A5102116063- Monoclonal and Polyclonal Antibodies Research
- Rheumatoid Arthritis Research and Therapies
- Toxin Mechanisms and Immunotoxins
- RNA modifications and cancer
- Porphyrin and Phthalocyanine Chemistry
- Swearing, Euphemism, Multilingualism
- Carbohydrate Chemistry and Synthesis
- Big Data Technologies and Applications
- CRISPR and Genetic Engineering
- Abdominal Trauma and Injuries
- Ion Transport and Channel Regulation
- EFL/ESL Teaching and Learning
- Immunotherapy and Immune Responses
- RNA and protein synthesis mechanisms
- Advanced Biosensing Techniques and Applications
- RNA Research and Splicing
- Virology and Viral Diseases
- Data-Driven Disease Surveillance
- T-cell and B-cell Immunology
- interferon and immune responses
- Corneal surgery and disorders
- vaccines and immunoinformatics approaches
- Mathematics and Applications
- Ion Channels and Receptors
- Discourse Analysis in Language Studies
The University of Texas at Austin
2024-2025
Tiangong University
2022
New York Structural Biology Center
2020
Northeast Agricultural University
2012-2014
Shanghai Liangyou (China)
2010
Jinan Central Hospital
2010
A previous study found that a domesticated bacterial group II intron-like reverse transcriptase (G2L4 RT) functions in double-strand break repair (DSBR) via microhomology-mediated end joining (MMEJ) and mobile intron-encoded RT has basal DSBR activity uses conserved structural features of non-LTR-retroelement RTs. Here, we determined G2L4 apoenzyme snap-back DNA synthesis structures revealing novel adaptations optimized its cellular function DSBR. These included unique RT3a structure...
A recent study found that a bacterial chromosomally encoded group II intron-like reverse transcriptase (G2L4 RT) functions in double-strand break repair (DSBR) via microhomology-mediated end joining (MMEJ) and this function is dependent upon conserved structural features of non-LTR-retroelement RTs, family enzymes includes RTs as well human LINE-1 other eukaryotic non-LTR-retrotransposon RTs. Here, we determined apoenzyme co-crystal structures G2L4 RT revealed the structual basis its MMEJ...
Objective To express the anti-IL-1βscfv and soluble TNF receptor 1 (sTNFR1),and analyze their bio-activities.Methods sTNFR1 was obtained by RT-PCR from total RNA of HeLa cells,and fused with IL-1βscfv hinge fragment IgG molecule.The fusion gene IL-1scfv:TNFR1 cloned into expression vector pET27b(+).The protein expressed purified inclusion bodies.Results The ELISA analysis showed that could bind hIL-1β hTNF-α respectively in a dose-dependent manner,indicating scfv sTNFR can form correct...
Under the rapid development of economy and society, process financial sector is also accelerating now. Nowadays, a variety data information emerging, how to fully combine these big with field key topic general concern in field, combination two can make effective use various data, so as promote healthy sustainable entire field. Therefore, this paper focuses on specific application computer finance, which has practical significance.