- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Hip and Femur Fractures
- Bone health and osteoporosis research
- Orthopedic Surgery and Rehabilitation
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Shoulder Injury and Treatment
- Pelvic and Acetabular Injuries
- Spine and Intervertebral Disc Pathology
- Lower Extremity Biomechanics and Pathologies
- Bone and Joint Diseases
- Spinal Fractures and Fixation Techniques
- Foot and Ankle Surgery
- Elbow and Forearm Trauma Treatment
- Medical Practices and Rehabilitation
- Tendon Structure and Treatment
- Musculoskeletal Disorders and Rehabilitation
- Bone Tissue Engineering Materials
- Musculoskeletal pain and rehabilitation
- Knee injuries and reconstruction techniques
- Bone Metabolism and Diseases
- Bone health and treatments
- Shoulder and Clavicle Injuries
Berufsgenossenschaftliche Unfallklinik Murnau
2016-2025
Paracelsus Medical University
2016-2025
Paracelsus Medizinische Privatuniversität
2011-2023
Biomechanics Institute of Valencia
2019
Stryker (United States)
2009-2018
Arthrex (United States)
2018
Denver Health Medical Center
2018
University of Colorado Denver
2018
University of Salzburg
2012-2017
Legacy Health
2016
An interdisciplinary study based on animal experiments, cell culture studies, and finite element models is presented. In a sheep model, the influence of osteotomy gap size interfragmentary motion healing success was investigated. Increasing sizes delayed process. movement stimulated callus formation but not tissue quality. Typical distributions intramembranous bone, endochondral ossification, connective in fracture are quantified. The comparison mechanical data determined by model with...
Abstract Flexible fixation of fractures with minimally invasive surgical techniques has become increasingly popular. Such can lead to relatively large fracture gaps (larger than 5 mm) and considerable interfragmentary movements (0.2‐5 mm). We investigated the influence size gap, movement, strain on quality healing. A simple diaphyseal long‐bone was modeled by means a transverse osteotomy right metatarsus in sheep. In 42 Sheep, stabilized custom‐made external ring fixator that adjustable for...
This study tested the hypothesis that interfragmentary axial movement of transverse diaphyseal osteotomies would result in improved fracture healing compared to shear movement. Ten skeletally mature merino sheep underwent a middiaphyseal osteotomy right tibia, stabilized by external fixation with an gap 3 mm. A custom made fixator allowed either pure (n=5) or 1.5 mm amplitude during locomotion animals. The was monitored weekly two extensometer temporarily attached fixator. After 8 weeks were...
Quantitative bone assessment today is primarily based on the analysis of mineral density (BMD). The geometric properties bone, which are an important parameter for skeletal strength, generally not considered in routine clinical osteoporosis. This study combined and BMD values determined by peripheral quantitative computed tomography (pQCT) at distal radius femoral neck to predict fracture loads radius, femur, lumbar vertebrae 20 cadavers. Generalized osteopenia reduced all three sites (p <...
Abstract The purpose of this study was to use high resolution (HR) magnetic resonance (MR) images the calcaneus investigate trabecular structure patients with and without osteoporotic hip fractures compare these techniques bone mineral density (BMD) in differentiating fracture nonfracture patients. Axial sagittal HR MR were obtained 50 females (23 postmenopausal 27 controls). A three-dimensional gradient–echo sequence used a slice thickness 500 μm plane 195 × μm. Texture analysis performed...
To investigate the influence of stability an osteotomy fixation on local vascularization and tissue differentiation in callus healing, a transverse right metatarsal with gap size 2 mm was performed 10 sheep stabilized external fixator. This fixator permitted defined axial movement. Two groups 5 were each operated upon to allow 0.2 (group A) or 1 B) Nine weeks after surgery, dissected histological sections prepared. The type vessel distribution determined. Larger interfragmentary movements...
Locked bridge plating relies on secondary bone healing, which requires interfragmentary motion for callus formation. This study evaluated healing of fractures stabilized with a locked construct and far cortical locking construct, is modified approach that promotes motion. The tested whether constructs can improve fracture-healing compared standard constructs.In an established ovine tibial osteotomy model 3-mm gap size, twelve osteotomies were randomly or applied medially. designed to provide...
Abstract To characterize the site‐specific mechanical and histological properties in fracture repair to relate these initial situation, an experimental model was used metatarsus of 42 sheep. situation a transverse osteotomy described by three gap sizes (1,2, or 6 mm) two amounts strain (7 31 %). An external fixator that allowed defined axial movement provided control settings. Nine weeks following surgery, healing area dissected tensile compressive were measured subregions periosteal callus....
Bottlang, Michael PhD; Doornink, Josef MS; Lujan, Trevor J. Fitzpatrick, Daniel C. MD; Marsh, Lawrence Augat, Peter von Rechenberg, Brigitte DVM, ECVS; Lesser, Maren DVM; Madey, Steven M. MD Author Information