A5017715793- Peripheral Artery Disease Management
- Cardiovascular Disease and Adiposity
- Adipokines, Inflammation, and Metabolic Diseases
- IL-33, ST2, and ILC Pathways
- Sleep and Wakefulness Research
- Sleep and related disorders
- Systemic Sclerosis and Related Diseases
- Regulation of Appetite and Obesity
- Cardiovascular Health and Disease Prevention
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Atherosclerosis and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Circadian rhythm and melatonin
- Obstructive Sleep Apnea Research
- Computational Drug Discovery Methods
- Cardiac Valve Diseases and Treatments
- Cardiac Fibrosis and Remodeling
- Neuroscience of respiration and sleep
- Antiplatelet Therapy and Cardiovascular Diseases
- Gallbladder and Bile Duct Disorders
- Healthcare, Law, Governance, and Management Studies
- Vascular Procedures and Complications
Clinical Emergency Hospital Bucharest
2023-2025
Iuliu Hațieganu University of Medicine and Pharmacy
2014-2025
County Hospital
2015-2018
Spitalul Clinic Județean de Urgență Cluj-Napoca
2018
University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca
2015
University of Florida Health Science Center
1995
Background/Objectives: The COVID-19 pandemic underscored the need for adaptive public health strategies and effective decision-making tools to optimize clinical responses policy measures based on regional contexts. This study aims identify key criteria developing a patient-centered strategy enhance resilience of Romania’s healthcare system during pandemic. Methods: research introduces Multi-Criteria Decision Analysis (MCDA) model using Simple Multiple Attribute Assessment Technique (SMART)...
Background . Echocardiographic evaluation of left ventricular (LV) structural and functional alterations in hypertension has some limitations, potentially overcome by using biomarkers. ST2, a prognostic biomarker for heart failure myocardial infarction patients, was less studied hypertension. Aim To analyze the relationship between serum ST2 levels diastolic dysfunction (DD) Method We enrolled 88 hypertensive outpatients (average age 65 years, 69.3% females) prospective study, stratified...
The involvement of leptin in atherosclerosis is very complex, including inflammation, the oxidative stress and thrombosis. Leptin has atherogenic also antiatherogenic actions. In obesity elevated levels are not sufficient to prevent disturbances energy balance, suggesting that obese people resistant. aim study was investigate relationship between baseline plasma incidence new ischemic events patients with CHD.Plasma fifty nine consecutive (29 men 30 women) CHD hospitalized County Emergency...
Basal cell carcinoma (BCC) is a malignant skin cancer which commonly exhibits aberrant blood flow because of angiogenesis. Its invasiveness and lack metastatic potential may be explained by the typical pattern vascularization seen in BCCs, where vessels are absent tumor islands prominent tumor's periphery. From clinical point view, high-frequency ultrasound (HFUS) useful tool for evaluation lateral depth extension these tumors; furthermore, employing color Doppler, important data regarding...
The progression of heart failure is the result interaction several pathogenetic processes that involve activation biomarkers belonging to renin angiotensin aldosterone system (RAAS), its counterregulatory mechanisms, sympathetic nervous and inflammation, oxidative stress. This study aimed at determining prognostic role in evolution patients with failure. These are representative different pathways involved possible interrelationships between them remodelling. Method. a progressive...
Background . sST2 represents a useful biomarker for the diagnosis and prognosis of patients with heart failure, but limited data is available on its role in hypertension. The aim this study to evaluate short-term value an unfavorable outcome hypertensive patients. Methods This was prospective observational which enrolled 80 hypertension, who were followed one year. All underwent clinical, laboratory (including sST2), echocardiographic assessment at baseline. grouped according cardiovascular...
The degenerative aortic stenosis (AS) is the most frequent valvular disease in elderly (over 75 years), and its severe form found 12.4% associated with a low survival rate at 5 years (15-50%).These patients are categorised as frail only possible choice of treatment transcatheter valve implantation (TAVI).When cardiac rehabilitation programs (CRP) were introduced after TAVI, they had positive impact on clinical outcome, increasing quality life decreasing morbidity mortality, especially high...
Despite efforts at treatment, obstructive sleep apnea (OSA) remains a major health problem, especially with increasing evidence showing an association cardiovascular morbidity and mortality. The treatment of choice for OSA patients is Continuous Positive Airway Pressure (CPAP), which has been proven in randomized controlled trials to be effective therapy this condition. impact CPAP on the pathology associated remains, however, unclear. Although effect previously studied relation outcome,...
Background: A number of cytokines and adipokines secreted by adipose tissue may influence vessel wall directly. Adiponectin exhibits anti-inflammatory atheroprotective actions. Resistin is expressed at higher levels in inflammatory cells. directly activates the endothelium through upreglation adhesion molecules, induces production TNF-α macrophages, effects that are antagonized adiponectin. Leptin has multiple on cells artery walls, many similar to those resistin. The prognostic role...
Heart failure is a significant healthcare problem, because of its impact at the individual and populational level, through multiple rehospitalizations increased morbi-mortality.At multidimensional this clinical condition treatment on patients' daily lives reflected in quality life (QoL).QoL needs to be accurately measured, it's related high hospitalization mortality rates provides valuable information that cannot directly obtained using clinical, biological or imaging measurements.For these...
Introduction: Achieving restorative sleep is crucial for overall well-being, yet difficulties affect a substantial portion of the adult population. Sleep disturbances are associated with diminished quality life, physical complaints, cognitive impairment, and emotional regulation challenges. Objective: This study explores influence an innovative experimental bed designed to generate rocking motions on parameters. Methods: A prospective observational enrolled 60 participants, assessing their...
Background/Objectives: Some specific types of white blood cells (WBCs) and the neutrophil/lymphocyte ratio (NLR) are independent predictors outcome for heart failure (HF) patients. WBC redistribution is induced by catecholamines, therefore we evaluate how different beta-blockers (BBs) influence it. Methods: The HF patients were clinically evaluated, was drawn to measure N-Terminal pro–B-type natriuretic peptide (NT-proBNP), WBC-differential formula, etc. Results: On admission, 61.16% who...
While the number of clinical experiments investigating effects non-steroid antiinflammatory drugs (NSAIDs) on cardiovascular (CV) events has significantly increased over last two decades, basic research related to mechanism by which NSAIDs cause CV dysfunction is limited.High variability in trials conducted (different populations, dosages, exposure and types NSAIDs) led results are difficult interpret compare between studies.Are there some safer than other from standpoint risk?We have try...
The prevalence of cardiovascular disease (CVD) in chronic inflammatory rheumatic diseases (CIRD) is higher than the general population.This results from compound effect traditional (CV) risk factors (CVRF) along with inflammation and genetic components.But, most patients increased CV events had a moderate risk.Despite recent advances management diseases, CVD remains high subjects CIRD who are followed up periodically at outpatient rheumatology clinics.Classic CVRF duration associated an CVD.