A5100375143- Anesthesia and Neurotoxicity Research
- Neurogenesis and neuroplasticity mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Neonatal and fetal brain pathology
- Drug-Induced Adverse Reactions
- Myasthenia Gravis and Thymoma
- Intracerebral and Subarachnoid Hemorrhage Research
- Chemotherapy-related skin toxicity
- Functional Brain Connectivity Studies
- Nerve injury and regeneration
- Tryptophan and brain disorders
- Neural and Behavioral Psychology Studies
- Intensive Care Unit Cognitive Disorders
- Circular RNAs in diseases
- Neuroscience and Neuropharmacology Research
- Cancer, Stress, Anesthesia, and Immune Response
- Anesthesia and Sedative Agents
- Neurobiology of Language and Bilingualism
- Barrier Structure and Function Studies
- MicroRNA in disease regulation
- Eicosanoids and Hypertension Pharmacology
- Islamic Finance and Banking Studies
- Neurological Disease Mechanisms and Treatments
- Mental Health Research Topics
Capital Medical University
2023
Second Affiliated Hospital of Zhejiang University
2020-2023
Beijing Anding Hospital
2023
Lianyungang Oriental Hospital
2020
Xuzhou Medical College
2020
Taizhou University
2019
Background: Neuroinflammation is a frequent cause of brain damage after intracerebral hemorrhage (ICH). Gut microbiota are reported to regulate neuroinflammation. Berberine has been found have anti-inflammatory actions, including in the central nervous system. However, it not known whether berberine regulates neuroinflammation ICH, nor relationship between antineuroinflammatory actions and gut ICH understood. Methods: was induced male mice by collagenase injection. Immunofluorescent staining...
Stroke is one of the leading causes long-term disabilities worldwide. Although exposure to an enriched environment (EE) initiated in acute phase after stroke has neuroprotective effects and improves outcome, it remains unclear whether EE positive when started a delayed time frame. Here we show that notably ameliorates ischemia-induced impairments neurological functions spatial learning memory. In addition, significantly promotes survival neuronal fate choice hippocampal newborn cells,...
This study aimed to investigate the effects of stem cell-derived exosomes (SC-Exos) on learning, memory, and neuronal apoptosis in rats with cerebral ischemia-reperfusion injury determine whether SC-Exos exert their via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) pathway-mediated mitochondrial pathways apoptosis.Eighty were randomly allocated control, model, SC-Exos, PI3K inhibitor groups. A model focal was established using improved Longa method. Expression interleukin-1α...
Background and Purpose: Neurotoxicity of anesthetics has been widely observed by clinicians. It is reported that inflammation oxidative stress are involved in the pathological process. In present study, we aimed to assess therapeutic effects agomelatine against isoflurane-induced damage brain endothelial cells. Materials Methods: MTT assay was used detect cell viability order determine optimized concentration agomelatine. The bEnd.3 cells were treated with 2% isoflurane presence or absence...
Abstract Recent studies suggest that selective serotonin reuptake inhibitors (SSRIs) and exposure therapies have been used to reduced footshock-induced posttraumatic stress disorder (PTSD) symptoms. However, the therapeutic effect of combination SSRIs treatment with therapy remains a matter debate.This study aimed evaluate these through behavioral neuroimaging changes by positron emission tomography (PET) in model rats. We adopted Pavlovian fear conditioning paradigm establish rats, serial [...
Neural stem cell is a type of with self-renewal ability and multi-directional differentiation potential. Under certain conditions, neural cells can differentiate into neurons, oligodendrocytes, astrocytes, thereby participating in the occurrence nervous system. Considering that deep convolutional networks have better feature learning capabilities for image data than feedforward networks, this paper studies how to apply modeling based on imaging features, constructs networks. In paper,...