A5041185360- Drug-Induced Adverse Reactions
- Urticaria and Related Conditions
- Mast cells and histamine
- Pharmacovigilance and Adverse Drug Reactions
- Autoimmune Bullous Skin Diseases
- Adrenal Hormones and Disorders
- Asthma and respiratory diseases
- Safety Warnings and Signage
- Contact Dermatitis and Allergies
- Allergic Rhinitis and Sensitization
- Respiratory and Cough-Related Research
- Food Allergy and Anaphylaxis Research
- Immune Cell Function and Interaction
- Psychology and Mental Health
Universidade do Estado do Rio de Janeiro
2015-2024
Hospital Universitário Pedro Ernesto
2024
Betalactams are the most frequent cause of hypersensitivity reactions to drugs mediated by a specific immune mechanism. Immediate occur within 1 6 hours after betalactam administration, and generally IgE-mediated. They clinically translate into urticaria, angioedema anaphylaxis. Non-immediate or delayed hour administration. These common usually T cells. The type is maculopapular morbilliform exanthematous eruption. Most individuals who report allergies [...]
Background. Severe cutaneous adverse reactions (SCAR) are potentially fatal reactions. Genetic predisposition is involved in their pathogenesis related to drugs and ethnicities, however a mixed population these relationships still unknown. The aim of this study was describe phenotypes, suspect HLA-alleles SCAR, identified by systematized approach Brazilian case series. Methods. Patients who were diagnosed with SCAR between March 2011 July 2019 at our university hospital included. European...
Objective.Describing routine procedures, clinical profile and evolution of patients treated in a chronic urticaria (CU) reference center university hospital.Methods.Retrospective analysis records database CU registered between March 2011 February 2016 center.Besides demographic characteristics, disease duration, comorbidities, angioedema, thyroid lab tests, subtypes, provocation UAS CUQ2oL scores were recorded.Patients with 3 or more visits included regarding the first last visits, to...
This article was originally published online on 8 April 2015 Chronic urticaria (CU) is a debilitating disease that affects patients' quality of life (QoL) and the only questionnaire developed specifically to CU Urticaria Quality Life Questionnaire (CU-Q2oL). The aim this study evaluate QoL patients with correlate it activity. Brazilian Portuguese version CU-Q2oL self-administered in 96 adults treated at outpatient clinic university hospital. Disease activity assessed using Activity Score...
Beta-lactam (BL) allergy is considered a public health issue worldwide. To date, there no consistent data on the direct Oral Provocation Test (OPT) for BL in Brazilian children and adolescents. This study's main objective to describe safety profile of TPO this population.
This article was originally published online on 8 April 2015 Severe cutaneous allergic reactions (SCAR) have a wide range of severity and clinical manifestations. Some risk alleles are known in specific populations. The aim the study to describe laboratory profile patients with SCAR, treated at university hospital Rio de Janeiro. is retrospective cross-sectional study. Clinical data, including HLA typing, SCAR identified between March/2011 July/2014 by pharmacologic surveillance, weekly done...
This article was originally published online on 8 April 2015 There are different classification systems for allergic rhinitis (AR) severity, whose used to guide treatment. Clinical observation suggests that ARIA method, made by doctors, and visual analogic scale of symptoms (VASS), patients, do not obtain the same results in many occasions. The aim this study compare these methods applied at time a cohort adolescents adults with AR under specialized outpatient care. Retrospective clinical...