A5088190699- COVID-19 Clinical Research Studies
- Respiratory viral infections research
- Cancer-related molecular mechanisms research
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Inflammasome and immune disorders
- SARS-CoV-2 detection and testing
- Hepatitis C virus research
- MicroRNA in disease regulation
- COVID-19 and healthcare impacts
- RNA modifications and cancer
- Circular RNAs in diseases
- Viral gastroenteritis research and epidemiology
- Liver Disease Diagnosis and Treatment
- Lipid metabolism and disorders
- RNA regulation and disease
- Liver Diseases and Immunity
Ain Shams University
2020-2024
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection provides a critical host-immunological challenge. Aim: We explore the effect of host-genetic variation in interferon-lambda-3 rs12979860, Tolloid Like–1 (TLL1) rs17047200 and Discoidin domain receptor 1(DDR1) rs4618569 on host response to viral infections disease severity that may probe mechanistic approach allelic virus-induced inflammatory responses. Methods: 141 COVID-19 positive patients 100 healthy...
Acute coronary syndrome (ACS) is a major cause of death all over the world. STEMI represents type myocardial infarction with acute ST elevation. We aimed to assess predictive power potential RNA panel expression in syndrome.We used silico data analysis retrieve RNAs related glycerophospholipid metabolism dysregulation and specific ACS that results selection Alpha/Beta hydrolase fold domain4 (ABHD4) mRNA its epigenetic regulators (Foxf1 adjacent noncoding developmental regulatory (FENDRR)...
(1) Background: The coronavirus (COVID-19) pandemic is still a major global health problem, despite the development of several vaccines and diagnostic assays. Moreover, broad symptoms, from none to severe pneumonia, various responses assays, make infection control challenging. Therefore, there an urgent need develop non-invasive biomarkers quickly determine severity. Circulating RNAs have been proven be potential for variety diseases, including infectious ones. This study aimed genetic...
Abstract Subject Area: SARS-CoV-2 Purpose: COVID-19 is the most recent pandemic causing morbidity and mortality. Although a part of pathogens SARI, it unique in pulmonary thrombosis lung fibrosis. Thus different management needed. We aimed o explore start preserved SARI samples to know exact time its emergence our hospital, conduct whole-genome sequencing positive define strain. To assess clinical characteristics severe respiratory infection admitted El-Demerdash hospitals that same period...
The SARS-CoV-2 pandemic has led to over 4.9 million deaths as of October 2021. One the main challenges creating vaccines, treatment, or diagnostic tools for virus is its mutations and emerging variants. A couple variants were declared more virulent infectious than others. Some approaches used nomenclature lineages. most Pangolin nomenclature. In our study, we enrolled 35 confirmed patients sequenced viral RNA in their samples. We also aimed highlight hallmark frequent lineage. identified a...
Abstract Aim: to know the start of COVID-19 in Ain shams University hospitals (El-Demerdash) Severe acute respiratory illness.Materials and methods: retrospective collection data records previously collected nasopharyngeal oropharyngeal sample stored our lab for determining hospitals, using RT-PCR postive samples we will conduct Sequencing analysis photogenic analysis. Also epidemiological study negatively screened patients, determine most common causes SARI mortality this category patients
Abstract Purpose: COVID-19 is the most recent pandemic causing morbidity and mortality. Although a part of pathogens SARI, it unique in pulmonary thrombosis lung fibrosis. Thus different management needed. We aimed o explore start SARS-CoV-2 preserved SARI samples to know exact time its emergence our hospital, conduct whole-genome sequencing positive define strain. To assess clinical characteristics severe respiratory infection admitted El-Demerdash hospitals that same period from own file...