A5053799391- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
- Neuroscience and Music Perception
- Noise Effects and Management
- Neuroscience and Neural Engineering
- Neuroendocrine regulation and behavior
- Receptor Mechanisms and Signaling
- Memory and Neural Mechanisms
- Neurobiology and Insect Physiology Research
- Phagocytosis and Immune Regulation
- Monoclonal and Polyclonal Antibodies Research
Allen Institute
2020
Allen Institute for Brain Science
2020
University of Oregon
2016-2018
Cortical circuits can flexibly change with experience and learning, but the effects on specific cell types, including distinct inhibitory are not well understood. Here we investigated how excitatory VIP cells in layer 2/3 of mouse visual cortex were impacted by context a behavioral task. Mice learned detection task set eight natural scene images. Subsequently, during 2-photon imaging experiments, mice performed these familiar images three sets novel Strikingly, temporal dynamics activity...
The neuronal pathways that link sounds to rewarded actions remain elusive. For instance, it is unclear whether neurons in the posterior tail of dorsal striatum (which receive direct input from auditory system) mediate action selection, as other striatal circuits do. Here, we examine role decisions mice. We find that, contrast anterior striatum, activation does not elicit systematic movement. However, during sound presentation an discrimination task biases animals' choices, and transient...
Multiple parallel neural pathways link sound-related signals to behavioral responses. For instance, the striatum, a brain structure involved in action selection and reward-related learning, receives neuronal projections from both auditory thalamus cortex. It is not clear whether sound information that reaches striatum through these two redundant or complementary. We used an optogenetic approach awake mice of sexes identify thalamostriatal corticostriatal neurons during extracellular...
Abstract The neuronal pathways that link sounds to rewarded actions remain elusive. It is unclear whether neurons in the posterior tail of dorsal striatum (which receive direct input from auditory system) mediate action selection, as other striatal circuits do. Here, we examined role decisions mice. We found that, contrast anterior striatum, activation did not elicit systematic movement. However, during sound presentation an discrimination task biased animals’ choices, and transient...