Object. The authors introduce a unique computer-assisted cervical pedicle screw (CPS) insertion technique used in conjunction with specially modified original instruments. accuracy of placement as well surgery-related outcome and complication rates were compared between two groups patients: those whom conventional manual was used. Methods. guiding system consisted awl, probe, tap screwdriver designed for CPS insertion. Using this system, real-time instrument/screw tip information three...

The ideal cell-carrier material for cartilage regeneration should be one that closely mimics the natural environment in a living articular matrix. In current study, we considered alginate-based chitosan hybrid biomaterials could provide excellent supports chondrocyte adhesion. To test this hypothesis, investigated adhesion behavior of rabbit chondrocytes onto an alginate polymer versus some fibers vitro. We demonstrated showed much improved capacity with comparison fiber. Additionally,...

There have been few reports on the long-term outcomes after operative treatment of missed Monteggia fracture-dislocations in children. The purpose present study was to evaluate clinical and radiographic open reduction for a fracture-dislocation.We postoperatively investigated twenty-two children with fracture. group included fourteen boys eight girls who had mean age ten years (range, four fifteen eleven months) at time reduction. Each patient managed radial head combined posterior bending...

Bisphosphonate medications are widely used for the treatment of osteoporosis, but they might disturb healing process spinal fusion. The object this prospective randomized controlled study was to evaluate effect bisphosphonate medication on fusion through radiographic, clinical, and biological assessments.A total 40 patients with osteoporosis who were candidates single-level posterior lumbar interbody randomly assigned alendronate group (alendronate sodium 35 mg/week) or control (vitamin D,...

Abstract Siglecs are a family of sialic acid–binding immunoglobulin-like lectins that regulate the functions cells in innate and adaptive immune systems through glycan recognition. Here we show Siglec-15 regulates osteoclast development bone resorption by modulating receptor activator nuclear factor κB ligand (RANKL) signaling association with DNAX-activating protein 12 kDa (DAP12), an adaptor bearing immunoreceptor tyrosine-based activation motif (ITAM). Among known expressed myeloid...

The results and complications of 104 vascularised fibular grafts in 102 patients are presented. Bony union was ultimately achieved 97 patients, with primary 84 (84%). mean time to 15.5 weeks (8 40). In 13 at one end the fibula secondary other end. these 31.1 (24 Five failed achieve union, a resultant pseudarthrosis (3 patients) or amputation (2 patients). There were various complications. Immediate thrombosis occurred 14 cases. two 23 osteomyelitis, infection recurred six months after...

Background The current surgical procedures for irreparable rotator cuff tears have considerable limitations. Tissue engineering techniques using novel scaffold materials offer potential alternatives managing these conditions. Hypothesis A chitosan-based hyaluronan hybrid could enhance type I collagen products with seeded fibroblasts and thereby increase the mechanical strength of regenerated tendon in vivo. Study Design Controlled laboratory study. Methods scaffolds were created from polymer...

Abstract In this study, we successfully developed three‐dimensional scaffolds fabricated from the chitosan‐based hyaluronic acid hybrid polymer fibers, which can control porous structure. To determine adequate pore size for enhancing chondrogenesis of cultured cells, compared behaviors rabbit chondrocytes in comprising different sizes (100, 200, and 400 μm size). Regarding cell proliferation, there was no significant difference among three groups. On other hand, glycosaminoglycan contents...

Although autologous osteochondral mosaicplasty is widely used as a procedure for osteochondritis dissecans lesions, the effectiveness of this in elbow lesions remains unclear. Our aim was to clarify surgical efficacy teenage athletes with advanced capitellar dissecans.From 2001 2006, nineteen male patients who were competitive and had underwent mosaicplasties. The mean age 14.2 years. technique involved obtaining small-sized cylindrical grafts diameter 3.5 mm from lateral periphery femoral...

In Brief Study Design. Clinical results of posterolateral endoscopic debridement and irrigation followed by percutaneous drainage for pyogenic spondylodiscitis were analyzed. Objectives. To report clinical transforaminal surgery to evaluate the effectiveness this procedure in treatment spinal infections. Summary Background Data. Pyogenic infections have been increasing due development medical patients with comorbid problems. Common treatments are administration antibiotics or surgical bone...

Autologous osteochondral mosaicplasty is a new technique to provide hyaline repair for articular defects. Although recent studies have reported the successful treatment of defects in knee and ankle joints with this surgical procedure, little attention has been given efficacy osteochondritis dissecans humeral capitellum.To clarify clinical outcomes teenaged patients advanced lesions capitellar dissecans.Case series; Level evidence, 4.Eight underwent mosaicplasties. All were baseball players...

Abstract To clarify the feasibility of using novel chitosan‐based hyaluronan hybrid polymer fibers as a scaffold in ligament tissue engineering, their mechanical properties and ability to promote cellular adhesion, proliferation, extracellular matrix production were studied vitro . Chitosan 0.05% 0.1% developed by wet spinning method. Hyaluronan coating significantly increased properties, compared chitosan fibers. Rabbit fibroblasts adhesion onto was greater than for control For analysis...

In Brief Study Design. The accuracy of pedicle screw placement was evaluated in posterior scoliosis surgeries with or without the use computer-assisted surgical techniques. Objective. this retrospective cohort study, surgery compared between conventional fluoroscopic and Summary Background Data. There has been no study systemically analyzing perforation pattern comparative surgery. Methods. 45 patients who received correction were divided into 2 groups: Group C, manual control (25 patients);...

In Brief Study Design. A retrospective review. Objective. This study examined the clinical outcomes of circumferential spinal cord decompression through a posterior approach for thoracic ossification longitudinal ligament (OPLL), to determine efficacy this procedure and incidence complications. Summary Background Data. Since decompressive laminectomy is not always effective in treatment myelopathy caused by OPLL, single seems offer an option. However, technically demanding has high risk...

One significant disadvantage of autologous osteochondral mosaicplasty (mosaicplasty) is the harvesting grafts from normal articular area knee joint. However, effect on function remains unclear.To clarify functional effects donor and to perform magnetic resonance imaging evaluation site repair after for capitellar osteochondritis dissecans in young athletes.Case series; Level evidence, 4.Eleven male competitive athletes with advanced lesions underwent mosaicplasties. The surgical technique...

Although the etiology of intervertebral disc degeneration is poorly understood, one possible approach for its regulation apoptosis inhibition. This study was undertaken to investigate antiapoptotic effects caspase 3 in rabbits.We investigated small interfering RNA (siRNA) on rabbit nucleus pulposus cells a serum-starved medium. The direct injection Alexa Fluor 555-labeled siRNA into were also determined vivo using anular needle puncture model.Rabbit transfected with showed significant...

The objective of this study was to conduct a follow-up evaluation an arthroscopic reattachment technique using avulsed deep component the triangular fibrocartilage complex (dc-TFCC) from fovea distal ulna (ulnar fovea).A retrospective performed on consecutive cohort 12 patients who underwent dc-TFCC into ulnar over 24-month period. mean age 31 years (range, 20 50 years). There were 6 men and women. This anchors portion by means repair suture passed through created osseous tunnel neck foveal...

Object The posterior ligamentous complex (PLC) in the thoracic and lumbar spine is one of region's important stabilizers. precise diagnosis PLC injury required to evaluate instability injured spine; however, accuracy magnetic resonance (MR) imaging for diagnosing has remained unclear. In this study, authors compared preoperative MR findings with direct intraoperative observation injury, clarifying former's diagnostic regarding detection associated fractures. Methods Data obtained 35 patients...