A5019899657- Veterinary medicine and infectious diseases
- Animal Virus Infections Studies
- Microbial infections and disease research
- Pharmacological Effects of Natural Compounds
- Clostridium difficile and Clostridium perfringens research
- Streptococcal Infections and Treatments
- Veterinary Equine Medical Research
- Natural product bioactivities and synthesis
- Humic Substances and Bio-Organic Studies
- Viral gastroenteritis research and epidemiology
- Animal Nutrition and Physiology
- Animal Disease Management and Epidemiology
- Prion Diseases and Protein Misfolding
- Effects of Environmental Stressors on Livestock
- Tracheal and airway disorders
- Plant and fungal interactions
- Bacterial Identification and Susceptibility Testing
- Neurogenetic and Muscular Disorders Research
- Xenotransplantation and immune response
- Concrete and Cement Materials Research
- Skin and Cellular Biology Research
- Animal Behavior and Welfare Studies
- Microscopic Colitis
- Viral Infections and Immunology Research
- Autoimmune Bullous Skin Diseases
Scotland's Rural College
2015-2023
Scottish Agricultural Science Agency
1998-2020
The University of Queensland
2016
Scottish National Blood Transfusion Service
2005
Murdoch University
2004
University of Edinburgh
1950-2004
University Medical Center
2001
The Royal Free Hospital
2001
Freeman Hospital
2001
Harefield Hospital
2001
Antimicrobial resistance in Streptococcus suis, a global zoonotic pathogen of pigs, has been mostly studied only diseased animals using surveys that have not evaluated changes over time. We compared patterns between S. suis isolates from clinical cases disease (CC) and non-clinical case (NCC) pigs England, collected two discrete periods, 2009–2011 2013–2014. Minimum inhibitory concentrations (MIC) 17 antimicrobials (nine classes) were determined on 405 categorised by sampling period...
The usefulness of oral fluid (OF) sampling for surveillance infections in pig populations is already accepted but its value as a tool to support investigations porcine respiratory disease complex (PRDC) has been less well studied. This study set out describe detection patterns reproductive and syndrome virus (PRRSV), circovirus type 2 (PCV2), swine influenza A (SIV) Mycoplasma hyopneumoniae (M. hyo) among farms showing differing severity PRDC. included six wean-to-finish batches from with...
The plantar response is a reflex that involves not only the toes, but all muscles shorten leg. In newborn synergy brisk, involving flexor of leg; these include toe 9extensors9, which also leg on contraction and therefore are flexors in physiological sense. As nervous system matures pyramidal tract gains more control over spinal motoneurones flexion becomes less 9extensors9 no longer part it. toes then often go down instead up, as result segmental small foot overlying skin, comparable to...
A PCR system for the detection and identification of group IV spirochetes (Serpulina pilosicoli) was designed to complement biochemical tests, e.g., hippurate hydrolysis beta-glucosidase verify accuracy a previously proposed classification system. The assay based on amplification segment 16S rRNA gene. Both primers were constructed selectively amplify gene Serpulina pilosicoli. All analyzed strains exhibiting capacity hydrolyze lacking activity, including type strain spirochetal diarrhea,...
SUMMARY The prevalence of anti-HEV isotype-specific antibodies and viraemia were investigated in serum samples collected from slaughter-age pigs (aged 22–24 weeks) 23 farms Scotland. Of 176 tested, 29·0% ( n = 51) IgG positive, 36·9% 65) IgA positive IgM positive. Overall seroprevalence (anti-HEV IgG+ and/or IgA+ IgM+) was 61·4% 108). HEV RNA detected 72/162 (44·4%). Partial sequence ORF2 (98 nt) obtained eight RNA-positive phylogenetic analysis confirmed that they all genotype 3. This is...
Investigations into the possible causes of colitis and typhlocolitis were carried out on 85 pig units in United Kingdom between 1992 1996. Serpulina pilosicoli was identified most commonly, occurring as suggested primary agent 21 (25 per cent) but forming part mixed infections another 23 (27 units, main co‐infections being Yersinia pseudotuberculosis (eight units), proliferative enteropathy (six Salmonella species (four units) or hyodysenteriae (two units). ‘Atypical’ species, S ,...
