A5070420732- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy and Medication Impact
- COVID-19 Impact on Reproduction
- Genetic Neurodegenerative Diseases
- Tumors and Oncological Cases
- Congenital Diaphragmatic Hernia Studies
- Pregnancy and preeclampsia studies
- Tracheal and airway disorders
- Fetal and Pediatric Neurological Disorders
- Adolescent and Pediatric Healthcare
- Cardiomyopathy and Myosin Studies
- Muscle Physiology and Disorders
- Pregnancy-related medical research
- Maternal and Perinatal Health Interventions
Queen Elizabeth Hospital
2019-2024
Hong Kong Academy of Medicine
2020
ABSTRACT Objective To investigate the association of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) viral load and infection‐to‐delivery interval with maternal cord serum concentrations anti‐SARS‐CoV‐2 immunoglobulin G (IgG) antibodies transplacental transfer ratio in pregnant women active or recovered SARS‐CoV‐2 infection. Methods This was a prospective case series consecutive laboratory‐confirmed infection between 27 March 2020 24 January 2021. We collected information...
Autosomal recessive or compound heterozygous mutations in KLHL40 cause nemaline myopathy 8, which is one of the most severe forms myopathy. The c.1516A>C variant has recently been reported as a founder mutation southern Chinese.We report six cases 8 involves variant, from five unrelated families non-consanguineous Chinese. pre- and postnatal phenotypes these were reviewed with emphasis on prenatal clinical features. Genetic testing for was performed three patients homozygous mutations.Common...
Introduction: Postpartum haemorrhage is a major cause of maternal mortality and morbidity, commonly due to uterine atony.Prophylactic oxytocin use during Caesarean section recommended; patients with high risk postpartum may require additional uterotonics or procedures.Carbetocin long-acting analogue which has shown beneficial results, compared oxytocin.This study the requirement for procedures between at-risk women who underwent carbetocin infusion those infusion.Methods: This retrospective...
Abstract Introduction Our study compared the prospective risks of intrauterine fetal death (IUFD), neonatal (NND), perinatal (PND), and morbidities in monochorionic diamniotic (MCDA) dichorionic (DCDA) twin pregnancies. Methods This retrospective cohort included pregnancies who had antenatal care delivery a public hospital from 2011 to 2018. Exclusion criteria monoamnionicity, one/both miscarriage, twin‐twin transfusion syndrome, or lethal congenital abnormalities. All twins were managed...
To report the clinical maternal and fetal outcomes of pregnant women with coronavirus disease 2019 (COVID-19), along any associated pregnancy complications, in Hong Kong, China, to assess impact COVID-19 vaccination on these outcomes. This prospective registry-based observational study included who were recruited through convenient sampling had a laboratory-confirmed severe acute respiratory syndrome 2 infection cycle threshold (Ct) value result available admission eight local hospitals...
Detailed assessment of the larynx is not easy because its complex structures and associated technical difficulties. We performed sonography in multiple planes to assess laryngeal anatomy movements a fetus with atresia. The distended trachea ended abruptly an echogenic non-structured which showed shallow rapid "flutter-like" up down but adduction- abduction during swallowing. Shadowing from chin could be reduced by scanning through fluid oral cavity or between transverse processes vertebrae...
Bulleted Statements: What's already known about this topic? The incidence of discordant fetal sex was estimated to be 1 in 1500–2000. Comprehensive evaluation is required investigate the underlying cause. What does study add? Chimera one possible causes genotype–phenotype discordance. It could detected prenatally with combination noninvasive prenatal screening and ultrasound. Genetic counseling prospective parents on chimera can complex where early support information from experienced...