- Cleft Lip and Palate Research
- Reconstructive Surgery and Microvascular Techniques
- Bone fractures and treatments
- Facial Nerve Paralysis Treatment and Research
- Surgical site infection prevention
- Craniofacial Disorders and Treatments
- Dermatologic Treatments and Research
- Body Contouring and Surgery
- Facial Rejuvenation and Surgery Techniques
- Orthopedic Infections and Treatments
- Laser Applications in Dentistry and Medicine
- Reconstructive Facial Surgery Techniques
- Surgical Sutures and Adhesives
- Breast Implant and Reconstruction
- Mesenchymal stem cell research
- Pelvic and Acetabular Injuries
- Bariatric Surgery and Outcomes
- Orthopedic Surgery and Rehabilitation
- Wound Healing and Treatments
- Facial Trauma and Fracture Management
- Vascular Procedures and Complications
- Tissue Engineering and Regenerative Medicine
- Immune Response and Inflammation
- Face recognition and analysis
- Traumatic Ocular and Foreign Body Injuries
Weill Cornell Medical College in Qatar
2018-2025
Great Ormond Street Hospital for Children NHS Foundation Trust
2025
Sidra Medical and Research Center
2020-2024
Mitchell Institute
2024
Texas A&M University
2024
Cornell University
2020-2022
Qatar Airways (Qatar)
2019-2022
Qatar Foundation
2019-2020
University College London
2013-2019
Great Ormond Street Hospital
2015-2019
With an aging population, skeletal fractures are increasing in incidence, including the typical closed and less common open normal bone, as well fragility patients with osteoporosis. For older age group, there is urgent unmet need to induce predictable bone formation improve implant fixation situations such hip joint replacement. Using a murine model of slow-healing fractures, we have previously shown that coverage fracture muscle accelerated healing increased union strength. Here, show...
Abstract The mechanism by which trauma initiates healing remains unclear. Precise understanding of these events may define interventions for accelerating that could be translated to the clinical arena. We previously reported addition low‐dose recombinant human TNF (rh ) at fracture site augmented repair in a murine tibial model. Here, we show local rh treatment is only effective when administered within 24 h injury, neutrophils are major inflammatory cell infiltrate. Systemic administration...
Background: Spring-assisted cranioplasty has been proposed as an alternative to total calvarial remodeling for sagittal craniosynostosis. Advantages include its minimally invasive nature, and reduced morbidity hospital stay. Potential drawbacks the need a second procedure removal lack of published long-term follow-up. The authors present single-institution experience 100 consecutive cases using novel spring design. Methods: All patients treated at authors’ institution between April 2010...
Social interactions are largely dependent on the interpretation of information conveyed through facial expressions. Although reanimation seeks restoration expression emotion, outcome measures have not addressed this directly. This study evaluates use a machine learning technology to directly measure before and after surgery. Fifteen subjects with palsy were evaluated both undergoing cross-facial nerve grafting free gracilis muscle transfer. Eight healthy volunteers assessed for control...
Mutations in the ERF gene, coding for ETS2 repressor factor, a member of ETS family transcription factors cause recently recognized syndromic form craniosynostosis (CRS4) with facial dysmorphism, Chiari‐1 malformation, speech and language delay, learning difficulties and/or behavioral problems. The overall prevalence mutations patients is around 2%, 0.7% clinically nonsyndromic craniosynostosis. Here, we present findings from 16 unrelated probands ERF‐related craniosynostosis, additional...
Background: Reconstruction following pharyngolaryngectomy presents a complex reconstructive challenge, and single-stage, reliable reconstruction allowing prompt discharge from the hospital return of swallowing speech function is required. The authors present their 10-year experience 43 jejunal free flaps for by single team outline operative algorithm to minimize postoperative morbidity. Methods: data patients who underwent flap circumferential pharyngoesophageal defects between March 2000...
Training a machine learning system to evaluate any type of facial deformity is impeded by the scarcity large datasets high-quality, ethics board-approved patient images. We have built deep learning-based cleft lip generator called CleftGAN designed produce an almost unlimited number high-fidelity facsimiles images with wide variation. A transfer protocol testing different versions StyleGAN as base model was undertaken. Data augmentation maneuvers permitted input merely 514 frontal...
Abstract Background Non-thermal light energy has been used to enhance wound healing. This is known as photobiomodulation (PBM). While preclinical evidence largely based on laser light, light-emitting diodes (LEDs) form the mainstay of clinical studies owing lack available lasers for non-clinical use. However, it speculated two technologies exhibit dissimilar biological responses. Objectives The influence a new, commercially near-infrared device gene expression profile human skin relative an...
Clinical obesity is characterized by excessive fat accumulation and an increased risk of numerous associated comorbidities. Adipose tissue secretes leptin other adipokines, which play key roles in regulating energy balance, glucose homeostasis, body mass. Recently, incretin pancreatic hormones have also been shown to influence these processes. However, the regulatory mechanisms interactions among are not yet fully understood. This study investigates hormonal predictors lean phenotype (in...
Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and heightened risk of comorbidities. This study aimed identify hormonal predictors an insulin-sensitive phenotype (ISP) in patients undergoing body contouring surgeries, focusing on the relationship between gut hormones, adipokines, mass. ISP was defined as highest tertile HOMA sensitivity. We prospectively followed abdominoplasty, lower lift, or thigh lift at Hamad General Hospital...