A5055518874- Viral Infections and Outbreaks Research
- Disaster Response and Management
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Global Security and Public Health
- Viral Infections and Vectors
- Adolescent Sexual and Reproductive Health
- Brucella: diagnosis, epidemiology, treatment
- HIV/AIDS Impact and Responses
- Growth Hormone and Insulin-like Growth Factors
- HIV/AIDS drug development and treatment
- Resilience and Mental Health
- Cancer Cells and Metastasis
- HIV-related health complications and treatments
- Digestive system and related health
- Poverty, Education, and Child Welfare
- Salmonella and Campylobacter epidemiology
- Animal Diversity and Health Studies
- Leptospirosis research and findings
- Viral gastroenteritis research and epidemiology
- Zoonotic diseases and public health
EcoHealth Alliance
2024-2025
University of North Carolina at Chapel Hill
2019-2023
University of Liberia
2020
Infectious Disease Research Institute
2019
Pennsylvania State University
2006
In July 2022, Ghana reported its first outbreak of Marburg virus disease (MVD). The source the was unknown. August 2022 we conducted a behavioral risk assessment, surveying 715 participants in three rural communities associated with presumptive index case: Site 1 Ashanti Region and Sites 2 3 Western Ghana. Our primary aim to characterize exposure wild domestic animals, specifically Egyptian rousette bats (ERBs), natural reservoir for virus. We focused on two routes potential ERBs: 1) eating...
Abstract Background Lingering symptoms have been reported by survivors of Ebola virus disease (EVD). There are few data describing the persistence and severity these over time. Methods Symptoms headache, fatigue, joint pain, muscle hearing loss, visual numbness hands or feet were longitudinally assessed among participants in Liberian Survivors Cohort study. Generalized linear mixed effects models, adjusted for sex age, used to calculate odds reporting a symptom it being rated as highly...
Background Lassa fever (LF), a haemorrhagic illness caused by the virus (LASV), is endemic in West Africa and causes 5000 fatalities every year. The true prevalence incidence rates of LF are unknown as infections often asymptomatic, clinical presentations varied, surveillance systems not robust. aim Enable research programme to estimate incidences LASV infection disease five African countries. core protocol described here harmonises key study components, such eligibility criteria, case...
Leptospirosis, caused by Leptospira spp., affects humans and animals, posing significant health economic burdens. This multidisciplinary One Health study aimed to estimate the prevalence of spp.-specific antibodies in livestock at human-animal interfaces Jordan. Study sites were selected across Jordan based on previous research showing a high likelihood zoonotic pathogen circulation. The population comprised 500 individuals 400 (sheep, goats, cattle, camels). Blood samples collected from...
Postnatal development of the mammary gland requires interactions between epithelial and stromal compartments, which regulate actions hormones growth factors. IGF-I is expressed in both compartments during postnatal gland. However, little known about how local expression epithelium or stroma regulates differentiation puberty pregnancy-induced alveolar development. The goal this study was to investigate mechanisms test hypothesis that has distinct functions. We established mouse lines with...
Cohort studies have reported a high prevalence of musculoskeletal, neurologic, auditory, and visual complications among Ebola virus disease (EVD) survivors. However, little is known about the host- disease-related predictors these symptoms their etiological mechanisms.The presence patterns 8 cardinal that are most commonly following EVD survival were assessed in 326 survivors who participated ongoing longitudinal Liberian Survivor Study. At quarterly study visits, developed since acute...
Despite its endemic status in the Middle East, key knowledge gaps persist regarding prevalence, transmission rate, and geographical distribution of both human livestock brucellosis Jordan. This study aimed to investigate seroprevalence as well incidence humans A total 500 participants (202 exposed 296 unexposed livestock) were enrolled study. Sampling was conducted at baseline 1.5 years later. Additionally, a 700 sampled, comprising 20 animals per taxa (camels, cattle, sheep, goats) site, (
Sexual transmission of Ebola virus (EBOV) is well established and has been implicated in multiple resurgences during the West African epidemic. Given persistence viral RNA semen, guidelines from World Health Organization (WHO) recommend abstinence or condom use for at least 1 year until two semen PCR tests are negative. To better understand impact testing on sexual behavior, male EVD survivors were surveyed regarding their behavior before after testing. Of 171 men who enrolled, 148 reported...
Interrupted time-series analyses, using 5 years of routinely collected health information system data, were conducted to estimate the magnitude impact 2014-2015 Ebola virus disease (EVD) epidemic and determine trends in tuberculosis (TB) care services Liberia. A segmented linear regression model was used generate estimates predictions for three TB service indicators before, during, after EVD, from January 2013 December 2017. It found that number presumptive cases declined significantly at...
Background Antiretroviral therapy (ART) is a lifesaving intervention for people living with HIV infection, reducing morbidity and mortality; it likewise essential to transmission. The “Treat all” strategy recommended by the World Health Organization has dramatically increased ART eligibility improved access. However, retaining patients on been major challenge many national programs in low- middle-income settings, despite actionable local policies ambitious targets. To estimate retention of...
Abstract Background Sexual transmission of the Ebola virus (EBOV) from male survivors to their partners has been well-documented. While studies have characterized sexual behaviors Virus Disease (EVD), there is little focus on intimate partners. This study seeks describe attitudes and women who had condomless sex with 2014-16 outbreak in Liberia, West Africa. Methods Participants were recruited through voluntary referral by partners, all whom participants a longitudinal EVD survivor cohort....