A5038152327- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Vascular Tumors and Angiosarcomas
- Lymphoma Diagnosis and Treatment
- Musculoskeletal synovial abnormalities and treatments
- Orthopaedic implants and arthroplasty
- Management of metastatic bone disease
- Cancer Diagnosis and Treatment
- Cardiac tumors and thrombi
- Total Knee Arthroplasty Outcomes
- Chronic Lymphocytic Leukemia Research
- Hematological disorders and diagnostics
- Orthopedic Infections and Treatments
- CAR-T cell therapy research
- Oral and Maxillofacial Pathology
- Reconstructive Surgery and Microvascular Techniques
- Shoulder and Clavicle Injuries
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Shoulder Injury and Treatment
- Bone health and treatments
- Elbow and Forearm Trauma Treatment
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Chronic Myeloid Leukemia Treatments
AULSS 2 Marca Trevigiana
2023
Ospedale di Monfalcone
2020-2021
Istituto di Sociologia Internazionale di Gorizia
2006-2020
Nuovo Ospedale San Giovanni di Dio
2011
Centro di Riferimento Oncologico
2001
Istituto di Ematologia di Bologna
1986-2000
Istituto Ortopedico Rizzoli
1986-1999
Istituto Oncologico Romagnolo
1988-1998
University of Bologna
1983-1995
Orthopedic Institute
1994
PURPOSE: Adjuvant chemotherapy for soft tissue sarcoma is controversial because previous trials reported conflicting results. The present study was designed with restricted selection criteria and high dose-intensities of the two most active chemotherapeutic agents. PATIENTS AND METHODS: Patients between 18 65 years age grade 3 to 4 spindle-cell sarcomas (primary diameter ≥ 5 cm or any size recurrent tumor) in extremities girdles were eligible. Stratification by primary versus tumors tumor...
Background. Neoadjuvant chemotherapy is the most accepted treatment for localized osteosarcoma. This has led to a great improvement in limb-sparing surgery and disease-free survival. Patients with good response preoperative showed higher survival rate. Current studies examine possibility of patients whose limbs could be rescued poor necrosis reduction side effects related aggressive treatments. Methods. Between September 1986 December 1989, 164 entered second neoadjuvant study conducted at...
BACKGROUND Synovial sarcoma, one of the most common soft tissue sarcomas that occur in adolescents and young adults, is generally viewed treated as a high grade sarcoma. However, authors' own experience some previous studies have indicated it has wide spectrum biologic behavior low risk subgroups patients with synovial sarcoma can be identified. METHODS A total 121 consecutive (including 66 males 55 females ages 9–74 years), primarily or secondarily at 2 large referral centers for...
The predominant sites of viable and nonviable tumor were determined in the primary lesions 50 patients with osteosarcoma after initial treatment preoperative chemotherapy. degree destruction was classified as good, fair, poor a map revealing constructed. study revealed several preferential where likely to persist: soft tissues, cortex, subcortex, ligaments, areas contact cartilage (growth plate and/or articular cartilage). Localized hemorrhage necrosis, designated "lacunae," noted within...
Between March 1983 and June 1986 127 patients with localized osteosarcoma of the extremity were treated neoadjuvant chemotherapy. Preoperative chemotherapy consisted two cycles methotrexate (MTX) (high or moderate doses) followed by 6 days cisplatin (CDP). Surgery was an amputation a rotation plasty, limb salvage. Necrosis good in 52% cases, fair 36%, poor 12%. Postoperative Adriamycin (doxorubicin [ADM]) bleomycin (BCD) for responders; ADM, MTX, CDP responders. Good responders as only MTX...
We reviewed the records of all patients with diagnosis chondromyxoid fibroma at Bone Tumor Center Istituto Ortopedico Rizzoli. The twenty-seven were available for study clinical, radiographic, and pathological findings Surgical treatment was evaluated in twenty two a follow-up longer than years; their average 117 months (range, twenty-four to 380 months) Seventeen had been followed least five years. A questionnaire including request radiographs questions pertaining directly functional status...
Giant-cell tumor of bone is predominantly an affliction adults and rarely found in skeletally immature patients. We are reporting six new cases histologically confirmed giant-cell patients with radiographically open epiphyseal plates. These account for 1.8 per cent the 326 observed at Bone Tumor Center Istituto Ortopedico Rizzoli Bologna, Italy.
A new trial for evaluating the effectiveness of adjuvant chemotherapy in high-grade soft-tissue sarcomas extremities adult patients is presented. All after local treatment were randomized into two arms, one without further therapy and other to receive (Adriamycin [Farmitalia-Carlo Erba, Milan, Italy], 450 mg/m2). The preliminary results study are reported at a median observation period 27.6 months. Of 59 who entered study, 79.1% group sign disease, whereas corresponding figure nonadjuvant...
From 1970 to 1986, 304 patients underwent limb salvage resections for 271 malignant and 33 benign tumors of the extremities. Reconstruction was with a prosthesis or nonbiologic spacer. Nonmechanical complications were analyzed determine influence site method reconstruction use chemotherapy on their incidence severity. There 82 shoulder resections, 53 proximal femur 169 knee resections. No used in 115 patients; neoadjuvant therapy 128 adjuvant 61. 120 complications. The most common...
We reviewed the cases of nine patients with a giant-cell tumor vertebrae. All segments spine can be affected by tumor, but there was predilection for lumbar in our series. Pain present all patients. The maximum duration before diagnosis made three years and minimum, forty-five days (average, 12.2 months). In six neural deficit also present. One patient treated many ago radiation therapy alone; were decompressive laminectomy; two, excision lesion postoperative therapy; underwent lesional...
PURPOSE In the last few years, search for new biologic markers in high-grade non-Hodgkin's lymphomas has provided important results. particular, soluble CD30 (sCD30) levels were elevated most patients with Hodgkin's disease (HD) and anaplastic large-cell lymphoma (ALCL). PATIENTS AND METHODS From September 1988 to October 1993, treatment was completed 70 previously untreated ALCL, of whom 38 had common type (ALCL-CT) 32 Hodgkin's-like subtype (ALCL-HL). Serum sCD30 measured at time diagnosis...
The authors report on the results obtained in 30 consecutive cases of primary non-Hodgkin's lymphoma bone (PNHLB) treated at Istituto Ortopedico Rizzoli between 1972 and 1982. Four patients were with radiotherapy only 26 plus adjuvant chemotherapy. At a median follow-up 86 months (range, 30-160), among chemotherapy also there 3 relapses (2 had meningeal involvement 1 recurrence another bone). Relapse (local multiple new localizations) was observed one four only. These are compared 68 Ewing's...
Peripheral dedifferentiated chondrosarcoma (CS) is an exceedingly rare variant of the highly malignant entity chondrosarcoma. Only five such cases have previously been reported. Seven are analyzed and evaluated for presentation natural history this lesion when it arises in a tumor that was osteochondroma. Both peripheral central chondrosarcomas high-grade lesions require wide or radical surgical margins adequate treatment. Despite resection, survival poor; seven presented herein died...