- Bipolar Disorder and Treatment
- Tryptophan and brain disorders
- Electroconvulsive Therapy Studies
- Stress Responses and Cortisol
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroendocrine regulation and behavior
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Electrolyte and hormonal disorders
- Alcoholism and Thiamine Deficiency
- Treatment of Major Depression
- Attachment and Relationship Dynamics
- Diet and metabolism studies
- Health, Environment, Cognitive Aging
- Transcranial Magnetic Stimulation Studies
- Folate and B Vitamins Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Thyroid Disorders and Treatments
- Fetal and Pediatric Neurological Disorders
- Potassium and Related Disorders
- Neuroscience and Music Perception
- Therapeutic Uses of Natural Elements
- Olfactory and Sensory Function Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Cardiac Health and Mental Health
Erciyes University
2004-2025
Bozok Universitesi
2016
It has been proposed that major depression is associated with a dysfunction of the gamma-aminobutyric acid (GABA) system. This study was planned to investigate whether there are any alterations in GABAergic activities depressive patients and, if are, electroconvulsive therapy (ECT) effect on these changes.Twenty-five depressed inpatients who responded course ECT and 23 healthy subjects were included study. Serum GABA levels measured 2 days before 10 minutes after first 3 last ECT, baclofen...
The aim of this study was to determine the effects anxiety levels and emotion dysregulation on each other their psychosocial functioning in remitted BD patients. Sixty-six patients with 38 healthy controls were included study. All assessed Hamilton Depression Rating Scale, Young Mania Bipolar Disorder Functioning Questionnaire, State-Trait Anxiety Inventory (STAI) Difficulties Emotion Regulation Scale (DERS). Healthy only STAI DERS. DERS scores significantly higher patient group than control...
The efficacy of a centrally active cholinesterase inhibitor, rivastigmine tartrate (ENA 713), in patients with advanced moderate Alzheimer's disease (AD) was evaluated 12-month placebo-controlled study. We aimed to investigate whether there any evidence for the benefits severe disease. These were compared matched controls. In this study, 24 AD received 12 months. Another 20 placebo. Mean daily doses higher-dose group at 3, 6, 9, and months 6.1 +/- 1.0, 8.3 1.2, 8.9 1.3, 10.7 1.6 mg/day,...
Many studies have reported that psychiatric disorders may be associated with oxytocin receptor (OXTR) gene polymorphisms. The aim of this study was to investigate whether there is a relationship between OXTR polymorphisms and bipolar disorder (BPD). included 100 patients diagnosed BPD type 1 (BPD I) 96 healthy controls. Single nucleotide (SNPs) the gene, including rs53576, rs2254298 rs2268494, were examined via polymerase chain reaction in blood samples taken from participants. Based on...
Aim: To evaluate the presence of relationship between depression and proinflammatory cytokine levels in hemodialysis (HD) patients. Methods: The study included 40 HD patients 20 healthy controls. All participants were evaluated for using structured clinical interview based on criteria defined by Diagnostic Statistical Manual Mental Disorders (Fourth Edition, Text Revision) Axis I disorders. severity depressive symptoms was assessed Beck Depression Inventory, Hamilton Rating Scale, Anxiety...
Mega cisterna magna is a part of "Dandy-Walker Complex" and it characterized by the enlargement magna, morphologically intact vermis cerebellar hemispheres. We report case manic attack in 23-year-old man with mega magna. The patient was treated quetiapine 1,000 mg/day sodium valproate 1,500 symptoms were ameliorated within 2.5 months. In this case, may be found together coincidentally or any dysfunction due to cause contribute appearance affective symptoms. To our knowledge, first reporting...
Abstract Objective This study investigated thyroid volume, hormone levels and antibodies in long‐term lithium‐treated lithium‐naïve bipolar patients, some of whom underwent prospective follow‐up evaluations. Methods Fourteen 13 patients diagnosed with disorder 12 healthy controls were included. Seven followed‐up during their lithium receiving period (range 6–9 months). Thyroid volume serum hormones measured once the controls, twice i.e. before after treatment. Results Mean volumes...
Background: To investigate the relationship between depression, nutritional status, and inflammatory markers in patients on peritoneal dialysis (PD). Patients Methods: This prospective study included 40 PD 20 healthy people. The severity of depressive symptoms was assessed using Beck Depression Inventory, Hamilton Rating Scale, Anxiety Scale. received antidepressant drug for 8 weeks. Blood samples were taken before after treatment high-sensitive C-reactive protein (hs-CRP), interleukin...
Mental fatigue, cognitive disorders, and sleep disturbances seen in chronic fatigue syndrome (CFS) may be attributed to cholinergic deficit. A functional deficiency of neurotransmission cause the hypothalamic-pituitary-adrenal axis hypoactivity CFS. Therefore, we investigated alterations stress hormones such as cortisol dehydroepiandrosterone sulfate (DHEAS) CFS patients before after 4-week administration galantamine hydrobromide, a selective acetylcholinesterase inhibitor, aimed investigate...
We investigated the acute and lasting effects of electroconvulsive therapy (ECT) on thyroid-stimulating hormone (TSH) response to thyrotropin-releasing (TRH) in patients with depression. The TRH stimulation test was conducted (1) under basal conditions, after a first ECT, at end therapeutic course 7 ECTs 20 inpatients depression; (2) before initiation antidepressant 16 other depression who responded drug treatment; (3) healthy control subjects. Baseline TSH levels were lower depression,...
Objective: The neuropeptide arginine vasopressin (AVP) has effects on behavior and stress regulations which are impaired in bipolar disorder (BD). Only a very limited number of studies have investigated AVP levels contrast to depressive disorders. study aimed investigate serum during the manic, depressive, or remission periods after treatment response patients with I (BD-I) healthy controls. Methods: consisted 67 BD-I 24 were BD-I. Serum assayed three groups controls at onset. Then, second...