A5103078830- Head and Neck Cancer Studies
- Renal cell carcinoma treatment
- COVID-19 and healthcare impacts
- Cancer Genomics and Diagnostics
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Immunotherapy and Biomarkers
- Renal and related cancers
- Nonmelanoma Skin Cancer Studies
- Palliative Care and End-of-Life Issues
- Oral health in cancer treatment
- Polyomavirus and related diseases
- Bladder and Urothelial Cancer Treatments
- Migraine and Headache Studies
- Cancer survivorship and care
- Vestibular and auditory disorders
- Economic and Financial Impacts of Cancer
- Ear and Head Tumors
- Voice and Speech Disorders
- Global Cancer Incidence and Screening
- Multiple and Secondary Primary Cancers
- Meningioma and schwannoma management
- Sympathectomy and Hyperhidrosis Treatments
- Cancer and Skin Lesions
- Ear Surgery and Otitis Media
Temple University
2023-2024
Temple University Hospital
2024
Medical University of South Carolina
2020-2021
The University of Texas Southwestern Medical Center
2018-2021
MUSC Hollings Cancer Center
2020
The University of Texas at Dallas
2018
Migraine is characterized by a collection of neurological symptoms in the absence injury or damage. However, several common preclinical migraine models require significant damage to skull stimulate dura mater, likely source afferent signaling leading head pain. The goal this study was determine whether dural stimulation can be performed mice using an injection that does not cause damage.Using mice, injections stimuli were administered mater through soft tissue at intersection between...
Importance For patients with head and neck squamous cell carcinoma (HNSCC), initiation of postoperative radiation therapy (PORT) within 6 weeks surgery is recommended by the National Comprehensive Cancer Network Guidelines Commission on Cancer. Although individual-level measures socioeconomic status are associated receipt timely, guideline-adherent PORT, role neighborhood-level disadvantage has not been examined. Objective To characterize association delays in receiving PORT. Design,...
645 Background: With the approval of immune-checkpoint inhibitors (ICI) as first and second line agents for treating metastatic renal cell carcinoma (RCC), immune-related adverse events (irAE) are a growing concern. In this study, we present safety profile outcomes 90 patients with RCC treated at two centers, including university (UT Southwestern/Clements University Hospital) county hospital Southwestern/Parkland). Methods: All ICI were identified from 2013 to January 31, 2018. We examined...
Abstract Background Cabozantinib is approved for metastatic renal cell carcinoma (mRCC) based on the METEOR and CABOSUN trials. However, real‐world effectiveness dosing patterns of cabozantinib are not well characterized. Methods Patients with mRCC treated between 2011 2019 were identified stratified using International Database Consortium (IMDC) risk groups. First‐ (1L), second‐ (2L), third‐ (3L), fourth‐line (4L) overall response rate (ORR), time to treatment failure (TTF), survival (OS)...
Abstract Background Greater auricular nerve (GAN) sacrifice can alter sensation; however, the impact on quality of life (QoL) is unclear. Objective The aim this study was to evaluate patients' QoL following GAN versus preservation. Methods Patients who underwent parotidectomy from 2010 2019 at a single institution completed two surveys. Results between GAN‐sacrificed preserved cohorts and short (≤ 1 year) long‐term (> follow‐up were compared. Of 404 patients, 67 with known status patients...
Abstract The COVID‐19 pandemic has had a significant impact on many aspects of head and neck cancer (HNC) care. uncertainty stress resulting from these changes led patients caregivers to turn HNC advocacy groups for guidance support. Here we outline some the issues being faced by with during current crisis provide examples programs developed address them. We also highlight increased utilization organizations that been observed as well challenges not‐for‐profit they work serve community.
<h3>Importance</h3> The American Joint Committee on Cancer staging system (<i>Cancer Staging Manual, 8th Edition</i>) for head and neck squamous cell carcinoma (HNSCC) now categorizes human papillomavirus (HPV)–negative HNSCC in a single positive lymph node smaller than 3 cm with pathologic extranodal extension (ENE) as N2a. standard of care ENE is adjuvant chemoradiation therapy (CRT). Whether adding chemotherapy concurrent radiation improves survival this clinical scenario unknown....
Objective Pathologic extranodal extension (ENE) is an important adverse feature for human papillomavirus (HPV)–negative head and neck squamous cell carcinoma (HNSCC), but the prognostic significance of microscopic ENE (ENE mi ) role adjuvant concurrent chemoradiation (CRT) remain unclear. This study evaluates (1) in HPV‐negative HNSCC (2) whether CRT associated with improved overall survival (OS) these patients. Study Design Retrospective cohort study. Setting Commission on Cancer...
584 Background: In mRCC, ipilimumab and nivolumab (ipi-nivo) is a 1L treatment option. Recent data have also shown efficacy of PD(L)1-VEGF (PV) inhibitor combinations. The these two strategies has not been compared. Methods: Using the IMDC dataset, patients (pts) treated with any PV combination were compared to those ipi-nivo. Multivariable Cox regression analysis was performed control for imbalances in risk factors. Results: 164 pts received IO therapy: 104 combinations 60 Baseline...