A5039466424- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- CRISPR and Genetic Engineering
- RNA Interference and Gene Delivery
- Virus-based gene therapy research
- Immunotherapy and Immune Responses
- Hemoglobinopathies and Related Disorders
- Glycosylation and Glycoproteins Research
- Cell Adhesion Molecules Research
- Monoclonal and Polyclonal Antibodies Research
- Platelet Disorders and Treatments
- Hemophilia Treatment and Research
- Galectins and Cancer Biology
- Viral Infectious Diseases and Gene Expression in Insects
- Pancreatitis Pathology and Treatment
- Biochemical and Molecular Research
- Aquaculture Nutrition and Growth
- Parvovirus B19 Infection Studies
- T-cell and Retrovirus Studies
Hemophilia Center of Iran
2018-2021
Islamic Azad University, Science and Research Branch
2017-2020
Pasteur Institute of Iran
2017
The COVID-19 pandemic is now spreading throughout the world affecting agricultural activities including fish and shrimp culture sectors. Most of producing countries particularly in South-east Asia have been affected due to lockdown, quarantine roles regulations ordered by countries, which was assigned reduce control globe. current establishment restriction has significantly reduced domestic international transportations that can seriously affect supply chain world. Further, labor shortage,...
Abstract Blood-borne viruses including Hepatitis B and C, HIV, HTLV-1 parvovirus B19 are still a factor of concern, especially for hemophilia patients. Although the safety blood supply continues to improve worldwide, system in Afghanistan was damaged by many years conflict political instability. To date, there few studies focused on prevalence blood-borne This study is first investigate five patients four cities Kabul, Herat, Mazar-i-Sharif Jalal Abad. A total 80 male were screening presence...
Abstract Background Chronic hepatitis C (CHC) is one of the most important comorbidities in patients with hereditary bleeding disorders (HBD). The present study aimed at evaluating effectiveness direct-acting antiviral agent (DAA)-based interferon-free HCV regimens HBD. Patients and methods was performed on HBD CHC between 2015 2019. Sofosbuvir-based or without ribavirin were prescribed to treat infection. main endpoint determine sustained virologic response (SVR), assessed 12 weeks after...
Patients with thalassemia may also have cardiac abnormalities due to congenital problems, anemia, and increased burden of iron in their myocardium. This study was designed evaluate the effects direct acting antiviral (DAA) therapy on function hepatitis C virus (HCV)-infected patients thalassemia.HCV-infected were enrolled this prospective evaluation. Daily tablets 90 mg Ledipasvir (or 60 Daclatasvir) plus 400 Sofosbuvir (±ribavirin) prescribed for according Iran Hepatitis Network's...
Background: One of the challenges to treat hepatitis C virus (HCV) infection is activation B (HBV) that occurs during treatment HCV with direct-acting antivirals (DAAs) in some patients. The detection serum or liver HBV DNA absence HBsAg (HBV surface antigen) described as occult (OBI). Objectives: current study aimed at determining prevalence OBI Iranian DAA-naïve HCV-infected patients hemophilia. Methods: was conducted on 100 hemophilia receiving DAAs. sera obtained from these were tested...
High mobility group box 1 (HMGB1) is a highly conserved protein present in the nuclei and cytoplasm of cells which has an important role as mediator inflammation extracellular environment. HMGB1 was identified innate adjuvant that induces immune responses against soluble antigens vivo.Our goal generation recombinant HMGB1-GFP fusion insect for evaluation mouse model.In current study, we used baculovirus expression system based on with target gene (GFP), purified HMGB1- GFP protein. We then...
Molecular Study of Occult Hepatitis C Infection among Iranian Hemophilia Patients Treated with Direct-acting Antiviral Agents