A5101592721- Spine and Intervertebral Disc Pathology
- Gastrointestinal disorders and treatments
- Genetic factors in colorectal cancer
- Soft tissue tumor case studies
- Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- Mesenchymal stem cell research
- Sinusitis and nasal conditions
- Liver Disease and Transplantation
- Sarcoma Diagnosis and Treatment
- Ear Surgery and Otitis Media
- Medical Imaging and Analysis
- Tumors and Oncological Cases
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Tracheal and airway disorders
- Musculoskeletal pain and rehabilitation
- Oral and Maxillofacial Pathology
- Osteoarthritis Treatment and Mechanisms
- Bone Tumor Diagnosis and Treatments
- Phytoestrogen effects and research
- Abdominal Trauma and Injuries
- Heterotopic Ossification and Related Conditions
- Colorectal and Anal Carcinomas
General Hospital of Attica
2022
Psychiatric Medical Center
2022
University of Gothenburg
2014-2021
Sahlgrenska University Hospital
2012-2021
University General Hospital Attikon
2019
G. Papanikolaou General Hospital
2010-2013
Aristotle University of Thessaloniki
2013
Institute of Clinical Research
2013
Lister Hospital
2007
Pirogov Russian National Research Medical University
1994
Low back pain is common and degenerated discs (DDs) are believed to be a major cause. In non-degenerated intervertebral (IVDs) presence of stem/progenitor cells was recently reported in different mammals (rabbit, rat, pig). Understanding processes disc degeneration regenerative mechanisms within DDs important. The aim the study examine local human if these cell populations could respond paracrine stimulation vitro. Tissue biopsies from IVD region (L3-S1) were collected 15 patients, age 34-69...
Low back pain is a major health issue and one main cause to this condition believed be intervertebral disc (IVD) degeneration. Stem cell therapy for degenerated discs using mesenchymal stromal cells (MSCs) has been suggested. The aim of the study was investigate presence distribution pattern autologous MSCs transplanted into IVDs in patients explanted posttransplantation. IVD tissues from four (41, 45, 47, 47 years age) participating clinical feasibility on MSC transplantation degenerative...
For evaluation of cell therapy strategies using human mesenchymal stem cells (hMSCs), it is important to be able trace transplanted and their distribution in tissues, for example, cartilage, over time. The aim the study was determine effects on viability, traceability, chondrogenic differentiation hMSCs after iron labeling with sucrose. were collected (seven donors, 13-57 years) from patients undergoing spinal surgery. Two subsets experiments performed. (1) Iron hMSCs: 1 mg/mL Venofer(®)...
Occurrence of malignancy in a thyroglossal duct cyst (TDC) children and adolescents is very rare, preoperative diagnosis challenge, appropriate management still debated. We report 19-year-old male patient referred for midline neck mass diagnosed as an atypical TDC after initial subsequent investigations. Ultrasound-guided fine-needle aspiration (FNA) the was diagnostic papillary thyroid carcinoma. Sistrunk procedure total thyroidectomy were performed. Histologic analysis confirmed presence...
For evaluation of cell therapy applications, it is interest to be able trace and observe cellular distribution the transplanted cells. The aim with study was examine viability, traceability, multilineage capability iron sucrose-labeled mesenchymal stem cells (MSCs) after transplantation into lapine intervertebral discs (IVDs). MSCs were collected from three human donors, age 31-50 years, IVDs 12 rabbits, 3 months. isolated bone marrow cultured using standard protocols. Iron sucrose labeling...
<b><i>Background:</i></b> Moderate exercise regimens have shown minor positive effects on matrix turnover in articular cartilage (AC), while at cellular level, e.g. proliferation, are scarcely described. <b><i>Aim:</i></b> The aim of this study was to investigate the moderate cell proliferation and recruitment cells possibly active regeneration different regions rat knee joint. <b><i>Methods:</i></b> Eighteen rats were...
<h3>Purpose</h3> Degeneration of the intervertebral disc is considered to be central in pain pathogenesis patients suffering from chronic low back (LBP). In recent years, injection mesenchymal stromal cells (MSCs) into arrest or reverse degenerative process has been proposed as an alternative therapy. The aim present study was investigate feasibility using iron-labeled MSCs for intradiscal with long-standing LBP. <h3>Methods</h3> Ten (7 men, 3 women, mean age 40 range 26–53) LBP and...
Peutz-Jeghers syndrome is a rare hereditary autosomal dominant disease caused by mutation of the tumor suppressor gene serine/threonine kinase 11 located in chromosome 19p13.3.It characterized presence extensive mucocutaneous pigmentation, especially lips and occurrence hamartomatous polyps throughout gastrointestinal tract.Gastrointestinal hamartomas occur predominantly small intestine can become symptomatic leading usually to intestinal obstruction abdominal pain.We present case recurrent...
Familial adenomatous polyposis (FAP) is a rare syndrome characterized by the presence of hundreds to thousands colorectal adenomas and responsible for less than 1% all cancers.The also extra-colorectal features including amongst others upper gastrointestinal tract polyps desmoid tumors.The inherited an autosomal dominant gene, coli (APC) gene.We present physical history, clinical presentation, diagnosis treatment patient with novel germline APC mutation, W421X which resulted in FAP...