- Pregnancy and Medication Impact
- Neonatal Respiratory Health Research
- Assisted Reproductive Technology and Twin Pregnancy
- Academic Research in Diverse Fields
- Pregnancy and preeclampsia studies
- Reproductive Health and Contraception
- Renal function and acid-base balance
- Asthma and respiratory diseases
- Iron Metabolism and Disorders
- Preterm Birth and Chorioamnionitis
- Healthcare Regulation
- Birth, Development, and Health
- Maternal and Perinatal Health Interventions
- Prenatal Substance Exposure Effects
- Education Pedagogy and Practices
- Eicosanoids and Hypertension Pharmacology
- Infant Nutrition and Health
- Youth, Drugs, and Violence
- Fatty Acid Research and Health
- Maternal and fetal healthcare
- Business and Management Studies
- Pediatric health and respiratory diseases
Universidade de São Paulo
2018-2024
Seevic College
2021
Universidade Nove de Julho
2020
Instituto de Filosofía
2017
Aim No study has evaluated the betamethasone pharmacokinetics in twin pregnancies according to chorionicity. This aimed describe and compare pharmacokinetic parameters singleton dichorionic (DC) monochorionic third trimester of pregnancy. Methods Twenty‐six pregnant women received 2 intramuscular doses 6 mg sodium phosphate plus acetate due preterm labour. Serial blood samples were collected for 24 hours after first dose esters. Betamethasone plasma concentrations quantified using a...
Clinical experience shows an increased duration of labor in obese parturient women. It is unclear if this population should receive the same dose vaginal misoprostol for induction as non-obese We investigate influence obesity on pharmacokinetics and placental transfer metabolite acid Parturient women (n = 40) were enrolled received 25 µg/6 h vaginally allocated into two groups according to pre-pregnancy body mass index (BMI <30 kg/m
Abstract Clinical and experimental studies show an association between maternal periodontitis adverse outcomes during gestation. On the other hand, there were no evaluating impact of on offspring. Thus, our objective was to investigate repercussion development asthma in Pregnant rats submitted or not by ligature technique. Thirty days after birth, puppies sensitized challenged with ovalbumin (OVA) order induce asthmatic response. Our results showed that reduced cellular infiltrate parenchyma...
Betamethasone (BET) is a synthetic glucocorticoid recommended for pregnant women at imminent risk of preterm birth before 34 weeks to reduce neonatal complications. There are different techniques describe BET plasma quantification. However, none quantified the plasmatic concentration in dichorionic (DC) twin pregnancies using LC-MS. Our objectives were develop and validate method quantifying by LC-MS pharmacokinetic (PK) placental transfer studies DC pregnancies. Blood samples collected...
Aims: No study has evaluated the BET pharmacokinetics in twin pregnancies separated by chorionicity. The aim this is to describe and compare pharmacokinetic parameters singleton, dichorionic (DC) monochorionic (MC) third trimester of pregnancy. Methods: Twenty-six pregnant women received an intramuscular dose 6 mg sodium phosphate plus acetate. Serial blood samples were collected for 24 hours after first esters dose. plasma concentrations quantified using a validated HPLC analytical method....