A5013824835- Genetics, Aging, and Longevity in Model Organisms
- Circadian rhythm and melatonin
- Neurobiology and Insect Physiology Research
- Insect and Arachnid Ecology and Behavior
- Physiological and biochemical adaptations
- Evolution and Genetic Dynamics
- Evolutionary Game Theory and Cooperation
- Bat Biology and Ecology Studies
- Nematode management and characterization studies
- Molecular spectroscopy and chirality
- Spectroscopy and Quantum Chemical Studies
- Porphyrin and Phthalocyanine Chemistry
Max Planck Institute of Neurobiology
2024
Max Planck Institute for Neurobiology of Behavior – caesar
2023-2024
Osaka University
2014-2023
Life & Brain (Germany)
2023
Center of Advanced European Studies and Research
2021
The surface of an organism is a dynamic interface that continually adapts to its environment. In nematodes, the cuticle forms complex boundary protects against physicochemical pressures. However, precise molecular composition and function this remain largely unexplored. By utilizing 3D-OrbiSIMS, advanced surface-sensitive mass spectrometry method, we directly characterized outermost regions (∼50 nm) Caenorhabditis elegans Pristionchus pacificus improve understanding species-specific lipid...
Kin-recognition is observed across diverse species forming an important behavioral adaptation influencing organismal interactions. In many species, the molecular mechanisms involved are difficult to characterize, but in nematode Pristionchus pacificus components regulating its kin-recognition system have been identified. These determine predatory behaviors towards other con-specifics which prevents killing and cannibalization of kin. Importantly, their impact on interactions including...
Animal behavior is the final and integrated output of brain activity. Thus, recording analyzing critical to understand underlying function. While animal has become easier than ever with development compact inexpensive devices, detailed behavioral data analysis requires sufficient prior knowledge and/or high content such as video images postures, which makes it difficult for most be efficiently analyzed. Here, we report a versatile method using hybrid supervised/unsupervised machine learning...
Animals' sensory systems adjust their responsiveness to environmental stimuli that vary greatly in intensity. Here we report the neural mechanism of experience-dependent adjustment, especially gain control, ASH nociceptive neurons Caenorhabditis elegans. Using calcium imaging under gradual changes stimulus intensity, find naive animals respond concentration increases a repulsive odor 2-nonanone regardless magnitude increase. However, after preexposure odor, exhibit significantly weak...
ABSTRACT/SUMMARY Chemical signalling facilitates organismal communication and coordinates physiological behavioural processes. In nematodes, has predominantly focused on secreted molecules leaving the surface’s communicative potential unexplored. By utilising 3D-OrbiSIMS, an advanced surface-sensitive mass spectrometry method, we directly characterised molecular composition of outermost regions (50 nm in depth) Caenorhabditis elegans Pristionchus pacificus to improve understanding...
Behaviors are adaptive traits evolving through natural selection. Crucially, the genetic, molecular, and neural modifications that shape behavioral innovations poorly understood. Here, we identify specialized adaptations linked to evolution of aggression in predatory nematode Pristionchus pacificus . Using machine learning, identified robust states associated with aggressive episodes. These depend on invertebrate noradrenergic pathway, octopamine promoting bouts, tyramine antagonistically...
Abstract The J-aggregates of the diprotonated tetraphenylporphin formed in o/w microemulsions including 2-alkyl alcohol, Triton X-100, toluene, and sulfuric acid, exhibited an induced circular dichroism (ICD) spectra corresponding to chirality alcohol. ICD intensity remarkably depended on concentrations X-100 acid as well results suggested nonstoichiometric formation chiral conformation nano-J-aggregates microemulsion droplets.
Abstract Kin-recognition is observed across diverse species forming an important behavioral adaptation influencing organismal interactions. In most species, proximate level mechanisms are poorly characterized, but in the nematode Pristionchus pacificus molecular components regulating its kin-recognition system have been identified which determine predatory behaviors. This ability prevents killing of kin however, impact on other interactions including collective behaviors unknown. Utilizing...
ABSTRACT Animal behavior is the final and integrated output of brain activity. Thus, recording analyzing critical to understand underlying function. While animal has become easier than ever with development compact inexpensive devices, detailed behavioral data analysis requires sufficient previous knowledge and/or high content such as video images postures, which makes it difficult for most be efficiently analyzed Here, we report a versatile method using hybrid supervised/unsupervised...
ABSTRACT Animals’ sensory systems adjust their responsiveness to environmental stimuli that vary greatly in intensity. Here we report the neural mechanism of experience-dependent adjustment, especially gain control, ASH nociceptive neurons Caenorhabditis elegans . Using calcium imaging under gradual changes stimulus intensity, find naive animals respond concentration increases a repulsive odor 2-nonanone regardless magnitude increase. However, after preexposure odor, exhibit significantly...