A5087871575- Coral and Marine Ecosystems Studies
- Marine Invertebrate Physiology and Ecology
- Aquaculture disease management and microbiota
- Plant Pathogens and Resistance
- Vibrio bacteria research studies
- Biosensors and Analytical Detection
- Marine Sponges and Natural Products
- Protist diversity and phylogeny
- Marine Toxins and Detection Methods
- Marine Ecology and Invasive Species
- Web Applications and Data Management
- Immune Response and Inflammation
- Higher Education Research Studies
- Aquaculture Nutrition and Growth
- Diverse Educational Innovations Studies
- Antimicrobial Peptides and Activities
- Human Health and Disease
- Coastal wetland ecosystem dynamics
- Innovative Teaching Methods
- Genetics, Bioinformatics, and Biomedical Research
- Parasite Biology and Host Interactions
- Fish biology, ecology, and behavior
- Marine Biology and Ecology Research
- Plant Pathogenic Bacteria Studies
- Sphingolipid Metabolism and Signaling
Berry College
2017-2024
Oregon State University
2012-2018
Western Oregon University
2015-2017
Poole Hospital
2017
The complement system is an innate immune pathway that in vertebrates, responsible for initial recognition and ultimately phagocytosis destruction of microbes. Several molecules including C3, Factor B, mannose binding lectin associated serine proteases (MASP) have been characterized invertebrates while most studies focused on their conserved role defense against pathogens, little known about managing beneficial purpose this study was to (1) characterize genes the symbiotic sea anemone A....
Many nonmodel species exemplify important biological questions but lack the sequence resources required to study genes and genomic regions underlying traits of interest. Reef-building corals are famously sensitive rising seawater temperatures, motivating ongoing research into their stress responses long-term prospects in a changing climate. A comprehensive understanding these processes will require extending beyond sequenced coral genome (Acropora digitifera) encompass diverse related...
Many cnidarians engage in a mutualism with endosymbiotic photosynthetic dinoflagellates that forms the basis of coral reef ecosystem. Interpartner interaction and regulation includes involvement host innate immune system. Basal metazoans, including have diverse complex repertoires are just beginning to be described. Scavenger receptors (SR) superfamily immunity genes recognize broad array microbial ligands participate phagocytosis invading microbes. The subclades named SR-A through SR-I...
The mutualistic endosymbiosis between cnidarians and dinoflagellates is mediated by complex inter-partner signaling events, where the host cnidarian innate immune system plays a crucial role in recognition regulation of symbionts. To date, little known about diversity thrombospondin-type-1 repeat (TSR) domain proteins basal metazoans or their potential cnidarian-dinoflagellate mutualisms. We reveal large diverse repertoire TSR seven anthozoan species, show that model sea anemone Aiptasia...
In host-microbe interactions, signaling lipids function in interpartner communication during both the establishment and maintenance of associations. Previous evidence suggests that sphingolipids play a role mutualistic cnidarian-Symbiodinium symbiosis. Exogenously applied have been shown to alter this partnership, though endogenous host regulation by sphingosine rheostat under different symbiotic conditions has not characterized. The regulates levels pro-survival sphingosine-1-phosphate...
Molecular stress responses associated with coral diseases represent an under-studied area of cnidarian transcriptome investigations. Caribbean Yellow Band Disease (CYBD) is considered a disease Symbiodinium within the tissues host Orbicella faveolata . There paucity diagnostic tools to assist in early detection and characterization diseases. The validity test determined by its ability distinguish organisms that have from those do not. detect identify disease-affected tissue before visible...
Abstract Microbes can initiate developmental gene regulatory cascades in animals. The molecular mechanisms underlying microbe-induced animal development and the evolutionary steps to integrate microbial signals into programs remain poorly understood. In upside-down jellyfish Cassiopea xamachana , a dinoflagellate endosymbiont initiates life stage transition from sessile polyp sexual medusa. We found that metabolic products derived symbiont carotenoids may be important C. development,...
GTPases of Immunity-Associated Proteins (GIMAP) are a group small GTP-binding proteins found in variety organisms, including vertebrates, invertebrates, and plants. These characterized by the highly conserved AIG1 domain, have been implicated regulation immune system as well apoptosis autophagy, though their exact mechanism action remains unclear. Recent work on cnidarian GIMAPs suggests role immunity, apoptosis, autophagy-three processes involved coral bleaching, or breakdown...
Coral reefs, one of the world's most productive and diverse ecosystems, are currently threatened by a variety stressors that result in increased prevalence both bleaching disease. Therefore, understanding molecular mechanisms involved these responses is critical to mitigate future damage reefs. One group genes potentially cnidarian immunity symbiosis GTPases Immunity Associated Proteins (GIMAP). In vertebrates, this family proteins regulating fate developing lymphocytes interacts with...
Abstract Guanosine Triphosphate (GTP)ases of Immunity Associated Proteins (GIMAP) are small G proteins that in vertebrates, regulate immunity, apoptosis, and autophagy. While previously thought to be limited vertebrates plants, this family was recently characterized a diversity dinoflagellates. However, information regarding the function GIMAPs dinoflagellates is lacking. Therefore, goal study (conducted from March-November 2022) assess expression cnidarian symbiont Breviolum minutum...
Complex biological concepts (like symbiosis and coral biology) that span multiple scales cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent teaching learning process of science, especially at undergraduate level. To address these issues, we developed Symbiotic <em>Exaiptasia</em>-Algae System, or SEA which leverages model anemone <em>Exaiptasia diaphana</em> (often used as a proxy corals in research...