A5064525590- E-Learning and Knowledge Management
- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Systemic Sclerosis and Related Diseases
- Innovative Teaching Methods
- Rheumatoid Arthritis Research and Therapies
- Atherosclerosis and Cardiovascular Diseases
- Online and Blended Learning
- Pancreatic function and diabetes
- Aortic aneurysm repair treatments
- Innovative Educational Technologies
- Educational Technology in Learning
- Diabetes and associated disorders
- Alcohol Consumption and Health Effects
- Adipokines, Inflammation, and Metabolic Diseases
- Experimental Learning in Engineering
- Hip and Femur Fractures
- Immune cells in cancer
- Pleural and Pulmonary Diseases
- Pharmacology and Obesity Treatment
- Spondyloarthritis Studies and Treatments
- Endoplasmic Reticulum Stress and Disease
- Metabolism, Diabetes, and Cancer
- Technology in Education and Healthcare
- Hematological disorders and diagnostics
INCLIVA Health Research Institute
2020-2024
Hospital Universitario Doctor Peset
2024
Universidad Europea
2021
Historically, traditional laboratory experiments have been given a central and distinctive role in science education. However, virtual laboratories received considerable attention over the past several years different areas of knowledge. The main aim this study is to analyse impact use both Basic Science Subjects (BSS) Health Sciences university degrees. For reason, we described analysed variables such as level satisfaction, increase perceived motivation academic performance. Throughout...
Nonalcoholic fatty liver disease (NAFLD) is reaching pandemic proportions due to overnutrition. The understanding of advanced stages that recapitulate the human pathology great importance get a better mechanistic insight. We hypothesized feeding WT (C57BL) mice with diet containing high content fat (21%), sugar (41.5%) and 1.25% cholesterol (called from now on fat, sucrose diet, HFSCD) will reproduce characteristics severity. Analysis 16 weeks HFSCD-fed demonstrated increased weight...
Abdominal aortic aneurysm (AAA), is a complex disorder characterized by vascular vessel wall remodeling. LIGHT (TNFSF14) proinflammatory cytokine associated with disease. In the present study, impact of genetic inactivation Light was investigated in dissecting AAA induced angiotensin II (AngII) Apolipoprotein E-deficient (Apoe-/-) mice. Studies human (ah) smooth muscle cells (VSMC) to study potential translation pathology were also performed. AngII-treated Apoe-/-Light-/- mice displayed...
Type 2 diabetes mellitus (T2DM) increases morbimortality in humans via enhanced susceptibility to cardiovascular disease (CVD). Sodium-glucose co-transporter inhibitors (SGLT2i) are drugs designed for T2DM treatment diminish hyperglycaemia by reducing up 90% of renal tube glucose reabsorption. Clinical studies also suggest a beneficial action SGLT2i heart failure and CVD independent its hypoglycaemiant effect. In the present study, we explored effect dapagliflozin (DAPA) metabolism...
<h3>Background:</h3> Systemic autoimmune diseases, including systemic sclerosis (SSc), are associated with early atherosclerosis. Hematological indices, such as: Neutrophil-Lymphocyte Ratios (NLR), Platelet-Neutrophil (PNR) and Platelet-Lymphocyte (PLR), related to inflammation In SSc, NLR could predict disease progression mortality. <h3>Objectives:</h3> To evaluate the potential value of baseline NLR, PNR PLR determination as predictors subclinical vascular damage (atherosclerosis), major...
<h3>Background:</h3> Systemic sclerosis (SSc) is a disease with high morbidity and mortality. As other autoimmune systemic diseases, it associated early atherosclerosis increased cardiovascular risk. Nailfold capillaroscopy widely use method for the diagnosis monitoring of SSc. <h3>Objectives:</h3> To describe frequency subclinical vascular damage, major adverse events (MACEs) mortality in cohort patients analyse association predictive value nailfold at time diagnosis, MACEs deaths....
Previous research suggests a potential involvement of the cytokine LIGHT (TNFSF14) in atherosclerosis. In this study, genetic inactivation Light Apolipoprotein E deficient mice (male and female C57BL) augmented plaque size vulnerability while decreasing Treg cells. Human mouse transcriptomic results demonstrated deranged immune pathways human atheromas with low expression levels Light-deficient murine atheromas. agreement this, vitro LIGHT-treatment lymphocytes, induced an elevation cell...
<h3>Background:</h3> Hematological indices, such as neutrophil-to-lymphocyte (NLR), platelets-to-lymphocyte (PLR), lymphocyte-to-monocyte (MLR), lymphocyte-to-C-reactive protein (LCR) and platelet-to-neutrophil (PNR) ratios; have been proposed potential prognostic biomarkers for cardiovascular diseases. Rheumatoid arthritis (RA) is an inflammatory chronic joint disease known to increase risk early atherosclerosis. <h3>Objectives:</h3> To evaluate the association of hematological indices:...