A5012153920- Microbial infections and disease research
- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- Cancer Cells and Metastasis
- Diet and metabolism studies
- Herpesvirus Infections and Treatments
- Cardiovascular Conditions and Treatments
- Liver Disease Diagnosis and Treatment
- 3D Printing in Biomedical Research
- Neuropeptides and Animal Physiology
- Pluripotent Stem Cells Research
- Helicobacter pylori-related gastroenterology studies
- Mycobacterium research and diagnosis
- Gastrointestinal motility and disorders
- Respiratory viral infections research
- Liver physiology and pathology
- Tissue Engineering and Regenerative Medicine
- Animal health and immunology
- Adipose Tissue and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Diet, Metabolism, and Disease
- Veterinary Oncology Research
- Planarian Biology and Electrostimulation
- Renal function and acid-base balance
- Viral Infections and Vectors
Iowa State University
2019-2025
SMART Reading
2023-2024
The Metabolomics Innovation Centre
2023
University of Alberta
2023
Mitchell Institute
2023
Texas A&M University
2023
While two-dimensional (2D) cell cultures, such as Caco-2 and Madin-Darby canine kidney (MDCK) cells are widely used in a variety of biological models, these vitro systems present inherent limitations replicating the complexities vivo biology. Recent progress three-dimensional organoid technology has potential to address limitations. In this study, characteristics conventional 2D culture were compared those intestinal organoids (enteroids, ENT colonoids, COL). Light microscopy transmission...
While two-dimensional (2D) cell cultures, such as Caco-2 and Madin–Darby canine kidney (MDCK) cells are widely used in a variety of biological models, these vitro systems present inherent limitations replicating the complexities vivo biology. Recent progress three-dimensional organoid technology has potential to address limitations. In this study, characteristics conventional 2D culture were compared those intestinal organoids (enteroids, ENT, colonoids, COL). Light microscopy transmission...
This study aimed to assess the morphometry of enterocytes as well goblet cell-to-enterocyte ratio in different intestinal segments dogs with chronic enteropathies (CE). Histopathological samples from 97 were included (19 healthy juveniles, 21 adults, 24 protein-losing enteropathy (PLE), and 33 CE without PLE). Healthy adult small showed progressively reduced epithelial cell height aboral direction, while juvenile increased direction. had duodenum, PLE decreased heights compared dogs. Both...
Mycoplasma hyorhinis (MHR) and hyosynoviae (MHS) are common opportunistic pathogens in the upper respiratory tract tonsils of swine. The identification specific species involved clinical cases using conventional diagnostic methods is challenging. Therefore, a recombinant chimeric polypeptide based on seven known variable lipoproteins (A-G) MHR cocktail surface proteins detergent-extracted from MHS cultures were generated their suitability as antemortem biomarkers for serodiagnosis MHR-...
Mycoplasma hyopneumoniae is an economically significant pathogen of swine. M. serum antibody detection via commercial enzyme-linked immunosorbent assays (ELISAs) widely used for routine surveillance in swine production systems. Samples from two studies were to evaluate assay performance. In study 1, 6 ELISAs compared using samples 8-week-old cesarean-derived, colostrum-deprived (CDCD) pigs allocated the following 5 inoculation groups 10 each: (i) negative control, (ii) flocculare (strain...
Organoids are 3-dimensional (3D) self-assembled structures capable of replicating the microanatomy and physiology epithelial components their organ origin. Adult stem cell (ASC) derived organoids from liver have previously been shown to differentiate into primarily mature cholangiocytes, partial differentiation functional hepatocytes can be promoted using specific media compositions. While full morphological ASCs has not yet reported for any species, approximated various Six formulations...
<title>Abstract</title> <bold>Background and Purpose</bold> Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk factors, chronic kidney disease, cardiovascular system. A growing body of literature suggests that syndrome (<italic><bold>MetS</bold></italic>) in individuals normal weight is associated with a high prevalence diseases an increased mortality. The aim this study was to establish non-invasive preclinical model <italic><bold>MetS</bold></italic>...
Benazepril exhibits a dose-dependent effect on biomarkers of the circulating renin-angiotensin-aldosterone system (RAAS) in dogs.
Accumulating data from several large, placebo-controlled studies suggests that sodium-glucose transporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 receptor (GLP-1) agonists offer therapeutic benefits in the management of cardiovascular diseases, regardless patient’s diabetic status. In addition to their effects on glucose excretion, SGLT2 have a positive impact systemic metabolism. The aim this study was establish non-invasive preclinical model metabolic syndrome (MetS) investigate...
Abstract Accumulating data from several large, placebo-controlled studies suggests that sodium-glucose transporter 2 (SGLT-2) inhibitors and glucagon-like peptide 1 receptor (GLP-1) agonists offer therapeutic benefits in the management of cardiovascular diseases, regardless patient's diabetic status. In addition to their effects on glucose excretion, SGLT2-inhibitors have a positive impact systemic metabolism by reducing inflammation oxidative stress, shifting towards ketone body production,...