Abstract In this study, immobilization of laccase (L) enzyme on magnetite (Fe 3 O 4 ) nanoparticles was achieved, so that the immobilized could be used repeatedly. For purpose, Fe were coated and functionalized with chitosan (CS) from Trametes versicolor onto chitosan‐coated magnetic ‐CS) by adsorption or covalent binding after activating hydroxyl groups carbodiimide (EDAC) cyanuric chloride (CC). nanoparticles, thickness CS layer estimated as 1.0–4.8 nm TEM, isoelectric point detected 6.86...

Abstract Removal of dyes from the industrial discharge water is an important issue for safety environment. In this study, magnetic (magnetite, Fe 3 O 4 ) nanoparticles were coated with chitosan (CS) and efficiency these (Fe ‐CS) adsorption a reactive textile dye (Reactive Yellow 145, RY145) was examined first time in literature. TEM, XRD, EPR results revealed that thickness coat about 2–5 nm, no phase change spinel structure particles existed after coating, had paramagnetic property,...

Polyurethanes are known as a class of polymers with very high ‘hemocompatible‘ properties. In this study polyurethanes were prepared in various compositions and medical purity without using any solvent, catalyst or additives. For the synthesis polyurethanes, toluene diisocynate, diphenylmethane diisocynate hexamethylene used diisocyanate compounds polypropylene-ethylene glycol polypropylene polyol compounds. The surfaces modified plasma glow-discharge by gas atmospheres applying different...

Polymethylmethacrylate (PMMA) films were modified by RF oxygen plasma with various powers applied for different periods, and the effects of these parameters on surface properties such as hydrophilicity, free energy (SFE), chemistry, topography investigated water contact angle, goniometer, X‐ray photoelectron spectroscopy (XPS), atomic force microscopy, types created radicals their decay detected electron spin resonance (ESR). SFE angle results varied depending parameters. Oxygen treatment...

Infections caused by bacteria adhering to implant surfaces are one of the main reasons for failure implants. In this study, polyurethane (PU), which is most commonly used polymer in production medical devices, was synthesized and films were modified chitosan (CH) grafting heparin (Hep) immobilization order enhance anti-adhesiveness antibacterial properties. Functional groups present on surface, topographical shapes, free energies determined. Pristine polyurethane, chitosan-grafted (PU–CH),...

A key challenge in skeletal muscle tissue engineering is the choice of a proper scaffolding material as it should demonstrate elastic behavior to withstand and support dynamic loading microenvironment while being biodegradable biocompatible. In this study, we tested applicability novel polyurethane (PU) elastomer chain extended with fibrinogen (Fib) fulfill these requirements. Biodegradable polyurethane-fibrinogen (PU-Fib) elastomers were synthesized by step-wise condensation polymerization....

Abstract In this study, antibacterial properties were induced in polyurethane (PU) films by the incorporation of Ag + ‐loaded zeolites as fillers. The mechanical and thermal prepared composites also investigated. For purpose, two different types zeolite microparticles, high‐silica beta crystals low‐silica A crystals, synthesized. was added ion exchange, these particles incorporated into PU prepolymer, which from its main components toluene diisocyanate polypropylene ethylene glycol (medical...

Abstract Thrombus formation and blood coagulation is a major problem associated with contacting products such as catheters, vascular grafts, arteries, artificial hearts heart valves. An intense research being conducted towards the synthesis of new hemocompatible materials modifications surfaces biological molecules. In this study, polyurethane (PU) films were synthesized in medical purity from diisocyanate polyol without using any other ingredients their modified by covalent immobilization...

Polyurethane surfaces were modified by covalent immobilization of different molecular weight heparins (fractionated Mw ~3000 Da, and unfractionated ~17,000—19,000 Da) examined ESCA, AFM, contact angle goniometer. The effect these surface-immobilized on blood protein adsorption platelet adhesion, after incubating the samples with platelet-poor platelet-rich plasma. Protein kinetics was studied electrophoresis platelets adhered SEM incubation. two heparin types clearly showed behavior respect...

ABSTRACT In this study, novel poly(ε‐caprolactone) (PCL) composite scaffolds were prepared for bone tissue engineering applications, where gentamicin‐loaded β‐tricalcium phosphate (β‐TCP)/gelatin microspheres added to PCL. The effects of the amount β‐TCP/gelatin PCL scaffold on various properties, such as gentamicin release rate, biodegradability, morphology, mechanical strength, and pore size distribution, investigated. A higher filler caused a reduction in properties an increase led faster...

Abstract Incorporation of zeolite into polyurethane (PU) membranes was investigated by using as‐synthesized and calcined beta particles at two different loading contents (0.1 1 wt %). The chemical interaction between the crystals PU observed ATR‐FTIR spectroscopy. SEM results suggested that were more homogeneously dispersed in composite than crystals. DMA demonstrated all had higher storage modulus rubbery state stability towards thermal mechanical degradation with respect to control groups....

Ibuprofen is a non-steroidal anti-inflammatory drug for the treatment of Rheumatoid Arthritis and osteoarthritis. In this study, we prepared topical gel network enhancement ibuprofen penetration, maintenance controlled release increased patient compliance. Nanoparticles containing were by means emulsion formation/solvent diffusion method using synthesized copolymer. then conjugated with aminoethylmethacrylate, resulting in ibuprofen-loaded nanoparticles PLGA-b-PEG-MA structure....

Abstract In this work, novel antibacterial composites were prepared by using poly(ε‐caprolactone) (PCL) as the main matrix material, and gentamicin‐loaded microspheres composed of β‐tricalcium phosphate (β‐TCP) gelatin. The purpose is to use biodegradable material a support for bone tissue. This composite system expected enhance regeneration presence β‐TCP prevent possible infection that might occur around defected region release gentamicin. effects ratio β‐TCP/gelatin on morphological,...

ABSTRACT Polyurethanes (PUs) are the most widely used polymers because of their biocompatibility, tunable mechanical properties, and chemical versatility. In this study, a two‐step condensation polymerization polycaprolactone diol hexamethylene diisocyanate was carried out, glutamic acid ester derivative, (2 S )‐bis(2‐hydroxypropyl) 2‐aminopentane dioate (HPAP), as new chain extender to accelerate biodegradation properties PU. HPAP synthesized by Fischer esterification l ‐glutamic acid. The...

Abstract In this study, novel composite bone fillers with microspherical shape, biodegradable property, and antibacterial effect were designed prepared. Various different β‐tricalcium phosphate (β‐TCP)/gelatin (G)/glutaraldeyde (GA) compositions loaded a model antibiotic, gentamicin. The of composition preparation conditions on the release gentamicin was investigated in vitro conditions. Complete observed 12 h for pure β‐TCP powder, period extended up to 96 as gelatin content increased...