Anthony J. Comerota

ORCID: 0000-0003-4711-6281
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About
Contact & Profiles
Research Areas
  • Venous Thromboembolism Diagnosis and Management
  • Diagnosis and Treatment of Venous Diseases
  • Central Venous Catheters and Hemodialysis
  • Peripheral Artery Disease Management
  • Cerebrovascular and Carotid Artery Diseases
  • Vascular Procedures and Complications
  • Acute Ischemic Stroke Management
  • Atrial Fibrillation Management and Outcomes
  • Aortic aneurysm repair treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Health and Disease Prevention
  • Vascular anomalies and interventions
  • Blood Coagulation and Thrombosis Mechanisms
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Acute Myocardial Infarction Research
  • Aortic Disease and Treatment Approaches
  • Intracranial Aneurysms: Treatment and Complications
  • Coronary Interventions and Diagnostics
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Ultrasound in Clinical Applications
  • Case Reports on Hematomas
  • Hemodynamic Monitoring and Therapy
  • Cardiac Arrhythmias and Treatments
  • Angiogenesis and VEGF in Cancer
  • Protease and Inhibitor Mechanisms

Inova Alexandria Hospital
2018-2025

Temple University
1996-2023

Alaska Heart and Vascular Institute
2019-2022

Inova Health System
2020-2021

ProMedica Toledo Hospital
2009-2020

Mercy St. Vincent Medical Center
2019

Temple University Hospital
1993-2018

University of Michigan
2005-2017

University of the Philippines Manila
2017

Mayo Clinic
2015

The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical thrombolysis") rapidly removes thrombus and is hypothesized to reduce the risk of syndrome.

10.1056/nejmoa1615066 article EN New England Journal of Medicine 2017-12-06

Claudication is a common and disabling symptom of peripheral artery disease that can be treated with medication, supervised exercise (SE), or stent revascularization (ST).We randomly assigned 111 patients aortoiliac to receive 1 3 treatments: optimal medical care (OMC), OMC plus SE, ST. The primary end point was the change in peak walking time on graded treadmill test at 6 months compared baseline. Secondary points included free-living step activity, quality life Walking Impairment...

10.1161/circulationaha.111.075770 article EN Circulation 2011-11-17

Background: The ATTRACT trial (Acute Venous Thrombosis: Thrombus Removal with Adjunctive Catheter-Directed Thrombolysis) previously reported that pharmacomechanical catheter–directed thrombolysis (PCDT) did not prevent postthrombotic syndrome (PTS) in patients acute proximal deep vein thrombosis. In the current analysis, we examine effect of PCDT iliofemoral Methods: Within a large multicenter randomized trial, 391 thrombosis involving iliac or common femoral veins were to anticoagulation...

10.1161/circulationaha.118.037425 article EN Circulation 2019-01-17

Background and Objectives Intermittent pneumatic compression (IPC) is an effective form of deep vein thrombosis prophylaxis for general surgery patients. The antithrombotic effect IPC thought to be the result increased venous velocity stimulation endogenous fibrinolysis. However, mechanism enhanced fibrinolytic activity relative effects on normal postthrombotic veins have not been defined. purposes this study are 1) quantify changes in with IPC; 2) enhancement 3) evaluate whether patients...

10.1097/00000658-199709000-00010 article EN Annals of Surgery 1997-09-01

A randomized, parallel-group, open-label clinical trial (the physicians, patients, and staff were not blinded with regard to the regimen that had been used) was conducted, between December 1988 September 1990, compare safety efficacy of enoxaparin, a low-molecular-weight heparin, unfractionated heparin for prevention deep venous thrombosis after elective hip replacement. Six hundred ten patients 607 received one study medications. The evaluations included contrast-media venography,...

10.2106/00004623-199401000-00002 article EN Journal of Bone and Joint Surgery 1994-01-01
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