Techniques
- Streptococcal Infections and Treatments
- Zoonotic diseases and public health
- Aquaculture disease management and microbiota
Hospital Infantil de México Federico Gómez
2016-2025
Universidad Nacional Autónoma de México
2012-2024
Centro Médico ABC
2024
Departamento de Salud
2019-2023
Mexican Social Security Institute
2023
Public Health Department
2020
Cronobacter spp. are opportunistic pathogens linked to lie-threatening infections in neonates and contaminated powdered infant formula that has been epidemiologically associated with these cases. Clinical symptoms of include necrotizing enterocolitis, bacteremia, meningitis. Flagella from C. sakazakii involved biofilm formation its adhesion epithelial cells. We investigated the role flagella ST1 ST4, malonaticus, muytjensii, turicensis dublinensis during activation cytokines (IL-8, TNF-α,...
Lactobacilli species are an effective biotherapeutic alternative against bacterial infections and intestinal inflammatory disorders. However, it is important to evaluate their beneficial properties, before considering them as probiotics for medical use. In this study we evaluated some probiotic properties of Lactobacillus rhamnosus GG, KLSD, helveticus IMAU70129, casei IMAU60214 previously isolated from dairy products control Shirota. Experimental evaluations revealed that all strains...
Abstract Urinary tract infections (UTIs) are mainly caused by uropathogenic Escherichia coli (UPEC), whose impact can be exacerbated multidrug-resistant (MDR) strains. Effective control strategies are, therefore, urgently needed. Among them, phage therapy represents a suitable alternative. Here, we describe the isolation and characterization of novel phages from wastewater samples, as well their lytic activity against biofilm adherence UPEC to HEp-2 cells. The results demonstrated that...
Worldwide, Urinary Tract Infections (UTIs) are an important health problem with many cases reported annually, women being the most affected. UTIs relevant because they can become a recurrent condition, associated different factors that contribute to chronicity of disease (cUTI). cUTI be classified as persistent (peUTI) when causative agent is same each time infection occurs or reinfection (reUTI) microorganism different. The purpose this work was characterize Escherichia coli isolates...
Overuse of antimicrobials has greatly contributed to the increase in emergence multidrug-resistant bacteria, a situation that hinders control and treatment infectious diseases. This is case with urinary tract infections (UTIs), which represent substantial percentage worldwide public health problems, thus need look for alternatives their treatment. Previous studies have shown usefulness autologous bacterial lysates as an alternative UTIs. However, limitation high cost producing individual...
Epidemics and pandemics of cholera, a diarrheal disease, are attributed to Vibrio cholera serogroups O1 O139. In recent years, specific lytic phages V. have been proposed be important factors in the cyclic occurrence endemic areas. However, role potential participation during long interepidemic periods non-endemic regions not yet described. The purpose this study was isolate characterize strains.Sixteen were isolated from wastewater samples collected at Endhó Dam Hidalgo State, Mexico,...
Urinary tract infection (UTI) is a relevant public health problem, economically and socially affecting the lives of patients. The increase antimicrobial bacterial resistance significantly hinders treatment UTIs, raising need to search for alternative therapies. Bacterial lysates (BL) obtained from Escherichia coli other pathogens have been used treat different infectious diseases with promising results. This work aims evaluate effect composition an autologous BL control recurrent UTIs in...
Enteroaggregative Escherichia coli (EAEC) and enterohemorrhagic E. (EHEC) are pathotypes associated with unmanageable diarrhea in children adults. An alternative to the treatment of infections caused by these microorganisms is use bacteria Lactobacillus genus; however, beneficial effects on intestinal mucosa specific strain species. The interest this study consisted analyzing coaggregation properties casei IMAU60214, as well effect cell-free supernatant (CSF) growth anti-cytotoxic activity a...
Pet is a toxin from the family of Serine Protease Autotransporters Enterobacteriaceae which was initially identified in Enteroaggregative Escherichia coli strains. This protease exhibits enterotoxin properties, damages cell cytoskeleton and induces intestinal epithelium alterations, are associated with severe inflammatory process. An in-vitro study conducted to evaluate effect on migration human peripheral blood monocytes-derived macrophages its participation activation early response...
ABSTRACT In Mexico, diarrheal disease due to different serotypes of Escherichia coli is highly prevalent, with only sporadic isolation O157 non-H7 strains. This could be exposure the or related E. lipopolysaccharide (LPS), such as O7 O116, at an early age. By using enzyme-linked immunosorbent assay (ELISA) and Western blotting, present study analyzed 605 serum samples from Mexican adults infants without clinical symptoms for presence antibodies these three LPSs. The bactericidal activities...
Uropathogenic Escherichia coli (UPEC) are the main etiological agent of urinary tract infections (UTIs). Association between different serotypes and UTIs is known, however, some strains incapable to be serotyped. The aim this work was study bthe phenotypical genotypical characteristics 113 non-typeable (NT) auto-agglutinating (AA) E. strains, isolated from in children adults.The UPEC were analyzed by PCR assays using specific primers determine their serogroups, fimH, papC, iutA, sat, hlyCA...
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COVID-19 is an infectious disease caused by SARS-CoV-2; over the course of disease, a dysregulated immune response leads to excessive inflammation that damages lung parenchyma and compromises its function. One cell lineages classically associated with pathological inflammatory processes mast cells (MCs). MCs their mediators have been COVID-19; we previously reported role carboxypeptidase A3 (CPA3) in severe COVID-19. However, sequelae SARS-CoV-2 infection poorly studied. In patients who...
This study reports the effects of exposing cells prototypical enteropathogenic Escherichia coli (EPEC) strain E2348/69 to static magnetic fields (SMF) varying intensities observe their capacity autoaggregate and effect on cell adherence. The results showed that bacteria exposure over course 5 min an intensity 53 mT reduced autoaggregation by 28%. However, with up 100 same time, was approximately 50%; after 30 at intensity, it indistinguishable from observed in a non-autoaggregative strain....
Antimicrobial bacteria resistance is an important problem in children with recurrent urinary tract infections (rUTI), thus it crucial to search for alternative therapies. Autologous bacterial lysates (ABL) may be a potential treatment rUTI. Twenty-seven rUTI were evaluated one year, urine and stool cultures performed, 10 colonies of each culture selected those identified as