Summary The effects of environmental control on horses affected with chronic obstructive pulmonary disease was assessed by clinical examination and function tests, ie, maximum change in intrathoracic pressure, tidal volume, minute non‐elastic work breathing, dynamic compliance, inspiratory expiratory flow rates arterial blood gas analysis. A controlled environment (ie, bedding shredded paper feeding a complete cubed diet) caused symptomatic COPD to become asymptomatic within four 24 days...
The aetiology, pathophysiological changes, pathology and clinical signs of the disease as presently understood are discussed. condition appears to be a hypersensitivity respiratory system in some horses poor quality hay straw. Micropolyspora faeni is chief agent identified northern part United Kingdom. In other locations, probably different. principal changes spasm airways bronchiolitis small airways. Onset may acute or insidious. well known but process reversible if source antigen removed....
When stabled in a controlled environment, horses effected with chronic obstructive pulmonary disease (COPD) became clinically asymptomatic 4 to 32 days (mean [+/-sd] 9.1 +/- 4.9 days), the time being influenced most by severity of judged on maximum intrathoracic pressure change (Max delta Ppl) and age animal. Sodium cromoglycate, drug widely used for prophylaxis allergic respiratory man, was administered inhalation 56 COPD-affected horses. The results showed that linear response existed...
To characterize the immune response associated with Lawsonia intracellularis infection, twenty-eight, 7-week-old pigs were dosed orally a pure culture of L. intracellularis. Animals killed 3, 7, 14, 21, 28, 35, and 42 days postinfection. Light microscopic studies undertaken to immunophenotype immunologic using specific antibodies T-cell subsets (CD3, CD4, CD8), B cells, major histocompatibility complex class II, cadherin, macrophages over course time. The results indicate that there is...
ABSTRACT Porcine dermatitis and nephropathy syndrome (PDNS) is a sporadic, usually fatal disease of growing finishing pigs that has been recognized in many pig-producing countries. Pasteurella multocida strains isolated from 15 with PDNS 51 without were characterized by capsule somatic antigen typing, random amplified polymorphic DNA (RAP-D) restriction analysis genomic using pulsed-field gel electrophoresis (PFGE). While capsular, somatic, RAP-D typing did not discriminate isolates non-PDNS...
This paper documents the salient clinical and pathological features of porcine dermatitis nephropathy syndrome (PDNS) in 96 pigs submitted from 55 units UK 1993 to 1998. series cases pre-dated emergence post-weaning multisystemic wasting (PMWS) UK. The morbidity during outbreaks was 1% or less. Affected ranged 14 70 kg weight most died after a short illness. Fifty-five had multifocal coalescing erythematous skin lesions, some progressing dermal necrosis. Biochemistry showed raised serum...
One hundred and forty Cheviot 100 Suffolk cross Mule primiparous 1-2-year-old ewes, from a flock of about 700 were vaccinated with an attenuated live 1B strain Chlamydia abortus vaccine 4 weeks before ram introduction (September 2011). Between 08 March 01 April 2012, 50 2-year-old ewes aborted 29 these died, despite antimicrobial anti-inflammatory treatment supportive care.Seven fetuses three placentae five submitted for pathological investigation. The showed stages autolysis ranging being...
Serpulina pilosicoli is an anaerobic spirochete which has been isolated from the colons of pigs with enteric disease. The clinical and pathologic features experimental infections conventional (born by normal farrowing a naturally acquired intestinal flora) three strains S. were determined in order to confirm enteropathogenicity this species. Strains derived British colitis passaged 8 10 times during expansion purification vitro. Eighteen ten-week-old Large White-Landrace cross each...
The therapy of equine chronic obstructive pulmonary disease (COPD) essentially entails minimising the horse's exposure to aetiological antigens which are predominantly thermophilic actinomycetes and moulds occurring in hay straw. This can be achieved, for example, by keeping affected horses permanently out doors, or when stabled, using shredded paper, wood shavings peat moss as bedding feeding a complete cubed diet. There should no supplementary apart from dust-free vacuum-packed hay....